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AI Podcasts

December 18, 2025

How to build an AI native company (even if your company is 50 years old) – Dan Shipper, Every

AI Engineer

AI
Key Takeaways:
  1. The 100% AI adoption threshold is a step-function change, not incremental. Companies that commit fully will outpace those with partial integration.
  2. Builders should prioritize "compounding engineering" by codifying knowledge into reusable prompts. This builds an organizational memory that accelerates future development exponentially.
  3. Re-evaluate team structures and roles. Single engineers can own complex products, and even technical managers can contribute code, shifting how organizations operate.
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December 18, 2025

AI Consulting in Practice – NLW, Super ai

AI Engineer

AI
Key Takeaways:
  1. The Agent Economy is Here: Enterprises are moving past pilots with AI agents. Builders should focus on orchestration layers and human-agent interaction design.
  2. ROI Measurement is the Next Frontier: Investors should look for solutions that help organizations accurately track and attribute AI value beyond traditional metrics.
  3. Strategic AI, Not Spot Solutions: The biggest wins come from systematic, cross-organizational AI strategies that target new capabilities and revenue growth, not just incremental time savings.
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December 18, 2025

The EU and the not-so-simple macroeconomics of AI – Luis Garicano

Epoch AI

AI
Key Takeaways:
  1. Strategic Implication: The global AI race is a zero-sum game for foundational models. Europe's best strategy is a "smart second mover" approach, focusing on the implementation layer by ensuring interoperability and data portability.
  2. Builder/Investor Note: Invest in AI that achieves true autonomy and enhances expert productivity. Be wary of markets stifled by over-regulation, which can impede AI adoption and growth.
  3. The "So What?": Europe faces a critical juncture. Without embracing AI-driven growth, its demographic and debt problems will worsen, leading to higher interest rates without the corresponding economic expansion.
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December 18, 2025

Two Futures | Runtime 2025

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next decade will be defined by who builds the core infrastructure for intelligence. This is where the most significant value and influence will accrue.
  2. Builder/Investor Note: Direct capital and talent towards foundational AI components—chips, models, and interoperable systems. Avoid the temptation to only build at the application layer.
  3. The So What?: The window for shaping the future of intelligence is now. Engage in the deepest, most complex challenges to secure a footprint in this new era.
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December 18, 2025

Two Futures | Runtime 2025

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next decade's value will accrue to those building foundational AI infrastructure and the "invisible layers" that connect intelligent systems.
  2. Builder/Investor Note: Focus capital and talent on core AI models, specialized domain intelligence, and the underlying computational fabric. Superficial applications risk rapid commoditization.
  3. The So What?: This is the defining period for the architecture of global intelligence. Participation now determines future influence and relevance.
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December 17, 2025

Rethinking Pre-Training for Agentic AI [Aakanksha Chowdhery] - 759

The TWIML AI Podcast with Sam Charrington

AI
Key Takeaways:
  1. Strategic Implication: The next frontier in AI is agentic, and progress hinges on fundamental pre-training innovation, not just post-training optimizations.
  2. Builder/Investor Note: Focus on teams with deep experience in scaling and debugging large models, as this is a high-capital, high-risk endeavor. Builders should prioritize developing new benchmarks for agentic capabilities.
  3. The "So What?": The industry needs to move beyond next-token prediction and static benchmarks to unlock truly capable, self-correcting AI agents in the next 6-12 months.
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December 17, 2025

Rethinking Pre-Training for Agentic AI [Aakanksha Chowdhery] - 759

The TWIML AI Podcast with Sam Charrington

AI
Key Takeaways:
  1. Pre-Training is the New Frontier: The next leap in AI capabilities, particularly for agentic systems, will come from fundamental advancements in pre-training, not just post-training tweaks.
  2. Builders & Investors: Focus on teams rethinking loss objectives, curating high-quality reasoning data, and developing dynamic benchmarks for agentic capabilities. Be wary of "agentic" claims that lack foundational pre-training innovation.
  3. The "So What?": Over the next 6-12 months, expect a push for new benchmarks and data strategies that explicitly train models for multi-step planning, long-form reasoning, and error recovery, moving beyond simple next-token prediction.
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December 17, 2025

Code World Model: Building World Models for Computation – Jacob Kahn, FAIR Meta

AI Engineer

AI
Key Takeaways:
  1. Shift in AI Development: The focus moves from syntax-aware code generation to execution-aware reasoning, enabling more robust and intelligent code agents.
  2. Builder/Investor Note: Prioritize tools and platforms that support explicit execution modeling and highly asynchronous, high-throughput RL training for agentic systems.
  3. The "So What?": AI that can simulate complex systems internally will drastically reduce development and testing costs, accelerating innovation in software and distributed systems over the next 6-12 months.
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December 17, 2025

AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs

AI Engineer

AI
Key Takeaways:
  1. Strategic Shift: AI-driven kernel generation is not replacing human genius but augmenting it, allowing experts to focus on novel breakthroughs while AI automates the application of known optimizations across a complex hardware landscape.
  2. Builder/Investor Note: Focus on robust validation and hardware-in-the-loop systems. Claims of "AI inventing new algorithms" in this domain are premature. The real value is in automating the "bag of tricks" for heterogeneous compute.
  3. The "So What?": This technology is critical for scaling agentic AI workloads. Expect significant investment in tools that abstract hardware complexity and enable efficient, automated optimization, driving down the cost of AI inference in the next 6-12 months.
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Crypto Podcasts

October 20, 2025

Welcome to Forward Guidance

Forward Guidance

Crypto
Key Takeaways:
  1. Stop Reacting, Start Anticipating: The market’s direction is a better economic predictor than official data. Focus on forward guidance, not rearview-mirror analysis.
  2. Bitcoin Is a Macro Asset: The primary thesis for assets like Bitcoin stems from the structural debasement of fiat currencies. Analyze it through the lens of global liquidity and monetary policy.
  3. Trust the Market, Not the Fed: The bond market can and will reject central bank policy. When market signals contradict official narratives, pay attention—the market is often right.
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October 20, 2025

How Futarchy Ends the Rug Pull Era

Bankless

Crypto
Key Takeaways:
  1. From Voting to Value: Futarchy transforms governance from a popularity contest into a pure value-maximization engine, where the only thing that matters is whether a decision increases the token's price.
  2. Investor Protection on-Chain: By locking funds in a market-governed treasury, Futarchy offers automated, code-enforced investor protections that mimic—and may even surpass—traditional shareholder rights.
  3. The End of the Rug Pull Era: Platforms like MetaDAO create a new asset class of "ownership coins" where the incentive to rug is eliminated, signaling a potential turning point for the quality and reliability of crypto investments.
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October 17, 2025

Gold Hits All-Time Highs, Stablecoin Adoption, and Historic Liquidations | Roundup

Bell Curve

Crypto
Key Takeaways:
  1. **The Four-Year Cycle Is Dead.** The absence of a parabolic, post-halving rally confirms a new paradigm. Investors should expect more sustained, multi-year growth fueled by institutional adoption and macro trends, pointing to a strong 2026.
  2. **Stablecoins Are Capital Formation Engines.** The primary use case isn't peer-to-peer payments; it's a new financial primitive for funding real-world assets. This is crypto’s killer app for institutions.
  3. **DeFi's Transparency Wins.** The recent liquidations proved that while CeFi remains a house of cards with opaque risks and preferential treatment for insiders, DeFi’s transparent, on-chain systems offer superior resilience.
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October 17, 2025

Inside the Minds Shaping the Next Internet

The DCo Podcast

Crypto
Key Takeaways:
  1. **Invisible Blockchain is the Endgame.** The biggest barrier to mass adoption is user experience. The ultimate winners will make crypto so seamless that users don't even realize they're using it.
  2. **Revenue Beats Hype.** The industry is maturing from extractive schemes to sustainable businesses. Valuations must follow suit, focusing on ecosystem health, attention, and earned revenue—not just mints.
  3. **Coordination Creates Wealth.** Crypto's core innovation is "human coordination on steroids," a force powerful enough to potentially trigger the largest single wealth creation event in the internet's history.
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October 17, 2025

Crypto Has Topped.

Taiki Maeda

Crypto
Key Takeaways:
  1. Altcoins Are Cooked. A decimated retail buyer base combined with relentless selling pressure from insider token unlocks creates a structurally bearish environment for the entire altcoin complex.
  2. Farm, Don't Buy. Stop being exit liquidity. The winning strategy is to farm airdrops to acquire tokens for free and become the one who sells at launch.
  3. Capital Preservation is King. The "one more 2x" mentality is a trap. Protect your gains by holding significant stablecoin reserves and acting quickly to de-risk. Take care of the downside, and the upside will take care of itself.
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October 17, 2025

DAS Takeaways, Crypto’s Largest Liquidation Ever & Have We Peaked? | Weekly Roundup

Empire

Crypto
Key Takeaways:
  1. **The Great Bifurcation Is Here.** Institutional capital is flowing into Bitcoin and Ethereum, but the flash crash proved the altcoin market is a liquidity desert. Do not mistake ETF inflows for broad market support.
  2. **DeFi Won the Battle, CeFi Won the War (For Now).** Protocols like Aave performed perfectly, but the system's reliance on centralized exchange oracles was the critical point of failure. The future is hybrid, but the current integration is dangerously fragile.
  3. **Cash Flow Is King.** The era of vaporware is ending. From DATs to new tokens, the market will no longer tolerate projects without a clear path to revenue. The music has stopped for assets without a viable business model.
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