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AI Podcasts

November 17, 2025

Emmett Shear on Building AI That Actually Cares: Beyond Control and Steering

a16z

AI
Key Takeaways:
  1. Stop Trying to “Steer” AGI. The control paradigm is a dead end. The goal isn’t a more obedient tool; it’s a trustworthy teammate. We must shift from engineering control to cultivating care.
  2. Alignment is a Process, Not a Product. True alignment isn't a fixed set of rules. It’s a dynamic process of moral learning, akin to raising a child. AIs that only follow rules are brittle and dangerous.
  3. Build for Cooperation, Not Command. The technical path forward involves training AIs in rich, multi-agent environments where they must learn cooperation and theory of mind—the foundational skills for becoming a good member of a group.
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November 16, 2025

Rawson Haverty presents "US & China AI: Lessons from Across the Pacific" | dAGI Summit 2025

Delphi Digital

AI
Key Takeaways:
  1. US Leads in Capital-Intensive Frontier AI; China Excels at Industrial Diffusion. The US leverages deep capital markets for its massive compute buildout and AGI research, while China uses state direction to embed AI into its vast industrial base via open-source models and hardware.
  2. Market Structure Dictates AI Strategy. The US "efficient oligopoly" model prioritizes global dominance and profit reinvestment by a few players. China's "subjugated swarm" model creates intense domestic competition, driving down prices and accelerating adoption at the cost of profitability.
  3. Geopolitical Tension May Be a Necessary Stabilizer. The competition between the US's freedom-oriented, frontier-pushing approach and China's stability-focused, diffusion-driven model creates a complementary tension that could be essential for navigating the "narrow corridor" between AI-driven totalitarianism and uncontrollable chaos.
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November 13, 2025

How Will AI Change Gaming Development? (A Dev’s Take)

The DCo Podcast

AI
Key Takeaways:
  1. Development timelines are collapsing from months to days. AI allows developers to swap entire asset libraries or generate new game concepts at unprecedented speed, turning a two-month art project into a day's work.
  2. The lifespan of any single game is shrinking. Prepare for a world of disposable entertainment. As AI floods the market with content, the strategy will pivot from creating one long-lasting hit to deploying a rapid succession of engaging experiences.
  3. Games are the next evolution of the attention economy. Just as memes became a core tool for community-building around tokens, easily created games will be the next engine for capturing and directing user attention in a hyper-competitive digital world.
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November 11, 2025

AI Nerves, Crypto Realism, Privacy Coins, & Lessons From Trading

1000x Podcast

AI
Key Takeaways:
  1. Adopt a Stock Picker's Mentality. The crypto market is no longer a monolith where a rising tide lifts all boats. Focus on assets with real products, user growth, and cash flow, as the gap between winners and losers will only widen.
  2. Shorting is a Tactical Assault, Not a Siege. Don't "invest" in a short. The only viable short strategies are tactical, targeting specific events like VC unlocks or news-driven spikes. Otherwise, even "total scams" can 5x against you.
  3. Cultivate a Goldfish's Memory. The most critical trading skill is learning how to change your mind. Cut losing trades, forget the loss (but remember the lesson), and redeploy capital without emotional baggage. Stubbornness is a portfolio killer.
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November 11, 2025

Grant Lee: Building Gamma’s AI Presentation Company to 100 Million Users

a16z

AI
Key Takeaways:
  1. Word-of-mouth isn't a feature; it's the engine. Before spending a dime on marketing, obsess over the first 30 seconds of the user experience until people can't help but share it.
  2. Being different is better than being better. Don't build incrementally better slideware. Redefine the core primitives of your category, as Gamma did by moving beyond the 16x9 slide.
  3. Hire painfully slowly to protect your DNA. Resisting the temptation to scale headcount with user growth is a superpower. The goal isn't to hit a hiring target; it's to hire the best people.
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November 7, 2025

Amjad Masad & Adam D’Angelo: How Far Are We From AGI?

a16z

AI
Key Takeaways:
  1. AGI Is a Definitional Debate. Progress toward an AI that can replace a remote worker is happening fast. However, achieving "true" human-like learning efficiency may require an entirely new paradigm beyond scaling current LLMs.
  2. The New Creator Economy Is Code. AI is turning software development into a mainstream creative pursuit, empowering a new class of solo entrepreneurs who can build what previously required entire teams.
  3. Incumbents Learned Their Lesson. Unlike past tech shifts, today's giants are aggressively adopting AI, making it both a sustaining *and* disruptive force. The market is large enough for both incumbents and startups to create massive value.
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November 6, 2025

Mark Zuckerberg & Priscilla Chan: How AI Will Cure All Disease

a16z

AI
Key Takeaways:
  1. Build the Tools, Not Just the House: CZI’s greatest leverage comes from creating open-source tools and datasets. By building the fundamental infrastructure, they empower the entire scientific community—from academic labs to startups—to accelerate discovery.
  2. Data Is the New Microscope: The future of biology hinges on a tight feedback loop between generating novel, purpose-built datasets and training domain-specific AI models on them. This synergy is unlocking insights that were previously impossible.
  3. Virtual Biology Is the Next Frontier: Simulating biology computationally with "virtual cells" will become the new standard for research, enabling scientists to test riskier hypotheses faster and cheaper, dramatically compressing the timeline for major breakthroughs.
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November 5, 2025

Seeing The Future from AI Companions to Personal Software

a16z

AI
Key Takeaways:
  1. The Interface is the Bottleneck. Today's chatbots are the MS-DOS of AI. The next trillion dollars of value will be unlocked not by the models themselves, but by the new "Windows/Mac OS" interface that makes AI accessible and useful for everyone.
  2. Every Creator Will Build Software. The distinction between a content creator and a software developer is collapsing. The next platforms will empower anyone to build mini-apps, turning software into a new medium for community, expression, and monetization.
  3. Ditch the Voice-Only Dream. The Her-inspired fantasy of a screenless, voice-only AI future is a dead end. The winning AI device will be screen-first, built around an AI-native OS that makes software deeply personal and context-aware.
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November 4, 2025

Rollup TV: Aria Protocol, Money Moves Fast EP 8, Crossmint

The Rollup

AI
Key Takeaways:
  1. Culture is the Newest Yield-Bearing Asset: Arya Protocol proves that intellectual property, from music royalties to digital art, can be tokenized into stable, income-generating investments, moving beyond crypto’s speculative roots.
  2. Fintech's Crypto FOMO is Reshaping Finance: The race is on. Traditional payment giants are rapidly adopting stablecoins, not as a gimmick, but as a critical infrastructure upgrade for building faster, cheaper, and more inclusive global financial products.
  3. Money is Becoming Natively Programmable for AI: The future of commerce and finance will be run by AI agents. Stablecoins provide the missing piece—a programmable, automated payment layer that bypasses the friction of traditional banking, unleashing a new wave of economic activity.
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Crypto Podcasts

January 5, 2026

Bitcoin’s Back, Venezuela Regime Change, Memecoins, 2026 Mega Trends

1000x Podcast

Crypto
Key Takeaways:
  1. The Macro Transition: Geopolitical realignment is turning Bitcoin from a speculative asset into a tool of statecraft.
  2. The Tactical Edge: Buy Bitcoin calls dated for late January to capture the $125k target.
  3. The Bottom Line: The next six months will reward those who recognize that the "printing money" era has evolved into a "seizing assets" era.
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January 5, 2026

Inside SharpLink's Massive Ethereum Bet With CEO Joseph Chalom

The Rollup

Crypto
Key Takeaways:
  1. The migration from "Crypto" to "Digital Finance" where the underlying tech becomes invisible.
  2. Audit your protocol's risk disclosures. Prioritize security and third-party code reviews to attract institutional capital.
  3. Ethereum is the leading candidate for the world's financial operating system because it has ten years of zero downtime and a massive validator base.
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January 5, 2026

How the Stablecoin Milkshake will Redollarize the World

Bankless

Crypto
Key Takeaways:
  1. The US is moving from "analog" dollar dominance to a high-velocity digital network that absorbs global liquidity faster than ever.
  2. Maintain exposure to US equities and gold while keeping dollar-denominated cash in short-term bonds to capitalize on the next volatility spike.
  3. The dollar isn't dying; it is being upgraded. Expect the "Milkshake" to suck up global capital as foreign economies struggle with debt and declining growth.
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January 3, 2026

Predictions for 2026

Bell Curve

Crypto
Key Takeaways:
  1. The movement from casino to utility means capital will flow toward protocols with high revenue quality and durability.
  2. Prioritize DeFi products that bridge institutional assets to retail front-ends.
  3. 2026 is the year crypto stops being a promise and starts being a product.
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January 2, 2026

Crypto Only Has 2 Real Business Models | Ejaaz Ahamadeen

The DCo Podcast

Crypto
Key Takeaways:
  1. Value is migrating from raw infrastructure to the model layer. As compute becomes a commodity, the economic winner is the entity that owns the weights and the inference interface.
  2. Audit your portfolio for projects with Visa-style fee structures. Prioritize protocols that generate revenue from external usage rather than internal token circularity.
  3. Sustainable crypto AI requires moving past speculative emissions toward actual service fees. The next year will separate apps that use AI to solve problems from protocols that use AI to sell tokens.
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January 2, 2026

Bittensor Brief #16: Bitsec Subnet 60

Hash Rate Podcast

Crypto
Key Takeaways:
  1. Security is moving from a periodic human service to a continuous machine-verified state.
  2. Stress-test your current security stack by running it against historical exploit benchmarks.
  3. If you are not using AI to defend your code, you are already losing to the AI trying to break it.
See full notes