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AI Podcasts

August 21, 2025

Can AI Fix Housing and Healthcare Affordability?

a16z

AI
Key Takeaways:
  1. AI is the deflationary force for stagnant sectors. While software ate the world, it skipped housing and healthcare. AI is finally tackling the operational drag that has caused costs to balloon for decades.
  2. To solve the housing crisis, make it profitable. The path to more housing supply runs through better returns. By making property operations radically more efficient, AI attracts the capital required to build.
  3. The future of work is human + AI. Automation won't eliminate jobs; it will transform them. As AI handles the administrative grind, human roles will shift to higher-value work like community engagement and complex problem-solving.
See full notes
August 19, 2025

Hash Rate - Ep 129 - Macrocosmos IOTA (sn9) and DataUniverse (sn13)

Hash Rate pod - Bitcoin, AI, DePIN, DeFi

AI
Key Takeaways:
  1. DTO Means Business: Dynamic TAO has forced a Darwinian shift. Subnets must now achieve product-market fit and generate real revenue to survive, transforming from research projects into self-sustaining businesses.
  2. IOTA’s Grand Ambition: IOTA (SN9) isn't just another model trainer; its architecture aims to train trillion-parameter models on decentralized, consumer-grade hardware, directly challenging the dominance of centralized AI labs.
  3. Time to Garden: The protocol's long-term health hinges on active governance. A strong sentiment is emerging to prune low-effort or malicious subnets to focus emissions on projects capable of creating real, lasting value.
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August 19, 2025

Hash Rate - Ep 128 - Ridges ($TAO Subnet 62)

Hash Rate pod - Bitcoin, AI, DePIN, DeFi

AI
Key Takeaways:
  1. AI Is Moving from Copilot to Pilot. Ridges is betting that the future isn't AI assisting humans, but AI replacing them for specific tasks. Their goal is to make hiring a software engineer as simple as subscribing to a service.
  2. Decentralized Economics Are a Moat. By leveraging Bittensor's incentive layer, Ridges outsources a $15M/year R&D budget to a global pool of competing developers, achieving a cost structure and innovation velocity that centralized players cannot match.
  3. The Breakout Subnet Is Coming. Ridges showcases how a Bittensor subnet can solve real-world business problems—privacy, cost, and quality degradation—to build a product that is not just cheaper, but fundamentally better than its centralized counterparts.
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August 18, 2025

Dylan Patel on GPT-5’s Router Moment, GPUs vs TPUs, Monetization

a16z

AI
Key Takeaways:
  1. From Performance to Profit: The AI industry is pivoting from a war of benchmarks to a game of unit economics. Features like GPT-5’s router signal that cost management and monetization are now as important as model capabilities.
  2. Hardware is a Supply Chain Game: Nvidia’s true moat is its end-to-end control of the supply chain. Competitors aren't just fighting a chip architecture; they're fighting a logistical behemoth that consistently out-executes on everything from memory procurement to time-to-market.
  3. The Grid is the Limit: The biggest check on AI’s expansion is the physical world. The speed at which new power infrastructure and data centers can be built will dictate the pace of AI deployment in the US, creating a major advantage for those who can build faster.
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August 18, 2025

Subnet 56 :: Gradients :: Bittensor End-to-end AI Model Training Suite

Opentensor Foundation

AI
Key Takeaways:
  1. Performance is Proven, Not Promised. Gradients isn't just making claims; it’s delivering benchmark-crushing results, consistently outperforming centralized incumbents and producing state-of-the-art models.
  2. Open Source Unlocks the Enterprise. The shift to verifiable, open-source training scripts is a direct solution to customer data privacy concerns, turning a critical vulnerability into a competitive advantage.
  3. The AutoML Flywheel is Spinning. The network's competitive, tournament-style mechanism creates a self-optimizing system that continuously aggregates the best training techniques, ensuring it remains at the cutting edge.
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August 16, 2025

Google DeepMind Lead Researchers on Genie 3 & the Future of World-Building

a16z

AI
Key Takeaways:
  1. **World Models Are a New Modality.** Genie 3 is not just better video; it's an interactive environment generator. This divergence from passive, cinematic models like Veo signals a new frontier focused on agency and simulation, creating a distinct discipline within generative AI.
  2. **Simulation Is the Key to Embodied AI.** The biggest hurdle for robotics is the lack of realistic training environments. Genie 3 tackles this "sim-to-real" gap head-on, providing a scalable way to train agents on infinite experiences before they ever touch physical hardware.
  3. **Emergent Properties Will Drive the Future.** Key features like spatial memory and nuanced physics weren't explicitly coded but emerged from scaling. The next breakthroughs in world models will come from discovering these unexpected capabilities, not just refining existing ones.
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August 15, 2025

Greg Brockman on OpenAI's Road to AGI

Latent Space

AI
Key Takeaways:
  1. AGI is a Compute Game. The primary bottleneck is compute. The process is one of "crystallizing" energy into compute, then into the potential energy of a trained model. More compute means more intelligence.
  2. The Future is a "Manager of Models." AGI won't be a single entity. It will be an orchestrator that delegates tasks to a fleet of specialized models, from fast local agents to powerful cloud reasoners.
  3. Build for Your AI Coworker. To maximize leverage, structure codebases for AI. This means self-contained modules, robust unit tests, and clear documentation—treating the AI as a team member, not just a tool.
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August 15, 2025

The Current Reality of American AI Policy: From ‘Pause AI’ to ‘Build’

a16z

AI
Key Takeaways:
  1. Geopolitics Is the New OS: The AI discourse is no longer an intellectual parlor game about existential risk. It is a strategic mandate driven by fierce competition with adversaries like China.
  2. Open Source Is the Ultimate Moat: The winning strategy isn't to hoard IP but to build an ecosystem. Open source has emerged as the most powerful tool for establishing American models and infrastructure as the global standard.
  3. The Cost of Inaction Exceeds the Risk of Action: The "what's the rush?" argument is dead. The opportunity cost of delaying progress—from curing diseases to solving scientific challenges—is now viewed as a more tangible threat than the theoretical dangers of AI.
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August 15, 2025

Subnet 56 :: Gradients :: Bittensor End-to-end AI Model Training Suite

Opentensor Foundation

AI
Key Takeaways:
  1. **Training is a Solved Problem.** For users and developers, the message is clear: stop building custom training loops. Gradients offers superior performance out-of-the-box, turning the complex art of model training into a simple API call.
  2. **Open Source is the Ultimate Competitive Moat.** By making top training scripts public, Gradients accelerates its own innovation flywheel, creating a continuously compounding advantage that closed-source competitors cannot replicate.
  3. **The Best 8B Model is Now from Bittensor.** Gradients has moved beyond theoretical benchmarks to produce a state-of-the-art model that beats a leading industry player. This is a powerful proof-of-concept for the entire Bittensor ecosystem.
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Crypto Podcasts

October 29, 2025

Deficits Are Forcing the Fed Back Into Expansion | Lyn Alden

Forward Guidance

Crypto
Key Takeaways:
  1. **Fiscal is the new Fed.** Government spending, not central bank policy, is the dominant force in the economy. Stop looking for a traditional recession; the deficit is the stimulus that won’t quit.
  2. **The Fed is re-opening the liquidity spigot.** The era of Quantitative Tightening is over. A gradual but persistent expansion of the Fed's balance sheet is coming, which will provide a tailwind for assets.
  3. **Own scarce assets.** The long-term debasement of fiat currency is the default path. Alden remains constructive on Bitcoin, viewing its current phase as a prelude to a significant move higher in the coming years.
See full notes
October 28, 2025

Hash Rate - Ep 140 - The New Crucible Bittensor Wallet

Hash Rate pod - Bittensor $TAO & Subnets

Crypto
Key Takeaways:
  1. Security Is No Longer an Afterthought: The Crucible Wallet’s native Ledger integration provides the first hardware-secured, consumer-friendly way to manage TAO and subnet tokens, addressing a major security gap in the ecosystem.
  2. Automated Strategy Beats Day Trading: The "Staking to Core Alpha" feature offers a powerful tool that automatically reinvests yield into a customizable portfolio of subnets, saving users from the overwhelming task of constantly researching and reallocating assets.
  3. Capital Flow is King: The wallet's primary mission is to redirect staked TAO from the root network into deserving subnets, providing them with the capital needed to grow and achieve commercial success, which in turn strengthens the entire Bittensor network.
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October 28, 2025

How Crypto Neobanks Work: Frax, Cards, and Visa’s Role

Bankless

Crypto
Key Takeaways:
  1. The Real Metric Is GDP, Not Volume. A million dollars in daily card spending on real-world goods is a far more powerful signal of adoption than hundreds of millions in AMM swap volume. Watch the growth in real economic activity, not just on-chain shuffling.
  2. Infrastructure Is the Bottleneck. The race isn't just to launch another neobank; it's to build the underlying pipes. Protocols like Frax that power multiple stablecoins and neobanks are positioned to capture value from the entire ecosystem's growth.
  3. The End Game Is a Parallel Financial System. Crypto neobanks are the final link needed to close the economic loop. They enable a world where a user can save, earn yield, and spend entirely on-chain, making the concept of a bank account obsolete.
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October 28, 2025

LIVE: EQUITY PERPS, MEGAETH SALE, CRYPTO INTO EOY | 0xResearch

0xResearch

Crypto
Key Takeaways:
  1. Verticalize or Die. Protocols are aggressively bundling services to capture value and own the user experience. Standalone products are at risk of being outcompeted or acquired cheaply, as seen with Pump's acquisition of Padre.
  2. The Middle-Ground ICO is Hot. Highly anticipated projects like MegaETH are finding success with public sales that sit between illiquid private rounds and expensive public listings. For investors with capital, these offer a compelling risk/reward profile.
  3. Performance Trumps Purity. The debate is shifting. While credible neutrality is a good marketing angle, the rise of high-performance chains like Hyperliquid suggests users and capital will flow to the best product, regardless of its decentralization score.
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October 27, 2025

Why Every Major App Will Issue Their Own Stablecoin - m0 CEO

The Rollup

Crypto
Key Takeaways:
  1. Every App is a Future Fintech: Major applications will become their own central banks, issuing native stablecoins to control their financial rails, capture yield, and eliminate the platform risk inherent in relying on third-party issuers.
  2. Infrastructure, Not Brands, is the Real Game: The battle isn't over which stablecoin brand wins, but who builds the underlying rails that make a fragmented ecosystem of thousands of dollars feel like one seamless, interoperable network.
  3. The Stablecoin Market is Just Getting Started: Today's ~$300 billion stablecoin float is a "ridiculously small number." Expect a 100x expansion as money migrates from legacy bank ledgers to programmable, on-chain infrastructure.
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October 27, 2025

Why Pro Athletes Are Betting on Bitcoin, Crypto & Prediction Markets

Bankless

Crypto
Key Takeaways:
  1. Embrace Financial Autonomy: Athletes are adopting crypto not just for gains, but for control. They are tired of a financial system where they are told to "shut your mouth and go play basketball" while trusting strangers with their money.
  2. Regulation is a Two-Front War: The crypto industry must fight defensively to protect wins like stablecoin rewards while also playing offense to ensure new regulations don't stifle DeFi innovation before it can mature.
  3. Prediction Markets are Information Markets: Their true disruption isn't just taking on FanDuel; it's creating a more efficient, decentralized, and transparent way to surface truth in real-time, for everything from sports to politics.
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