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AI Podcasts

November 17, 2025

Emmett Shear on Building AI That Actually Cares: Beyond Control and Steering

a16z

AI
Key Takeaways:
  1. Stop Trying to “Steer” AGI. The control paradigm is a dead end. The goal isn’t a more obedient tool; it’s a trustworthy teammate. We must shift from engineering control to cultivating care.
  2. Alignment is a Process, Not a Product. True alignment isn't a fixed set of rules. It’s a dynamic process of moral learning, akin to raising a child. AIs that only follow rules are brittle and dangerous.
  3. Build for Cooperation, Not Command. The technical path forward involves training AIs in rich, multi-agent environments where they must learn cooperation and theory of mind—the foundational skills for becoming a good member of a group.
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November 16, 2025

Rawson Haverty presents "US & China AI: Lessons from Across the Pacific" | dAGI Summit 2025

Delphi Digital

AI
Key Takeaways:
  1. US Leads in Capital-Intensive Frontier AI; China Excels at Industrial Diffusion. The US leverages deep capital markets for its massive compute buildout and AGI research, while China uses state direction to embed AI into its vast industrial base via open-source models and hardware.
  2. Market Structure Dictates AI Strategy. The US "efficient oligopoly" model prioritizes global dominance and profit reinvestment by a few players. China's "subjugated swarm" model creates intense domestic competition, driving down prices and accelerating adoption at the cost of profitability.
  3. Geopolitical Tension May Be a Necessary Stabilizer. The competition between the US's freedom-oriented, frontier-pushing approach and China's stability-focused, diffusion-driven model creates a complementary tension that could be essential for navigating the "narrow corridor" between AI-driven totalitarianism and uncontrollable chaos.
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November 13, 2025

How Will AI Change Gaming Development? (A Dev’s Take)

The DCo Podcast

AI
Key Takeaways:
  1. Development timelines are collapsing from months to days. AI allows developers to swap entire asset libraries or generate new game concepts at unprecedented speed, turning a two-month art project into a day's work.
  2. The lifespan of any single game is shrinking. Prepare for a world of disposable entertainment. As AI floods the market with content, the strategy will pivot from creating one long-lasting hit to deploying a rapid succession of engaging experiences.
  3. Games are the next evolution of the attention economy. Just as memes became a core tool for community-building around tokens, easily created games will be the next engine for capturing and directing user attention in a hyper-competitive digital world.
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November 11, 2025

AI Nerves, Crypto Realism, Privacy Coins, & Lessons From Trading

1000x Podcast

AI
Key Takeaways:
  1. Adopt a Stock Picker's Mentality. The crypto market is no longer a monolith where a rising tide lifts all boats. Focus on assets with real products, user growth, and cash flow, as the gap between winners and losers will only widen.
  2. Shorting is a Tactical Assault, Not a Siege. Don't "invest" in a short. The only viable short strategies are tactical, targeting specific events like VC unlocks or news-driven spikes. Otherwise, even "total scams" can 5x against you.
  3. Cultivate a Goldfish's Memory. The most critical trading skill is learning how to change your mind. Cut losing trades, forget the loss (but remember the lesson), and redeploy capital without emotional baggage. Stubbornness is a portfolio killer.
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November 11, 2025

Grant Lee: Building Gamma’s AI Presentation Company to 100 Million Users

a16z

AI
Key Takeaways:
  1. Word-of-mouth isn't a feature; it's the engine. Before spending a dime on marketing, obsess over the first 30 seconds of the user experience until people can't help but share it.
  2. Being different is better than being better. Don't build incrementally better slideware. Redefine the core primitives of your category, as Gamma did by moving beyond the 16x9 slide.
  3. Hire painfully slowly to protect your DNA. Resisting the temptation to scale headcount with user growth is a superpower. The goal isn't to hit a hiring target; it's to hire the best people.
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November 7, 2025

Amjad Masad & Adam D’Angelo: How Far Are We From AGI?

a16z

AI
Key Takeaways:
  1. AGI Is a Definitional Debate. Progress toward an AI that can replace a remote worker is happening fast. However, achieving "true" human-like learning efficiency may require an entirely new paradigm beyond scaling current LLMs.
  2. The New Creator Economy Is Code. AI is turning software development into a mainstream creative pursuit, empowering a new class of solo entrepreneurs who can build what previously required entire teams.
  3. Incumbents Learned Their Lesson. Unlike past tech shifts, today's giants are aggressively adopting AI, making it both a sustaining *and* disruptive force. The market is large enough for both incumbents and startups to create massive value.
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November 6, 2025

Mark Zuckerberg & Priscilla Chan: How AI Will Cure All Disease

a16z

AI
Key Takeaways:
  1. Build the Tools, Not Just the House: CZI’s greatest leverage comes from creating open-source tools and datasets. By building the fundamental infrastructure, they empower the entire scientific community—from academic labs to startups—to accelerate discovery.
  2. Data Is the New Microscope: The future of biology hinges on a tight feedback loop between generating novel, purpose-built datasets and training domain-specific AI models on them. This synergy is unlocking insights that were previously impossible.
  3. Virtual Biology Is the Next Frontier: Simulating biology computationally with "virtual cells" will become the new standard for research, enabling scientists to test riskier hypotheses faster and cheaper, dramatically compressing the timeline for major breakthroughs.
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November 5, 2025

Seeing The Future from AI Companions to Personal Software

a16z

AI
Key Takeaways:
  1. The Interface is the Bottleneck. Today's chatbots are the MS-DOS of AI. The next trillion dollars of value will be unlocked not by the models themselves, but by the new "Windows/Mac OS" interface that makes AI accessible and useful for everyone.
  2. Every Creator Will Build Software. The distinction between a content creator and a software developer is collapsing. The next platforms will empower anyone to build mini-apps, turning software into a new medium for community, expression, and monetization.
  3. Ditch the Voice-Only Dream. The Her-inspired fantasy of a screenless, voice-only AI future is a dead end. The winning AI device will be screen-first, built around an AI-native OS that makes software deeply personal and context-aware.
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November 4, 2025

Rollup TV: Aria Protocol, Money Moves Fast EP 8, Crossmint

The Rollup

AI
Key Takeaways:
  1. Culture is the Newest Yield-Bearing Asset: Arya Protocol proves that intellectual property, from music royalties to digital art, can be tokenized into stable, income-generating investments, moving beyond crypto’s speculative roots.
  2. Fintech's Crypto FOMO is Reshaping Finance: The race is on. Traditional payment giants are rapidly adopting stablecoins, not as a gimmick, but as a critical infrastructure upgrade for building faster, cheaper, and more inclusive global financial products.
  3. Money is Becoming Natively Programmable for AI: The future of commerce and finance will be run by AI agents. Stablecoins provide the missing piece—a programmable, automated payment layer that bypasses the friction of traditional banking, unleashing a new wave of economic activity.
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Crypto Podcasts

January 9, 2026

Nic Carter: Quantum Threatens $600B of Bitcoin

Delphi Digital

Crypto
Key Takeaways:
  1. The transition from classical to quantum computing turns static digital gold into a melting ice cube.
  2. Audit your cold storage to ensure you aren't reusing addresses or holding funds in P2PK formats.
  3. Bitcoin’s survival depends on the community’s ability to prioritize insurance over ideological purity before 2030.
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January 9, 2026

Stablecoin Deep Dive with Frax and Transak

The Rollup

Crypto
Key Takeaways:
  1. The transition from DeFi to Neo-Finance where on-chain liquidity meets institutional payment rails.
  2. Prioritize assets that are integrated with payment processors like Stripe or Bridge.
  3. 2026 is the year of the exponential. The winners won't be the high-float L1s but the protocols that function as the economic engine for both lenders and shoppers.
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January 9, 2026

How China Is Quietly Dominating Crypto | Shuyao Kong

The DCo Podcast

Crypto
Key Takeaways:
  1. The next cycle favors teams that combine Western storytelling with Eastern operational intensity.
  2. Monitor the tools and platforms used by high-volume Chinese retail clusters to identify emerging liquidity trends on Solana.
  3. Ignoring the Chinese ecosystem is a choice to remain blind to the market's most active participants.
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January 8, 2026

Why 2026 is The Year of Unification with Sam Kazemian

The Rollup

Crypto
Key Takeaways:
  1. Neo Finance is replacing legacy banking as stablecoins become the TCP/IP packet for all value transfer.
  2. Position in protocols that own their distribution and payment rails rather than those relying on third party liquidity.
  3. The next six months will separate synthetic products from real money as the market rewards end to end utility over isolated DeFi yields.
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January 8, 2026

Hivemind: Will 2026 Be Bullish & Crypto's Token vs Equity Problem

Empire

Crypto
Key Takeaways:
  1. The transition from "governance" to "on-chain equity" is the defining trend for 2025. As regulatory clarity improves, capital will migrate to assets with legally enforceable rights.
  2. Monitor MetaDAO ICOs like Ranger Finance to gauge if retail appetite for "ownership coins" can sustain high valuations. Watch for the first "home run" success story to validate the model.
  3. The next cycle belongs to applications with legally enforceable revenue rights, not L1s with vague utility. Founders who prioritize investor protections will trade at a permanent premium.
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January 8, 2026

Do Buybacks Make Sense? | Lucas Bruder

Lightspeed

Crypto
Key Takeaways:
  1. The transition from opaque block production to verifiable sequencing via tools like BAM and Multiple Concurrent Proposers.
  2. Monitor validator IBRL scores to ensure your transactions aren't being sidelined by yield-chasing leaders.
  3. Solana is maturing into a professional-grade financial layer where execution efficiency is the only sustainable moat for the next 12 months.
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