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AI Podcasts

December 13, 2025

Minimax M2 – Olive Song, MiniMax

AI Engineer

AI
Key Takeaways:
  1. **The "Small is Mighty" Paradigm:** Don't underestimate smaller, specialized models. M2 proves that smart engineering, real-world feedback, and iterative reasoning can outperform larger models in specific, high-value domains.
  2. **Builders, Embrace Iteration:** Design your agents with "interleaved thinking." The ability to self-correct and adapt to noisy environments is critical for real-world utility.
  3. **The "So What?":** The next wave of AI agents will be defined by their robustness, cost-effectiveness, and ability to generalize across dynamic environments. M2 is a blueprint for building practical, scalable AI that developers will actually integrate into their daily workflows.
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December 11, 2025

No Priors Ep. 143 | With ElevenLabs Co-Founder Mati Staniszewski

No Priors: AI, Machine Learning, Tech, & Startups

AI
Key Takeaways:
  1. Strategic Shift: The future of human-computer interaction is voice-first, moving from static content to dynamic, personalized, and agentic experiences.
  2. Builder/Investor Note: Defensibility in AI is increasingly found in deep product layers, specialized architectural breakthroughs (especially in audio), and robust ecosystems, not just raw model scale.
  3. The "So What?": Over the next 6-12 months, expect to see significant advancements in proactive AI agents, immersive media, and personalized education, with voice as the core interface.
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December 10, 2025

The Unicorn Founder Who Delegated Everything.

a16z

AI
Key Takeaways:
  1. The AI-Delegation Revolution is Here: Start experimenting with AI tools like ChatGPT for delegation now. The future involves proactive machine assistants deeply integrated into your workflow.
  2. Builders & Investors: Focus on "How to Delegate": The biggest constraint isn't finding assistants, but teaching clients how to delegate effectively. Tools and services that educate delegators will win.
  3. Reclaim Your Ambition: By offloading the mundane, you free up mental bandwidth to think bigger, pursue more ambitious goals, and ultimately, control your most valuable asset: time.
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December 12, 2025

AI Eats the World: Benedict Evans on the Next Platform Shift

a16z

AI
Key Takeaways:
  1. Strategic Implication: The AI bubble is inevitable. Focus on defensible positions: deep product integration, proprietary data, and distribution, rather than just raw model performance.
  2. Builder/Investor Note: The opportunity lies in productizing AI for specific "jobs to be done" within niche industries, creating intuitive UIs, and building in validation, not just building another foundational model.
  3. The "So What?": We're about to figure out the true "job to be done" for many industries. AI will unbundle existing businesses by exposing their hidden inefficiencies or non-obvious defensibilities.
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December 13, 2025

The Mathematical Foundations of Intelligence [Professor Yi Ma]

Machine Learning Street Talk

AI
Key Takeaways:
  1. Embrace Parsimony and Self-Consistency: Adopt these principles as guiding forces in AI design. Build models that not only compress data efficiently but also maintain a high degree of self-consistency to ensure accurate and reliable world models.
  2. Focus on Abstraction, Not Just Memorization: Prioritize developing systems that can abstract knowledge beyond mere memorization. Move beyond surface-level compression and aim for models that can discover and reason about the underlying principles of the world.
  3. Understand and Reproduce the Brain’s Mechanisms: Focus on understanding and reproducing the mechanisms in the human brain that enable deductive reasoning, logical thinking, and the creation of new scientific theories to truly push AI to the next level.
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December 10, 2025

Nav Kumar: Trishool, AI Alignment, Subnet 23, Mechanistic Interpretability, Rogue LLMs | Ep. 75

Ventura Labs

AI
Key Takeaways:
  1. **Prioritize AI Safety Research:** Invest aggressively in understanding and mitigating AI risks to safeguard humanity against potential rogue LLMs.
  2. **Support Decentralized AI Alignment:** Champion decentralized platforms like Bit Tensor and initiatives like Trishool that promote open and transparent AI alignment research.
  3. **Embrace Mechanistic Interpretability:** Drive the development of tools that enable us to understand and control the internal workings of AI models, ensuring alignment with human values.
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December 10, 2025

Everyone Needs an Assistant. Here’s Why.

a16z

AI
Key Takeaways:
  1. Embrace Delegation as a Foundational Skill: Whether you leverage AI or human support, mastering delegation is paramount for unlocking personal and professional potential.
  2. Prioritize Time Ownership: Recognize time as your most valuable asset and design your life and calendar around your highest goals.
  3. Start Small, Scale Intentionally: Begin with affordable AI tools and gradually incorporate human assistance as your budget and needs evolve, building trust and compounding leverage over time.
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December 8, 2025

Building The Chip That Could Unlock AGI | Naveen Rao

a16z

AI
Key Takeaways:
  1. **Embrace Analog:** Explore and invest in analog computing solutions to overcome the energy limitations of current digital AI systems.
  2. **Prioritize Causality:** Shift focus towards AI models that incorporate time and causality, potentially unlocking more advanced and human-like intelligence.
  3. **Support Hardware Innovation:** Invest in and foster startups like Unconventional AI that are tackling fundamental challenges in AI hardware.
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December 8, 2025

Why AI Will Have To Run On Blockchains

The DCo Podcast

AI
Key Takeaways:
  1. Blockchain is essential for AI to ensure censorship resistance and uninterrupted accessibility.
  2. Trustworthy AI agents require on-chain governance to manage assets securely and transparently.
  3. AI agents can drastically accelerate blockchain adoption and optimize corporate processes.
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Crypto Podcasts

March 7, 2025

Strategic Bitcoin Reserve, Crime, and the Ethereum Foundation | Weekly Roundup

Empire

Crypto

Key Takeaways:

  • 1. The potential establishment of a U.S. Strategic Bitcoin Reserve could signal a significant shift in government policy towards crypto, with implications for market stability and regulatory clarity.
  • 2. Transparency and ethical practices in crypto are under scrutiny, with calls for standardized disclosures to prevent market manipulation and build trust.
  • 3. The Ethereum Foundation's restructuring efforts highlight the challenges of maintaining core values while addressing operational inefficiencies.
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March 7, 2025

What Trump's Crypto Reserve, Tariffs, & White House Summit Mean for Markets

Bankless

Crypto

Key Takeaways:

  • 1. Trump's crypto reserve announcement highlights the potential for political influence in crypto markets, but practical implementation remains uncertain.
  • 2. The reintroduction of tariffs under Trump is causing market volatility and raising concerns about economic growth and international relations.
  • 3. Ethereum faces pressure to scale its layer one to remain competitive, with leadership changes and new technologies offering potential paths forward.
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March 7, 2025

Macro Trends, Trump’s Evolving Crypto Strategy, and Aave’s New Proposal | Roundup

Bell Curve

Crypto

Key Takeaways:

  • 1. The crypto market is increasingly influenced by macroeconomic trends, requiring a shift in strategy from short-term gains to long-term resilience.
  • 2. The Trump administration's crypto strategy could reshape the U.S. as a global crypto hub, with significant policy implications.
  • 3. Aave's buyback proposal highlights a trend towards integrating traditional financial strategies in crypto, aiming for sustainable growth.
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March 7, 2025

A Solana Data Deep Dive With Carlos Gonzalez Campo

Lightspeed

Crypto

Key Takeaways:

  • 1. The SIMD 96 update has increased inflation and highlighted the need for better alignment between validators and stakers.
  • 2. Pump.fun's move to create its own AMM poses a significant challenge to Radium, which must innovate to maintain its market position.
  • 3. While meme coins drive significant activity, Solana's growing stablecoin supply suggests a robust foundation for future development.
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March 7, 2025

Amanda Cassatt on Crypto’s Branding Problem, Scaling Serotonin, and Yapping

The Rollup

Crypto

Key Takeaways:

  • 1. Crypto projects must prioritize genuine market needs and avoid hype-driven strategies to achieve long-term success.
  • 2. Empowering senior leaders and fostering a culture of trust and delegation are crucial for scaling a marketing firm like Serotonin.
  • 3. Token launches should focus on engaging committed holders and navigating the evolving regulatory landscape to ensure sustainability.
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March 6, 2025

Beyond Bitcoin: What Tokens Should Be in the U.S. Crypto Reserve?

Unchained

Crypto

Key Takeaways:

  • 1. Bitcoin and Ethereum are prime candidates for a U.S. crypto reserve due to their size and decentralization.
  • 2. The U.S. must address regulatory clarity to retain and attract top crypto talent.
  • 3. Prioritizing U.S.-made crypto assets can bolster domestic innovation and maintain technological leadership.
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