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AI Podcasts

December 20, 2025

Are AI Benchmarks Telling The Full Story? [SPONSORED]

Machine Learning Street Talk

AI
Key Takeaways:
  1. Strategic Shift: The market will increasingly demand AI models evaluated on human-centric metrics, not just technical benchmarks. Companies prioritizing user experience and safety will gain a competitive edge.
  2. Builder/Investor Note: Investigate companies developing or utilizing advanced, demographically representative human evaluation frameworks. These are crucial for building defensible, user-aligned AI products.
  3. The "So What?": Over the next 6-12 months, expect a growing focus on AI safety, ethical alignment, and nuanced human preference data. The "Wild West" of AI evaluation is ending, paving the way for more robust, trustworthy systems.
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December 17, 2025

Rethinking Pre-Training for Agentic AI [Aakanksha Chowdhery] - 759

The TWIML AI Podcast with Sam Charrington

AI
Key Takeaways:
  1. Strategic Implication: The next frontier in AI is agentic, and progress hinges on fundamental pre-training innovation, not just post-training optimizations.
  2. Builder/Investor Note: Focus on teams with deep experience in scaling and debugging large models, as this is a high-capital, high-risk endeavor. Builders should prioritize developing new benchmarks for agentic capabilities.
  3. The "So What?": The industry needs to move beyond next-token prediction and static benchmarks to unlock truly capable, self-correcting AI agents in the next 6-12 months.
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December 17, 2025

Code World Model: Building World Models for Computation – Jacob Kahn, FAIR Meta

AI Engineer

AI
Key Takeaways:
  1. Shift in AI Development: The focus moves from syntax-aware code generation to execution-aware reasoning, enabling more robust and intelligent code agents.
  2. Builder/Investor Note: Prioritize tools and platforms that support explicit execution modeling and highly asynchronous, high-throughput RL training for agentic systems.
  3. The "So What?": AI that can simulate complex systems internally will drastically reduce development and testing costs, accelerating innovation in software and distributed systems over the next 6-12 months.
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December 17, 2025

AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs

AI Engineer

AI
Key Takeaways:
  1. Strategic Shift: AI-driven kernel generation is not replacing human genius but augmenting it, allowing experts to focus on novel breakthroughs while AI automates the application of known optimizations across a complex hardware landscape.
  2. Builder/Investor Note: Focus on robust validation and hardware-in-the-loop systems. Claims of "AI inventing new algorithms" in this domain are premature. The real value is in automating the "bag of tricks" for heterogeneous compute.
  3. The "So What?": This technology is critical for scaling agentic AI workloads. Expect significant investment in tools that abstract hardware complexity and enable efficient, automated optimization, driving down the cost of AI inference in the next 6-12 months.
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December 18, 2025

AI Consulting in Practice – NLW, Super ai

AI Engineer

AI
Key Takeaways:
  1. The Agent Economy is Here: Enterprises are moving past pilots with AI agents. Builders should focus on orchestration layers and human-agent interaction design.
  2. ROI Measurement is the Next Frontier: Investors should look for solutions that help organizations accurately track and attribute AI value beyond traditional metrics.
  3. Strategic AI, Not Spot Solutions: The biggest wins come from systematic, cross-organizational AI strategies that target new capabilities and revenue growth, not just incremental time savings.
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December 18, 2025

How to build an AI native company (even if your company is 50 years old) – Dan Shipper, Every

AI Engineer

AI
Key Takeaways:
  1. The 100% AI adoption threshold is a step-function change, not incremental. Companies that commit fully will outpace those with partial integration.
  2. Builders should prioritize "compounding engineering" by codifying knowledge into reusable prompts. This builds an organizational memory that accelerates future development exponentially.
  3. Re-evaluate team structures and roles. Single engineers can own complex products, and even technical managers can contribute code, shifting how organizations operate.
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December 17, 2025

“How We Can Eliminate Crime” | Ben Horowitz and Garrett Langley

a16z

AI
Key Takeaways:
  1. Effective crime reduction requires a shift from reactive punishment to proactive, intelligence-driven deterrence, making it highly probable for criminals to be caught.
  2. The market for AI-powered public safety technology, particularly solutions that integrate data for precision and accountability, presents a significant opportunity. Public-private partnerships are a key funding mechanism.
  3. Over the next 6-12 months, expect to see more cities adopt advanced surveillance and AI tools, driven by private funding, as they seek to improve safety and address staffing shortages without resorting to ineffective, broad-stroke policies.
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December 18, 2025

Two Futures | Runtime 2025

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next decade will be defined by who builds the core infrastructure for intelligence. This is where the most significant value and influence will accrue.
  2. Builder/Investor Note: Direct capital and talent towards foundational AI components—chips, models, and interoperable systems. Avoid the temptation to only build at the application layer.
  3. The So What?: The window for shaping the future of intelligence is now. Engage in the deepest, most complex challenges to secure a footprint in this new era.
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December 18, 2025

The EU and the not-so-simple macroeconomics of AI – Luis Garicano

Epoch AI

AI
Key Takeaways:
  1. Strategic Implication: The global AI race is a zero-sum game for foundational models. Europe's best strategy is a "smart second mover" approach, focusing on the implementation layer by ensuring interoperability and data portability.
  2. Builder/Investor Note: Invest in AI that achieves true autonomy and enhances expert productivity. Be wary of markets stifled by over-regulation, which can impede AI adoption and growth.
  3. The "So What?": Europe faces a critical juncture. Without embracing AI-driven growth, its demographic and debt problems will worsen, leading to higher interest rates without the corresponding economic expansion.
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Crypto Podcasts

March 11, 2025

How Baxus Is Bringing Whiskey Onchain | Tzvi Wiesel

Lightspeed

Crypto

Key Takeaways:

  • 1. Baxus is transforming the spirits market by leveraging blockchain to streamline distribution and enhance transparency.
  • 2. The platform's innovative use of NFTs and DeFi protocols offers new financial opportunities for collectors and businesses.
  • 3. Baxus exemplifies how blockchain can solve real-world problems, providing a model for future crypto applications.
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March 11, 2025

Rich Rines on Bitcoin's Path to $1,000,000

The Rollup

Crypto

Key Takeaways:

  • 1. Institutional interest is driving the development of structured financial products for Bitcoin, enhancing its legitimacy and adoption.
  • 2. Bitcoin's design as a secure, slow asset is a strategic advantage, positioning it as a leading collateral asset in the global financial system.
  • 3. The future of Bitcoin lies in horizontal scaling and innovative financial products, with the potential to significantly impact the broader crypto ecosystem.
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March 10, 2025

Can Frontends Act as a Moat? | Josh Litchman & Tolks

0xResearch

Crypto

Key Takeaways:

  • 1. The crypto market is maturing, with a shift towards fundamentals and defensive tokens gaining prominence.
  • 2. Frontends are crucial in capturing and retaining users, acting as a strategic moat in the competitive crypto landscape.
  • 3. Crypto gaming is evolving, with casual games offering new opportunities for user engagement and economic experimentation.
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March 9, 2025

Is The Bottom In?

Steady Lads Podcast

Crypto

Key Takeaways:

  • 1. The crypto market is undergoing a correction, with significant volatility and mixed sentiment about future directions.
  • 2. Political figures are influencing crypto markets, but their involvement is often seen as unpredictable and potentially destabilizing.
  • 3. Binance's actions against market manipulation may signal a shift towards more stable and fundamental-driven market conditions.
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March 26, 2025

Why Institutions Are Bullish With Eric Peters

Empire

Crypto

Key Takeaways:

  1. The politicization of markets will continue to drive volatility and uncertainty, making crypto an attractive alternative asset class.
  2. Institutional adoption is gaining momentum, with sovereign wealth funds, pensions, and endowments poised to increase their allocations to crypto.
  3. The tokenization of everything is coming, creating massive opportunities within the crypto ecosystem.
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March 26, 2025

Will We See A Solana ETF In 2025? | Matthew Sigel

Lightspeed

Crypto

Key Takeaways:

  1. Institutional interest in Bitcoin is growing, but Solana and other altcoins face headwinds from low institutional adoption, regulatory uncertainty, and a challenging macroeconomic environment.
  2. A Solana ETF is highly probable by late 2025, pending regulatory approvals and assuming the SEC addresses outstanding questions.
  3. Growth in stablecoin usage and its impact on fee revenue for SOL holders is crucial for driving future institutional adoption of Solana.
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