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AI Podcasts

February 3, 2026

Inside The Biggest Uranium Deal In 50 Years | Scott Nolan, CEO of General Matter

The Generalist

AI
Key Takeaways:
  1. Geopolitical tensions and the insatiable energy demands of the AI revolution are forcing a re-evaluation of national energy security.
  2. Invest in companies applying "first principles" engineering and a commercial cost-reduction mindset to foundational, capital-intensive industries.
  3. The US nuclear fuel supply chain is undergoing a rapid, government-backed revitalization.
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February 3, 2026

OpenClaw Makes AI Agents and CPUs Get Real

Semi Doped

AI
Key Takeaways:
  1. The macro trend of autonomous AI agents is shifting compute demand beyond GPUs, creating an unexpected CPU crunch and forcing a re-evaluation of on-premise inference and cost-optimized model routing for security and efficiency.
  2. Investigate hybrid compute strategies, combining secure local environments (Mac Minis, home servers) with cloud-based LLMs, and explore multi-model API gateways like OpenRouter to optimize agent costs and performance.
  3. AI agents are here, demanding a rethink of your compute stack and security protocols. Prepare for a future where CPU capacity, not just GPU, becomes a critical bottleneck, and strategic cost management for diverse AI models is non-negotiable for competitive advantage.
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February 4, 2026

⚡️ Context graphs: AI’s trillion-dollar opportunity — Jaya Gupta, Ashu Garg, Foundation Capital

Latent Space

AI
Key Takeaways:
  1. The move from general-purpose LLMs to specialized AI agents demands a new data architecture that captures the *why* of decisions, not just the *what*. This creates a new, defensible layer of institutional memory, moving value from raw model IP to proprietary decision intelligence.
  2. Invest in or build agentic systems that are in the *orchestration path* of specific business processes. This allows for the organic capture of decision traces, forming a proprietary context graph that incumbents cannot easily replicate.
  3. Over the next 12 months, the ability to build and extract value from context graphs will define the winners in the enterprise AI space, creating a new "context graph stack" that will be 10x more valuable than the modern data stack.
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February 2, 2026

We Entered an Era Where No One Knows What Comes Next

Turing Post

AI
Key Takeaways:
  1. AI's progress has transitioned from a linear, bottleneck-driven model to a multi-layered, interconnected explosion of advancements. This makes traditional long-term forecasting obsolete.
  2. Prioritize building and investing in adaptable systems and teams that can rapidly respond to emergent opportunities across diverse AI layers. Focus on robust interfaces and composability rather than betting on a single "next frontier."
  3. The next 6-12 months will test our ability to operate in an environment where the future is increasingly opaque. Success will come from embracing this unpredictability, focusing on present opportunities, and building for resilience against an unknowable future.
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February 2, 2026

Ben Horowitz & David Solomon on Why Scale Is The Only Thing That Matters

a16z

AI
Key Takeaways:
  1. The Macro Shift: Unprecedented fiscal and monetary stimulus, combined with an AI-driven capital investment super cycle, creates a "sweet spot" for financial assets and growth technology. This favors institutions with scale and adaptability.
  2. The Tactical Edge: Prioritize investments in companies with proprietary data and significant GPU access, as these are new competitive moats in the AI era. For founders, secure capital to compete against well-funded incumbents.
  3. The Bottom Line: Scale and strategic capital deployment are paramount. Whether a financial giant or tech insurgent, the ability to grow, adapt to AI's new rules, and handle regulatory currents will determine relevance and success.
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February 1, 2026

Google’s AI Stack Is Unmatched (No One Else Is Even Close) w/ Ejaaz

Milk Road AI

AI
Key Takeaways:
  1. The AI industry is consolidating around players with deep, proprietary data and infrastructure, transforming general LLMs into personalized, transactional agents. This means value accrues to those who can not only build powerful models but also distribute them at scale and integrate them into daily life.
  2. Investigate companies building on top of Google's AI ecosystem or those creating niche applications that use personalized AI. Focus on solutions that move beyond simple chatbots to actual task execution and intent capture.
  3. Google's strategic moves, particularly with Apple and in e-commerce, signal a future where AI is deeply embedded in every digital interaction. Understanding this shift is crucial for identifying where value will be created and captured.
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January 31, 2026

State of AI in 2026: LLMs, Coding, Scaling Laws, China, Agents, GPUs, AGI | Lex Fridman Podcast #490

Lex Fridman

AI
Key Takeaways:
  1. The AI industry is pivoting from a singular AGI pursuit to a multi-pronged approach, where specialized models, advanced post-training, and geopolitical open-source competition redefine competitive advantage and talent acquisition.
  2. Invest in infrastructure and expertise for advanced post-training techniques like RLVR and inference-time scaling, as these are the primary drivers of capability gains and cost efficiency in current LLM deployments.
  3. The next 6-12 months will see continued rapid iteration in AI, driven by compute scale and algorithmic refinement rather than architectural overhauls. Builders and investors should focus on specialized applications, human-in-the-loop systems, and the strategic implications of open-weight models to capture value in this evolving landscape.
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January 31, 2026

Inside a Chinese AI Lab: How MiniMax Builds Open Models

Turing Post

AI
Key Takeaways:
  1. The open-source AI movement is democratizing access to powerful models, but this decentralization shifts the burden of safety and robust environmental adaptation from central labs to individual builders.
  2. Prioritize investing in or building tools that provide robust, scalable evaluation and alignment frameworks for open-weight models.
  3. The next 6-12 months will see a race to solve environmental adaptability and human alignment in open-weight agentic AI. Success here will define the practical utility and safety of the next generation of AI applications.
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February 1, 2026

Google’s AI Stack Is Unmatched (No One Else Is Even Close) w/ Ejaaz

Milk Road AI

AI
Key Takeaways:
  1. Data is the New Moat, and Google Owns the Farm
  2. Apple's Billion-Dollar Bet on Gemini
  3. Google's Intent to Own E-commerce and Personal AI
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Crypto Podcasts

April 4, 2025

Are Stablecoins the only good crypto use case?

blocmates.

Crypto
Key Takeaways:
  1. Stablecoins Reign: Forget moonshots; stablecoins are crypto's clearest win, providing real-world utility and attracting both corporate giants (Tether, Circle) and even government attention.
  2. Macro Still Matters (Kind Of): While extreme tariff news rocked traditional markets, crypto's reaction was comparatively muted – expect continued volatility, but perhaps less direct correlation than stocks anticipate.
  3. Watch Stablecoin Ecosystem Plays: While Tether and Circle dominate headlines, the narrative strength around stablecoins could create opportunities for related on-chain protocols (like Ethena, Maker) post-macro cooldown.
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April 4, 2025

Why Dan Romero built Farcaster, a decentralized social network #crypto #web3 #farcaster #eth #sol

Bankless

Crypto
Key Takeaways:
  1. Decentralized Social, Realized: Farcaster offers a tangible example of an "at-scale" decentralized social network built on crypto rails (initially Ethereum).
  2. Unlocking Social Data: The core innovation is the open, permissionless protocol, giving developers API access to build diverse applications on a shared social dataset.
  3. Beyond Cloning: While the first app looks familiar (Twitter-like), the underlying protocol enables vastly different social applications, from niche integrations to entirely new platform paradigms.
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April 3, 2025

The Trump Tariff Dump

1000x Podcast

Crypto
Key Takeaways:
  1. Buy the Fear (Selectively): Target Bitcoin dips aggressively in the $73k-$78k zone for mid-term holds, anticipating a potential reversal once tariff fears subside.
  2. Short the Weakness: Ethereum presents a compelling short opportunity targeting $1500 or lower; most altcoins remain vulnerable until market sentiment improves.
  3. Trade Nimbly, Hedge Wisely: This market rewards quick profit-taking on bounces and punishing overstayed welcomes. Use put options to hedge against unpredictable downside moves in this "once-in-80-year" tariff scenario.
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April 2, 2025

1000x "Liberation Day" Livestream

1000x Podcast

Crypto
Key Takeaways:
  1. Brace for Impact, Watch for Stimulus: Tariffs likely guarantee short-term economic pain and recession risk, but expect swift policy responses (tax cuts) if things get too dire.
  2. Bitcoin > Alts (Mostly): Prioritize Bitcoin exposure due to relative strength. Altcoins (especially ETH) face severe headwinds; shorting weak names is viable. Keep an eye on the RWA narrative.
  3. Trade the Extremes: Volatility is the game. Buy deep fear ($73-78k BTC zone), sell rips quickly, stay nimble, and don't overexpose yourself without hedges.
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April 2, 2025

A New Era of Global Capital: How Blockchains Can Fix Broken Finance

Bankless

Crypto
Key Takeaways:
  1. Finance is Moving On-Chain: The future isn't siloed databases using the internet for messaging; it's financial ledgers living on unified, open-access blockchains – the true Internet Financial System.
  2. Strong Property Rights, Stronger Economies: Blockchains provide globally accessible, technologically enforced property rights, bypassing weak local legal systems and unlocking trillions in capital – a massive driver for global development.
  3. Crypto Grows Up: The era of pure speculation and inert protocols is fading; sustainable businesses, real cash flows, and robust token holder rights are the new requirements for success and investment.
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April 1, 2025

Tim Beiko: What are the biggest misconceptions around Ethereum? #crypto #eth #ethereum #podcast

Bankless

Crypto
Key Takeaways:
  1. Timelines are Fluid Until Scheduled: Don't treat estimated Ethereum upgrade windows discussed early in development as hard deadlines; "delays" only truly occur after a specific date is set and missed.
  2. Communication is Hard: Core developers wrestle with how much certainty to project about timelines, balancing the need for transparency against the risks of premature commitment or unhelpful vagueness.
  3. Manage Expectations: Observers and investors should factor the inherent uncertainty of deep R&D into their expectations regarding Ethereum upgrade timelines.
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