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AI Podcasts

May 30, 2025

SN17 - 404GEN :: Decentralized AI generated 3D assets

Opentensor Foundation

AI
Key Takeaways:
  1. Unlocking Creative Potential: 404GEN radically lowers barriers to 3D content creation, enabling faster iteration and new forms of interactive media previously unfeasible for smaller teams or individuals.
  2. Gaussian Splats are Ascendant: This representation is emerging as a powerful alternative for 3D AI, and 404GEN is at the forefront of its practical application and tooling.
  3. BitTensor's Competitive Edge Shines: The subnet's rapid quality improvement and the innovative ELO validation system highlight BitTensor's power to incentivize and coordinate decentralized intelligence towards state-of-the-art results.
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May 30, 2025

Hey Tech, Come to Healthcare

a16z

AI
Key Takeaways:
  1. **Build for Behavior Change:** The biggest wins will come from engaging consumers and enabling sustainable health behaviors, an area where tech excels.
  2. **AI is the Leapfrog:** Healthcare can jump directly to AI-driven solutions, bypassing clunky legacy software, especially for service-oriented tasks.
  3. **The Trillion-Dollar Prize is Real:** Whether through full-stack "payvider" models or horizontal platforms, the path to becoming the world's largest company runs through transforming the consumer healthcare experience.
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May 29, 2025

Building a DePIN-powered Shazam for Media with Rumi | Niko Cunningham and Mateusz Poreda

Proof of Coverage Media

AI
Key Takeaways:
  1. **Decentralized Analytics:** Rumi’s DePIN model democratizes media intelligence, offering far richer and more granular data than traditional players like Nielsen.
  2. **Context is King:** The "Shazam for media" capability will fuel a new generation of AI agents and interactive experiences, making media deeply engaging.
  3. **Investor Signal:** The $5M pre-seed (EV3, A16Z CSX) and early traction with industry players like Tivision validate Rumi's approach and market potential.
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May 29, 2025

Beyond Leaderboards: LMArena’s Mission to Make AI Reliable

a16z

AI
Key Takeaways:
  1. Reliability Demands Real-Time, Human-Centric Testing: Static benchmarks are dead. AI reliability for complex tasks requires continuous evaluation based on diverse, subjective human preferences in real-world scenarios.
  2. Crowd-Sourced Evaluation Outperforms Insular Expertise: The "wisdom of the crowd," as captured by LMArena, provides a more robust and representative measure of AI performance than siloed expert opinions, preventing narrow value-encoding.
  3. Personalized Evaluation is the Next Frontier: Technologies like "Prompt to Leaderboard" show the potential for highly granular, cost-effective, and personalized AI model selection, maximizing utility for individual users and specific tasks.
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May 28, 2025

Rick Rubin: Vibe Coding is the Punk Rock of Software

a16z

AI
Key Takeaways:
  1. Embrace AI as a Co-Creator: Leverage AI to democratize creation and rapidly iterate, but remember the unique human element—your distinct point of view and intuition—is irreplaceable.
  2. Authenticity Over Algorithm: Whether you're an artist or an entrepreneur, genuine connection comes from unwavering commitment to your core vision, not by chasing fleeting trends or assumed audience desires.
  3. Question Everything, Especially "Answers": Cultivate a mindset of curiosity and critical thinking. AI can provide answers, but true insight comes from deeply engaging with questions and understanding that knowledge is ever-evolving.
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May 27, 2025

7 More Healthy Years: What We Can Learn from Super Agers

a16z

AI
Key Takeaways:
  1. Embrace AI-Powered Prevention: AI's capacity to synthesize vast health data will redefine personalized risk assessment and early intervention, moving us beyond one-size-fits-all healthcare.
  2. Target the "Big Three" Early: Focus on preventing cancer, cardiovascular disease, and neurodegenerative conditions by leveraging their long incubation periods for proactive interventions.
  3. Leverage New Therapeutic Frontiers: Groundbreaking drug classes like GLP-1s and rapid advancements in immunotherapy offer unprecedented tools to combat and, crucially, prevent major diseases.
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May 27, 2025

TAOFU's Mikel & Mitch: Enabling Capital Formation for Subnets on Bittensors $10B+ Network

Delphi Digital

AI
Key Takeaways:
  1. Democratized Subnet Funding: TAOFU’s SNS model allows subnet creators to raise capital without diluting their core emission-earning potential, fostering more shots on goal for AI innovation on Bittensor.
  2. Investor Access & Liquidity: For investors, TAOFU provides a clear mechanism (SNS tokens and an integrated DEX) to invest in early-stage Bittensor subnets and gain liquidity, previously a closed-off and opaque process.
  3. Curated Quality: TAOFU’s permissioned approach and focus on sustainable value capture (with plans for a curator model) aim to filter for high-quality projects, protecting investors while nurturing promising AI ventures within Bittensor.
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May 26, 2025

Has AI Revived the DePIN Sector? | Dmitriy Berenzon

0xResearch

AI
Key Takeaways:
  1. AI is DePIN's Demand Catalyst: The need for affordable AI compute is breathing new life and tangible demand into decentralized infrastructure.
  2. Value Accrual & Revenue are King: For DePIN tokens to thrive in liquid markets, clear mechanisms for value flow-through from opco revenue to the token are non-negotiable; "ARR is the new TVL."
  3. Distribution Trumps Decentralization (for now): Crypto-native solutions, especially in payments, must crack the distribution code or risk being outmaneuvered by Web2 incumbents leveraging their massive user bases.
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May 26, 2025

Chatbot platforms might replace social media

Machine Learning Street Talk

AI
Key Takeaways:
  1. AI Companionship is Exploding: Millions are already deeply engaged with AI for emotional connection, and this is just the beginning as technology like GPT-4o normalizes it.
  2. Lean Engineering Can Win: Chai's success with a tiny, hyper-talented team and innovative techniques like model blending proves that massive VC-backed operations aren't the only path to scale in AI.
  3. The Next Social Platform Might Be AI: As AI offers more active, personalized, and consequence-free social interaction, it could very well become the dominant way people connect, potentially supplanting traditional social media.
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Crypto Podcasts

April 28, 2025

Crypto's Fastest Growing App: Is Pumpfun's Revenue Sustainable?

Lightspeed

Crypto
Key Takeaways:
  1. Revenue Reality Check: Pumpfun's impressive revenue warrants investigation; sustainability is questionable if heavily reliant on bot activity or if it operates like a high-loss "casino" for users.
  2. Platform Duality: Pumpfun serves as both a backend launchpad discovered via external platforms and a direct trading venue, with ~70% of pre-launch volume happening on-site.
  3. High-Risk Environment: The platform operates like a "less fair casino," meaning users should anticipate significant risk and potential for loss.
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April 28, 2025

Do VC tokens actually have value, or are they leaching off retail investors?

The Gwart Show

Crypto
Key Takeaways:
  1. Potential has Price: Markets value the option for a token to capture future cash flows, not just current ones. Dismissing tokens without active fees is shortsighted.
  2. Fee Activation Isn't Genesis: Turning on token fees typically causes a moderate price bump (15-20%), proving the market already factored in this possibility.
  3. Governance is Power: The right to govern, including the right to implement future economics, constitutes a tangible source of value recognized by the market.
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April 26, 2025

IT IS EARLY IN CRYPTO! #complaints #funny #haha #bitcoin

Unchained

Crypto
Key Takeaways:
  1. **User Education is Paramount:** The biggest immediate "consumer protection" gap revealed isn't faulty platforms (based on these complaints), but users not understanding the tech they're using.
  2. **Blockchain Basics Aren't Basic Yet:** Immutability, custody, and risk management in crypto are poorly understood concepts driving user frustration and complaints.
  3. **Regulatory Focus vs. Reality:** The CFPB shifting focus might be less impactful if current user problems stem more from knowledge gaps than addressable company actions.
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April 25, 2025

Zora and the Future of Crypto Media | Weekly Roundup

Bell Curve

Crypto
Key Takeaways:
  1. Valuation is Relative: Forget pure fundamentals; focus on what's priced in and relative value, normalizing metrics for comparison.
  2. Creator Economy Shift: Crypto platforms like Zora prioritize creator earnings, potentially sacrificing platform revenue for user growth – a different value capture model than Web2.
  3. Financializing Everything: Tokenization extends market price discovery beyond finance to information and content, potentially creating powerful new discovery and monetization mechanisms.
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April 25, 2025

Zora & The Future Of Crypto Media | Weekly Roundup

Empire

Crypto
Key Takeaways:
  1. Focus on Flow: Prioritize protocols demonstrating tangible cash flow generation and distribution to token holders (e.g., Maker, Hyperliquid) for fundamental value plays.
  2. Creator is King (Economically): Crypto fundamentally alters creator economics; platforms distributing significant value back (like Zora aims to) will attract talent, disrupting incumbents even if the platform token itself doesn't capture massive value.
  3. Price Discovery Expands: Crypto lowers the friction for asset issuance, enabling market-based price discovery to move beyond finance into information and content itself – a powerful, disruptive force.
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April 25, 2025

Is Zora Crypto's Breakout SocialFi Moment? | Weekly Roundup

Lightspeed

Crypto
Key Takeaways:
  1. Transparency is Non-Negotiable: Zora's chaotic token launch proves clear communication and transparent mechanics are crucial for project legitimacy and user safety.
  2. Tokenomics Matter: Launching "for fun" tokens while allocating heavily to insiders erodes trust in an already skeptical market; utility or clear value propositions are needed.
  3. Fix The Game: Rampant bot sniping on launchpads like Pump.fun undermines fairness; innovations like Zora's Doppler AMM are vital experiments to level the playing field.
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