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AI Podcasts

February 3, 2026

Why The Laws of Startup Physics Have Changed | Ben Horowitz Interview

Invest Like The Best

AI
Key Takeaways:
  1. The Macro Shift: AI is collapsing the time horizon for technological deployment and market dominance, shifting the competitive advantage from pure innovation to a combination of innovation, capital, and rapid infrastructure deployment.
  2. The Tactical Edge: Invest in companies that are not just building AI, but are fundamentally rethinking existing industries with AI-first principles, recognizing that traditional software moats are eroding.
  3. The Bottom Line: The next 12-24 months will see AI's broad impact kick in, creating unprecedented opportunities for those who understand its new "laws of physics" and the critical role of policy in shaping its trajectory.
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February 4, 2026

Ozempic Won't Solve America's Obesity Problem

a16z

AI
Key Takeaways:
  1. The healthcare system is moving from reactive, acute care to proactive, preventative interventions, driven by the unsustainable costs of chronic disease and a growing understanding of environmental health.
  2. Build infrastructure that financially incentivizes lifestyle interventions, such as TrueMed's HSA/FSA payment rails for health-promoting products and services.
  3. The next decade will see hundreds of billions of dollars redirected towards preventative health. Companies that bridge the gap between lifestyle choices and healthcare financing will capture significant market share.
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February 3, 2026

SpaceX Engineer Explains America's Biggest Energy Mistake | Scott Nolan, CEO of General Matter

The Generalist

AI
Key Takeaways:
  1. The Macro Shift: Global energy demand, driven by AI, forces a strategic re-evaluation of nuclear power. This creates a window for nations to re-shore critical energy infrastructure, moving from reliance on adversaries to domestic, cost-competitive solutions.
  2. The Tactical Edge: Investigate companies addressing foundational supply chain gaps in critical industries like energy. Look for teams with a "first principles" engineering approach and a track record of commercializing hard tech.
  3. The Bottom Line: America's energy independence and its ability to power future technological growth, like AI, hinge on rebuilding domestic nuclear fuel enrichment. This is not just an industrial opportunity; it is a national security imperative.
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February 4, 2026

The Economic Singularity Will Make Today’s Economy Unrecognizable w/ Dr. Alexander Wissner-Gross

Milk Road AI

AI
Key Takeaways:
  1. The Macro Shift: AI-driven hyperdeflation is colliding with the technical reality of autonomous AI agents creating their own crypto-backed economies, threatening a decoupling from human fiat systems.
  2. The Tactical Edge: Investigate and build infrastructure that bridges human and AI economies, focusing on fiat-to-crypto rails that can accommodate agent-driven transactions to prevent a complete split.
  3. The Bottom Line: The next 5-10 years will see an unprecedented economic transformation. Understanding AI's deflationary power and the emerging AI agent economy is critical for navigating a world where traditional economic models may no longer apply.
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February 3, 2026

OpenClaw Makes AI Agents and CPUs Get Real

Semi Doped

AI
Key Takeaways:
  1. The time of practical AI agents is here, moving compute demand beyond pure GPU inference to a significant reliance on CPUs for coordination, data handling, and security.
  2. Evaluate your agent deployment strategy now, prioritizing sandboxed environments (VPS, dedicated local servers) and exploring cost-optimized model routing to manage API expenses.
  3. Prepare for a future where AI agents become integral to workflows, but recognize the hidden infrastructure costs and security implications, particularly the growing importance of CPU capacity and robust access controls.
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February 4, 2026

⚡️ Context graphs: AI’s trillion-dollar opportunity — Jaya Gupta, Ashu Garg, Foundation Capital

Latent Space

AI
Key Takeaways:
  1. The shift from "how" to "why" in AI agent capabilities creates a new, multi-trillion-dollar market for companies that can capture institutional decision logic.
  2. Invest in or build agentic systems that are in the "right path" of business processes, actively capturing decision traces from unstructured data.
  3. Hundreds of context graphs will be in production at scale within a year, defining a new "context graph stack." The winning companies will be those that master this flywheel, extracting value to accelerate automation and build deep, defensible moats.
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February 2, 2026

We Entered an Era Where No One Knows What Comes Next

Turing Post

AI
Key Takeaways:
  1. The shift from linear, bottleneck-driven technological progress to a multi-layered, interconnected advancement model in AI has rendered traditional forecasting obsolete, forcing a re-evaluation of what "singularity" truly represents.
  2. Prioritize adaptability: Invest in modular, composable AI infrastructure and tools that thrive in multi-layered, unpredictable environments, rather than betting on single-bottleneck solutions.
  3. The inability to narrate AI's future means traditional roadmaps are obsolete; success hinges on navigating simultaneous, interconnected advancements and embracing the emergent.
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February 3, 2026

Why The Laws of Startup Physics Have Changed | Ben Horowitz Interview

Invest Like The Best

AI
Key Takeaways:
  1. The era of infrastructure-heavy tech deployment is over; AI's internet-native nature means immediate, widespread application. This shifts the competitive advantage from capital-intensive builds to rapid iteration and data leverage.
  2. Invest in companies that are not just using AI, but are fundamentally rethinking their business models around AI's ability to collapse traditional cost structures and accelerate product development.
  3. AI is a force multiplier for both individual opportunity and national power. Understanding its immediate deployability and the new rules of company building is crucial for investors and builders aiming to lead in the next wave of innovation over the next 12-24 months.
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February 2, 2026

Ben Horowitz and David Solomon: The Sweetest Macro Spot in 40 Years

a16z

AI
Key Takeaways:
  1. Unprecedented fiscal and monetary stimulus, coupled with a deregulatory environment, creates a powerful tailwind for financial assets and tech, driving a capital investment super cycle.
  2. Investors should prioritize companies with proprietary data and GPU access, as these are the new moats in an AI-driven world where traditional software leads are eroding.
  3. The convergence of a stimulative macro environment and AI's disruptive force means capital will flow to those who can scale, innovate, and navigate complex policy landscapes, making strategic positioning now critical for future relevance.
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Crypto Podcasts

January 31, 2026

LIVE: Gold vs. Bitcoin & MoltBook | 0xResearch

0xResearch

Crypto
Key Takeaways:
  1. The Macro Shift: Geopolitical tensions and economic uncertainty are driving a global re-allocation of capital, with Eastern wealth increasingly favoring hard assets and localized crypto rails. This challenges Western-centric market analysis and demands a broader, more nuanced view of global finance.
  2. The Tactical Edge: Cultivate deep domain expertise and critical thinking, using AI as an amplification tool, not a replacement for learning. Focus on areas where human judgment, taste, and the ability to translate AI insights into real-world value remain irreplaceable.
  3. The Bottom Line: The next 6-12 months will see continued divergence in global capital flows and accelerating AI integration. Investors must track opaque Eastern market signals, while builders should prioritize AI applications that augment human capability rather than simply automate, ensuring their skills remain relevant in an increasingly AI-driven world.
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January 30, 2026

The Fed Is Background Noise While Markets Reprice Reality | Weekly Roundup

Forward Guidance

Crypto
Key Takeaways:
  1. The Macro Shift: Monetary Escapism: As fiat debases and geopolitical tensions rise, capital is rotating from traditional tech to hard-capped assets and AI infrastructure.
  2. The Tactical Edge: Reallocate Capital: Prioritize real assets and cyclical commodities (gold, silver, oil, copper) while selectively shorting overvalued software companies facing AI disruption and increasing capital expenditures.
  3. The Bottom Line: The market is re-pricing value based on true scarcity and capital intensity. Position for a volatile environment where traditional narratives fail, and tangible assets or essential AI infrastructure dictate returns.
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January 29, 2026

The Most Underrated Chain: Celo’s Surprising Traction Around the World

Bankless

Crypto
Key Takeaways:
  1. The migration of the $3.2 quadrillion FX market to transparent, 24/7 blockchain rails.
  2. Build consumer-facing apps that utilize the phone-number-as-identity standard to capture the next 100 million users.
  3. Celo is the leading laboratory for real-world crypto adoption, proving that the Global Venmo dream is finally scaling.
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January 29, 2026

What If DOGE Actually Becomes Real Money?

The DCo Podcast

Crypto
Key Takeaways:
  1. The transition from speculative assets to utility-based currencies.
  2. Integrate low-fee payment rails like the Dogecoin GigaWallet to capture micro-transaction volume.
  3. Dogecoin is the dark horse of the next financial era because it prioritizes being used over being hoarded.
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January 28, 2026

LIVE: BITGO IPO, HIP-3, KNTQ | 0xResearch

0xResearch

Crypto
Key Takeaways:
  1. Capital no longer distinguishes between AI stocks and rare metals. Investors treat these as a single risk-on bucket settled on-chain.
  2. Monitor Hyperliquid deployers. Identify protocols moving from passive yield to active market-making to capture the next commodity rotation.
  3. The next year will favor platforms providing access to diverse asset classes. Pure crypto protocols must adapt or lose mindshare to trade everything venues.
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January 26, 2026

Metals Alt Season, Catchup Trades, Bitcoin vs Gold, Crypto Is Dead

1000x Podcast

Crypto
Key Takeaways:
  1. The Macro Transition: Hard Asset Migration. As fiat currencies lose purchasing power, capital moves into finite assets, starting with Gold and Bitcoin before trickling down to Silver and Ethereum.
  2. The Tactical Edge: Buy the Laggard. Identify assets with strong fundamentals that have underperformed the market leader by more than 30%.
  3. The Bottom Line: The catchup trade is the most profitable strategy when the primary leaders are consolidating.
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