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AI Podcasts

December 16, 2025

Finding The 1% of Stocks That Matter | Henry Ellenbogen Interview

Invest Like The Best

AI
Key Takeaways:
  1. Strategic Implication: The AI era will disproportionately reward existing businesses that deeply integrate AI to create unassailable cost structures, not just new AI-native ventures.
  2. Builder/Investor Note: Seek out resilient "Act II" leaders who embrace the "and" business—growth, innovation, and profitability—and are willing to navigate public market scrutiny for long-term alignment.
  3. The "So What?": Over the next 6-12 months, expect market volatility to create opportunities to invest in disciplined companies leveraging AI for fundamental operational shifts, rather than just hype.
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December 15, 2025

The Renaissance of the American Factory | a16z 2026 Big Ideas

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next wave of industrial growth will come from applying manufacturing principles to large-scale infrastructure, not just consumer goods.
  2. Builder/Investor Note: Focus on companies that are standardizing designs and processes for physical assets, particularly those leveraging AI to navigate regulatory complexity and accelerate deployment.
  3. The "So What?": The rapid build-out of data centers is a live experiment for a broader industrial renaissance, providing a blueprint for how America can rebuild its capacity to build at scale over the next 6-12 months.
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December 16, 2025

⚡️Jailbreaking AGI: Pliny the Liberator & John V on Red Teaming, BT6, and the Future of AI Security

Latent Space

AI
Key Takeaways:
  1. Strategic Implication: The "AI safety" narrative is shifting from content moderation to systemic security. Focus on hardening the entire AI ecosystem, not just restricting model outputs.
  2. Builder/Investor Note: Be wary of "AI security" products that claim to "secure the model" through guardrails. These are likely security theater. Invest in full-stack AI security solutions, red teaming services, and platforms that facilitate open-source adversarial research.
  3. The "So What?": The future of AI security is not about building higher walls around models, but about understanding and hardening the entire ecosystem in which they operate. Open collaboration and adversarial testing are the fastest paths to robust AI.
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December 15, 2025

Evolving Large Language Model Evaluation: Practices and Insights from the Swallow Project

Weights & Biases

AI
Key Takeaways:
  1. Strategic Implication: The quality and sophistication of LLM evaluation frameworks are now as critical as the models themselves. This is a foundational layer for AI progress.
  2. Builder/Investor Note: Builders must adopt adaptive evaluation. Investors should scrutinize how LLM performance is measured, not just the headline numbers.
  3. The "So What?": As LLMs gain complex reasoning and instruction-following abilities, evaluation frameworks that can accurately measure these capabilities will be essential for identifying true innovation and avoiding misallocated resources in the next 6-12 months.
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December 15, 2025

LLM Research and Development Initiatives at the National Institute of Informatics

Weights & Biases

AI
Key Takeaways:
  1. Sovereign AI is Real: Nations are investing in domestic AI capabilities to counter linguistic bias and ensure data control. This creates opportunities for specialized models and infrastructure.
  2. Builder's Edge: Meticulous parameter tuning, high-quality data curation, and innovative architectures like MoE are crucial for achieving top-tier LLM performance.
  3. The Agentic Future: AI agents are rapidly becoming indispensable tools in research and education, demanding robust, reliable, and culturally relevant LLM backbones.
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December 15, 2025

Coding Evals: From Code Snippets to Codebases – Naman Jain, Cursor

AI Engineer

AI
Key Takeaways:
  1. Strategic Implication: The future of AI code generation hinges on dynamic, robust evaluation systems that adapt to evolving model capabilities and detect sophisticated exploitation.
  2. Builder/Investor Note: Invest in or build evaluation infrastructure that incorporates dynamic problem sets, LLM-driven hack detection, and granular, human-centric metrics.
  3. The "So What?": Relying on static benchmarks is a losing game. The next 6-12 months will see a push towards more sophisticated, real-world-aligned evaluation methods, separating genuinely capable models from those that merely game the system.
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December 15, 2025

Building in the Gemini Era – Kat Kampf & Ammaar Reshi, Google DeepMind

AI Engineer

AI
Key Takeaways:
  1. Intent Over Implementation: The value in software creation shifts from low-level coding to clearly defining intent and design, with AI handling the technical execution.
  2. Rapid Prototyping: Builders can now rapidly prototype and deploy complex, full-stack applications, significantly compressing development cycles and lowering entry barriers.
  3. New Creator Economy: Expect a surge in non-technical creators building sophisticated applications, driving innovation in UI/UX and personalized content.
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December 15, 2025

The Renaissance of the American Factory | a16z 2026 Big Ideas

a16z

AI
Key Takeaways:
  1. Strategic Shift: The "factory-first" mindset is a strategic reorientation towards physical production, enabled by AI, extending beyond traditional manufacturing to all large-scale infrastructure.
  2. Builder/Investor Note: Focus on companies applying modular design, AI-driven process optimization, and automation to sectors like housing, energy, and mining. Data centers are a leading indicator for these trends.
  3. The "So What?": Rebuilding America's industrial capacity through these methods offers a competitive advantage, impacting defense, consumer goods, and commercial sectors in the next 6-12 months.
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December 13, 2025

Minimax M2 – Olive Song, MiniMax

AI Engineer

AI
Key Takeaways:
  1. Strategic Implication: The future of AI agents hinges on practical utility and adaptive reasoning, not just raw scale. Models that integrate expert feedback and iterative thinking will outperform those focused solely on benchmarks.
  2. Builder/Investor Note: Builders should prioritize robust generalization through diverse training perturbations. Investors should seek models that demonstrate real-world adoption and cost-effective scalability for multi-agent architectures.
  3. The So What?: The next 6-12 months will see a shift towards smaller, highly specialized, and deeply integrated AI models that function as reliable co-workers, driving efficiency in developer workflows and complex agentic tasks.
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Crypto Podcasts

June 2, 2025

Finding Product Market Fit In Crypto

Lightspeed

Crypto
Key Takeaways:
  1. **Infrastructure is the New Frontier:** Prioritize crypto ventures using blockchain as a foundational layer to innovate and compete with Web2, moving beyond purely crypto-centric applications.
  2. **Solve Real Problems, Not Chase Hypotheses:** True PMF stems from addressing tangible user pain points; market creation is often a byproduct of successful problem-solving, not an initial goal.
  3. **Large Markets Fuel Pivots:** While a sharp focus is vital, building within a substantial market provides the necessary runway and adjacent opportunities critical for navigating the path to PMF.
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June 2, 2025

The Race to Replace Mainnet | Ian Unsworth, Kairos Research

0xResearch

Crypto
Key Takeaways:
  1. UX is King: Seamless, integrated user experiences (like Hyperliquid's or a desired "Robin Hood for crypto") will win, as fragmentation (EVM L2s) breeds user frustration and churn.
  2. Solana's Ascent: Alpenlow’s 150ms finality and zero voting costs significantly enhance Solana's competitive edge, driven by an "underdog" culture of relentless improvement.
  3. ETH's Identity Search: Ethereum needs decisive leadership and a unified technical/narrative strategy to counter fragmentation and challengers; price pressure often serves as its main catalyst for action.
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June 1, 2025

We Asked Flood About His Hyperliquid Bull Thesis

The Rollup

Crypto
Key Takeaways:
  1. **Hyperliquid (Hype) is King:** Flood states, "It's the only asset that matters in crypto other than Bitcoin... Nothing else makes money," citing its strong fundamentals and mispricing.
  2. **L1s are Uninvestable Commodities:** Focus on applications and frontends that directly serve users; L1s are a race to the bottom on fees and vulnerable to tech disruption.
  3. **Builder Codes Fuel an Ecosystem:** Hyperliquid's permissionless monetization will attract a wave of development, creating a moat through network effects and specialized user experiences.
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May 31, 2025

LIVE Hivemind: Crypto Treasury Companies, Sui Hack & Solana’s New Consensus

Empire

Crypto
Key Takeaways:
  1. Treasury Tactics: The "treasury company" model is the new "low float, high FDV" game, but relies on continued premium valuations and favorable debt markets; watch out for stress when debt matures.
  2. Sui's Pragmatism: Sui’s handling of the Cetus hack signals that newer chains may prioritize decisive action and recovery over decentralization purity in crises, a trend likely to continue.
  3. Solana's Evolution: Solana’s major consensus upgrade, developed by former critics, showcases a pragmatic, engineering-first approach focused on performance and validator accessibility, potentially strengthening its L1 position.
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May 31, 2025

Where Crypto Meets AI with Chris Dixon & David George

a16z

Crypto
Key Takeaways:
  1. Crypto Delivers Utility: Stablecoins move trillions monthly, proving crypto's real-world value beyond speculation for fast, cheap global payments.
  2. AI Rewrites Web Economics: AI's direct-answer capability breaks the old ad-traffic model. Crypto offers tools to build the new economic "covenant" required.
  3. Bet on Category Kings: Tech markets are "winner-take-all." Focus on the dominant player in any credible category, especially those led by founders with unique, "earned secrets."
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May 30, 2025

The Solana Incubator: Finding Crypto's Next Breakthrough App | Emon Motamedi

Lightspeed

Crypto
Key Takeaways:
  1. Build Real, Not Just Rallies: Prioritize long-term, sustainable businesses with tangible revenue models over chasing fleeting crypto trends.
  2. Utility Tokens Trump Speculation: Design tokens to solve core project problems or incentivize user behavior, not merely for market hype.
  3. Solana's Next Wave: Infrastructure for Reality: Leverage crypto as a backend for innovative solutions to real-world problems, targeting broader, non-crypto native audiences.
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