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AI Podcasts

November 17, 2025

Hash Rate - Ep 145 - TAO Subnets Templar (3), Basilica (39), Grail (81)

Hash Rate pod - Bittensor $TAO & Subnets

AI
Key Takeaways:
  1. **A New Market is Born:** Templar isn't just cheaper; it enables something that was previously impossible for 99% of the world. Democratizing pre-training means anyone can build a truly custom, sovereign AI.
  2. **Productization is Underway:** Covenant is no longer just a research project. With enterprise sales in motion, the focus is now on revenue. The team has committed that 100% of fees from custom training will be used to buy back its tokens.
  3. **Economics are Being Rewritten:** Basilica’s incentive mechanism is a direct critique of unsustainable models on other compute subnets. Its focus on profitability and positive TAO flow sets a new standard for economic design on Bittensor.
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November 17, 2025

Bryan Johnson: Don’t Die, Beating Entropy, AI Alignment & The Two-Species Future

Bankless

AI
Key Takeaways:
  1. AI Forces a Moral Reboot. The emergence of superintelligence renders our current societal goals dangerously obsolete. Survival must become the new prime directive.
  2. Existence is a Team Sport. The "Don't Die" philosophy is a collective mission ("we don't die") to ensure species-wide survival, not a selfish quest for individual immortality.
  3. Prepare for the Biological Sandbox. Humanity is moving from manipulating physical atoms and digital bits to programming our own biology—a frontier with both unimaginable potential and catastrophic risk.
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November 17, 2025

Emmett Shear on Building AI That Actually Cares: Beyond Control and Steering

a16z

AI
Key Takeaways:
  1. Stop Trying to “Steer” AGI. The control paradigm is a dead end. The goal isn’t a more obedient tool; it’s a trustworthy teammate. We must shift from engineering control to cultivating care.
  2. Alignment is a Process, Not a Product. True alignment isn't a fixed set of rules. It’s a dynamic process of moral learning, akin to raising a child. AIs that only follow rules are brittle and dangerous.
  3. Build for Cooperation, Not Command. The technical path forward involves training AIs in rich, multi-agent environments where they must learn cooperation and theory of mind—the foundational skills for becoming a good member of a group.
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November 16, 2025

Rawson Haverty presents "US & China AI: Lessons from Across the Pacific" | dAGI Summit 2025

Delphi Digital

AI
Key Takeaways:
  1. US Leads in Capital-Intensive Frontier AI; China Excels at Industrial Diffusion. The US leverages deep capital markets for its massive compute buildout and AGI research, while China uses state direction to embed AI into its vast industrial base via open-source models and hardware.
  2. Market Structure Dictates AI Strategy. The US "efficient oligopoly" model prioritizes global dominance and profit reinvestment by a few players. China's "subjugated swarm" model creates intense domestic competition, driving down prices and accelerating adoption at the cost of profitability.
  3. Geopolitical Tension May Be a Necessary Stabilizer. The competition between the US's freedom-oriented, frontier-pushing approach and China's stability-focused, diffusion-driven model creates a complementary tension that could be essential for navigating the "narrow corridor" between AI-driven totalitarianism and uncontrollable chaos.
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November 13, 2025

How Will AI Change Gaming Development? (A Dev’s Take)

The DCo Podcast

AI
Key Takeaways:
  1. Development timelines are collapsing from months to days. AI allows developers to swap entire asset libraries or generate new game concepts at unprecedented speed, turning a two-month art project into a day's work.
  2. The lifespan of any single game is shrinking. Prepare for a world of disposable entertainment. As AI floods the market with content, the strategy will pivot from creating one long-lasting hit to deploying a rapid succession of engaging experiences.
  3. Games are the next evolution of the attention economy. Just as memes became a core tool for community-building around tokens, easily created games will be the next engine for capturing and directing user attention in a hyper-competitive digital world.
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November 11, 2025

AI Nerves, Crypto Realism, Privacy Coins, & Lessons From Trading

1000x Podcast

AI
Key Takeaways:
  1. Adopt a Stock Picker's Mentality. The crypto market is no longer a monolith where a rising tide lifts all boats. Focus on assets with real products, user growth, and cash flow, as the gap between winners and losers will only widen.
  2. Shorting is a Tactical Assault, Not a Siege. Don't "invest" in a short. The only viable short strategies are tactical, targeting specific events like VC unlocks or news-driven spikes. Otherwise, even "total scams" can 5x against you.
  3. Cultivate a Goldfish's Memory. The most critical trading skill is learning how to change your mind. Cut losing trades, forget the loss (but remember the lesson), and redeploy capital without emotional baggage. Stubbornness is a portfolio killer.
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November 11, 2025

Grant Lee: Building Gamma’s AI Presentation Company to 100 Million Users

a16z

AI
Key Takeaways:
  1. Word-of-mouth isn't a feature; it's the engine. Before spending a dime on marketing, obsess over the first 30 seconds of the user experience until people can't help but share it.
  2. Being different is better than being better. Don't build incrementally better slideware. Redefine the core primitives of your category, as Gamma did by moving beyond the 16x9 slide.
  3. Hire painfully slowly to protect your DNA. Resisting the temptation to scale headcount with user growth is a superpower. The goal isn't to hit a hiring target; it's to hire the best people.
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November 7, 2025

Amjad Masad & Adam D’Angelo: How Far Are We From AGI?

a16z

AI
Key Takeaways:
  1. AGI Is a Definitional Debate. Progress toward an AI that can replace a remote worker is happening fast. However, achieving "true" human-like learning efficiency may require an entirely new paradigm beyond scaling current LLMs.
  2. The New Creator Economy Is Code. AI is turning software development into a mainstream creative pursuit, empowering a new class of solo entrepreneurs who can build what previously required entire teams.
  3. Incumbents Learned Their Lesson. Unlike past tech shifts, today's giants are aggressively adopting AI, making it both a sustaining *and* disruptive force. The market is large enough for both incumbents and startups to create massive value.
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November 6, 2025

Mark Zuckerberg & Priscilla Chan: How AI Will Cure All Disease

a16z

AI
Key Takeaways:
  1. Build the Tools, Not Just the House: CZI’s greatest leverage comes from creating open-source tools and datasets. By building the fundamental infrastructure, they empower the entire scientific community—from academic labs to startups—to accelerate discovery.
  2. Data Is the New Microscope: The future of biology hinges on a tight feedback loop between generating novel, purpose-built datasets and training domain-specific AI models on them. This synergy is unlocking insights that were previously impossible.
  3. Virtual Biology Is the Next Frontier: Simulating biology computationally with "virtual cells" will become the new standard for research, enabling scientists to test riskier hypotheses faster and cheaper, dramatically compressing the timeline for major breakthroughs.
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Crypto Podcasts

February 12, 2026

Novelty Search feb 12, 2026

taostats

Crypto
Key Takeaways:
  1. The push for radical decentralization, as seen with Dynamic TAO's token transformation, inherently introduces market inefficiencies and bad actors, compelling communities to develop emergent, permissionless self-regulation mechanisms to achieve economic viability.
  2. Design for resilience, not prevention; assume bad actors will exist in any truly permissionless system and build in mechanisms for community-led critique and adaptation.
  3. The next 6-12 months will reward projects that embrace the full spectrum of permissionless market dynamics, understanding that robust, self-correcting communities are more valuable than perfectly sanitized, centrally controlled ones.
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February 12, 2026

What’s the Story? AI Stocks, Crypto Downturn, Metals Selloff, SaaSpocalypse | Jim Bianco

Bankless

Crypto
Key Takeaways:
  1. AI's cost-compression power is fundamentally altering software economics, shifting value from infrastructure providers to application builders and traditional businesses, while exposing the inherent instability of leveraged "synthetic" markets in crypto.
  2. Re-evaluate portfolio allocations, considering a rotation towards traditional companies benefiting from AI's cost efficiencies and a long-term view on crypto projects focused on building replacement financial systems.
  3. The current market volatility is a re-pricing of assets in an AI-first world. Understanding where value truly accrues and crypto's need for a new, disruptive narrative will be critical for navigating the next 6-12 months.
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February 12, 2026

Building the Next-Gen Perps Engine on Solana | Tristan Frizza

Lightspeed

Crypto
Key Takeaways:
  1. FTX's collapse highlighted the need for transparent, self-custodial exchanges. Bullet's design ensures all operations are auditable on-chain, giving users full control of their funds.
  2. Market makers on Solana L1 faced adverse selection, where bots with faster connections could front-run their price updates. This led to consistent losses for liquidity providers.
  3. Increased market maker confidence leads to deeper order books and tighter spreads. This directly benefits all traders with better pricing and less slippage.
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February 12, 2026

BlackRock Buys UNI, Tokenized iShares, Robinhood L2 Testnet Live, & Santiago Santos & RJ

The Rollup

Crypto
Key Takeaways:
  1. The Macro Shift: TradFi's embrace of crypto rails, stablecoins, and tokenized assets is undeniable, driving a new era of "Neo Finance" where efficiency gains are captured by businesses, not always the underlying protocols' tokens.
  2. The Tactical Edge: Prioritize projects with clear revenue models and token designs that actively reinvest or distribute value to holders, mimicking equity-like compounding. Look for teams with agile decision-making.
  3. The Bottom Line: The next 6-12 months will see a continued repricing of crypto assets. Focus on applications and "crypto-enabled equity" that demonstrate real cash flow and a path to compounding value, rather than speculative infrastructure plays.
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February 11, 2026

Gordon Frayne: Tao Ecosystem Insights, Bittensor Subnets vs ERC20 Tokens DeFi Liquidity | Ep. 81

Ventura Labs

Crypto
Key Takeaways:
  1. Decentralized AI evolves beyond simple compute, with Bittensor establishing a "proof of useful work" model. This incentivizes specialized intelligence and democratizes early-stage AI investment.
  2. Research and allocate capital to Bittensor subnets with strong fundamentals and high staking yields (30-150% APY), outperforming TAO.
  3. Bittensor's unique tokenomics and incentive layer position it as critical infrastructure for decentralized AI. This offers investors and builders a compelling opportunity to accrue value in a high-growth ecosystem.
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February 11, 2026

Would BlackRock Try to Save Bitcoin From the Quantum Threat? - Bits + Bips

Unchained

Crypto
Key Takeaways:
  1. Institutional capital is forcing a re-evaluation of crypto's core tenets, pushing for greater accountability and risk mitigation, particularly in Bitcoin's governance.
  2. Prioritize investments in crypto projects demonstrating clear cash flows, real-world utility, and robust, responsive governance, rather than speculative tokens.
  3. Bitcoin's future hinges on its ability to adapt to external pressures, especially the quantum threat. Investors should monitor how institutions influence this change, as the "boring", cash-generating parts of crypto and AI infrastructure are poised for growth.
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