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AI Podcasts

February 3, 2026

Why The Laws of Startup Physics Have Changed | Ben Horowitz Interview

Invest Like The Best

AI
Key Takeaways:
  1. The Macro Shift: AI is collapsing the time horizon for technological deployment and market dominance, shifting the competitive advantage from pure innovation to a combination of innovation, capital, and rapid infrastructure deployment.
  2. The Tactical Edge: Invest in companies that are not just building AI, but are fundamentally rethinking existing industries with AI-first principles, recognizing that traditional software moats are eroding.
  3. The Bottom Line: The next 12-24 months will see AI's broad impact kick in, creating unprecedented opportunities for those who understand its new "laws of physics" and the critical role of policy in shaping its trajectory.
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February 4, 2026

Ozempic Won't Solve America's Obesity Problem

a16z

AI
Key Takeaways:
  1. The healthcare system is moving from reactive, acute care to proactive, preventative interventions, driven by the unsustainable costs of chronic disease and a growing understanding of environmental health.
  2. Build infrastructure that financially incentivizes lifestyle interventions, such as TrueMed's HSA/FSA payment rails for health-promoting products and services.
  3. The next decade will see hundreds of billions of dollars redirected towards preventative health. Companies that bridge the gap between lifestyle choices and healthcare financing will capture significant market share.
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February 3, 2026

SpaceX Engineer Explains America's Biggest Energy Mistake | Scott Nolan, CEO of General Matter

The Generalist

AI
Key Takeaways:
  1. The Macro Shift: Global energy demand, driven by AI, forces a strategic re-evaluation of nuclear power. This creates a window for nations to re-shore critical energy infrastructure, moving from reliance on adversaries to domestic, cost-competitive solutions.
  2. The Tactical Edge: Investigate companies addressing foundational supply chain gaps in critical industries like energy. Look for teams with a "first principles" engineering approach and a track record of commercializing hard tech.
  3. The Bottom Line: America's energy independence and its ability to power future technological growth, like AI, hinge on rebuilding domestic nuclear fuel enrichment. This is not just an industrial opportunity; it is a national security imperative.
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February 4, 2026

The Economic Singularity Will Make Today’s Economy Unrecognizable w/ Dr. Alexander Wissner-Gross

Milk Road AI

AI
Key Takeaways:
  1. The Macro Shift: AI-driven hyperdeflation is colliding with the technical reality of autonomous AI agents creating their own crypto-backed economies, threatening a decoupling from human fiat systems.
  2. The Tactical Edge: Investigate and build infrastructure that bridges human and AI economies, focusing on fiat-to-crypto rails that can accommodate agent-driven transactions to prevent a complete split.
  3. The Bottom Line: The next 5-10 years will see an unprecedented economic transformation. Understanding AI's deflationary power and the emerging AI agent economy is critical for navigating a world where traditional economic models may no longer apply.
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February 3, 2026

OpenClaw Makes AI Agents and CPUs Get Real

Semi Doped

AI
Key Takeaways:
  1. The time of practical AI agents is here, moving compute demand beyond pure GPU inference to a significant reliance on CPUs for coordination, data handling, and security.
  2. Evaluate your agent deployment strategy now, prioritizing sandboxed environments (VPS, dedicated local servers) and exploring cost-optimized model routing to manage API expenses.
  3. Prepare for a future where AI agents become integral to workflows, but recognize the hidden infrastructure costs and security implications, particularly the growing importance of CPU capacity and robust access controls.
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February 4, 2026

⚡️ Context graphs: AI’s trillion-dollar opportunity — Jaya Gupta, Ashu Garg, Foundation Capital

Latent Space

AI
Key Takeaways:
  1. The shift from "how" to "why" in AI agent capabilities creates a new, multi-trillion-dollar market for companies that can capture institutional decision logic.
  2. Invest in or build agentic systems that are in the "right path" of business processes, actively capturing decision traces from unstructured data.
  3. Hundreds of context graphs will be in production at scale within a year, defining a new "context graph stack." The winning companies will be those that master this flywheel, extracting value to accelerate automation and build deep, defensible moats.
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February 2, 2026

We Entered an Era Where No One Knows What Comes Next

Turing Post

AI
Key Takeaways:
  1. The shift from linear, bottleneck-driven technological progress to a multi-layered, interconnected advancement model in AI has rendered traditional forecasting obsolete, forcing a re-evaluation of what "singularity" truly represents.
  2. Prioritize adaptability: Invest in modular, composable AI infrastructure and tools that thrive in multi-layered, unpredictable environments, rather than betting on single-bottleneck solutions.
  3. The inability to narrate AI's future means traditional roadmaps are obsolete; success hinges on navigating simultaneous, interconnected advancements and embracing the emergent.
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February 3, 2026

Why The Laws of Startup Physics Have Changed | Ben Horowitz Interview

Invest Like The Best

AI
Key Takeaways:
  1. The era of infrastructure-heavy tech deployment is over; AI's internet-native nature means immediate, widespread application. This shifts the competitive advantage from capital-intensive builds to rapid iteration and data leverage.
  2. Invest in companies that are not just using AI, but are fundamentally rethinking their business models around AI's ability to collapse traditional cost structures and accelerate product development.
  3. AI is a force multiplier for both individual opportunity and national power. Understanding its immediate deployability and the new rules of company building is crucial for investors and builders aiming to lead in the next wave of innovation over the next 12-24 months.
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February 2, 2026

Ben Horowitz and David Solomon: The Sweetest Macro Spot in 40 Years

a16z

AI
Key Takeaways:
  1. Unprecedented fiscal and monetary stimulus, coupled with a deregulatory environment, creates a powerful tailwind for financial assets and tech, driving a capital investment super cycle.
  2. Investors should prioritize companies with proprietary data and GPU access, as these are the new moats in an AI-driven world where traditional software leads are eroding.
  3. The convergence of a stimulative macro environment and AI's disruptive force means capital will flow to those who can scale, innovate, and navigate complex policy landscapes, making strategic positioning now critical for future relevance.
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Crypto Podcasts

February 2, 2026

The Last Companies That Will Ever Exist

Bankless

Crypto
Key Takeaways:
  1. The global economy is transitioning from a "bits" era of digital innovation to an "atoms" era, driven by AI and robotics, where control over physical resources and their efficient deployment becomes the ultimate competitive advantage.
  2. Prioritize investments in companies demonstrating vertical integration across intelligence, energy, and labor, especially those building physical infrastructure and manufacturing capabilities at scale.
  3. The race to acquire the "Infinity Gauntlet" of capitalism is on. Companies that achieve self-sufficiency in intelligence, energy, and labor will redefine economic power, making traditional capital almost irrelevant and creating a new class of unassailable monopolies.
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February 2, 2026

Logan Jastremski: Solana vs Hyperliquid - Who Wins The Global Exchange Race?

Delphi Digital

Crypto
Key Takeaways:
  1. The global financial system demands 24/7, credibly neutral price discovery. This pushes blockchain architecture beyond raw throughput to geographically optimized, low-latency transaction inclusion, creating a truly global market.
  2. Invest in infrastructure and applications on chains pursuing multi-leader consensus and proprietary AMMs. These designs offer superior price discovery and execution for the next generation of global trading.
  3. The global exchange race is an engineering marathon, not a sprint. While Hyperliquid excels regionally, Solana's architectural bet on physics-defying global fairness aims to become the world's true price oracle, unlocking trillions in new trading volume.
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February 2, 2026

How to Fix Tokenized Securities with Olivia Olivia Vande Woude from Ava Labs

The Rollup

Crypto
Key Takeaways:
  1. Trust is moving from opaque balance sheets to verifiable, cryptographically enforced infrastructure. This means financial protocols, not just institutions, will increasingly dictate settlement, custody, and compliance.
  2. Prioritize tokenized assets and investment vehicles that offer direct legal claims and verifiable on-chain mechanics. For builders, focus on creating infrastructure that eliminates intermediaries and provides transparent, programmable utility, like vaults.
  3. The future of finance is about verifiable infrastructure and programmable ownership. Understanding the nuances of tokenized security structures and the rise of on-chain vaults will be critical for investors and builders navigating the convergence of traditional finance and DeFi over the next 6-12 months.
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February 2, 2026

The 1010 Exploit and other broken market structures

The Gwart Show

Crypto
Key Takeaways:
  1. The market is demanding verifiable, transparent, and capital-efficient trading venues that eliminate the hidden risks of centralized intermediaries. This pushes innovation towards fully onchain, unified risk engines.
  2. Explore platforms that integrate multiple DeFi primitives (spot, perp, lending) under a single, onchain risk engine. These venues offer superior capital efficiency and potentially higher risk-adjusted returns for sophisticated strategies like basis trades.
  3. The next wave of DeFi success will come from platforms that solve for capital productivity and verifiable safety, attracting institutional and sophisticated retail capital by offering returns previously unattainable in fragmented or opaque markets.
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February 1, 2026

Crypto is so Cooked.

Taiki Maeda

Crypto
Key Takeaways:
  1. The Macro Shift: Institutional capital flow dictates market cycles; the current downturn purges weak projects, paving the way for a value-driven recovery.
  2. The Tactical Edge: Identify projects with genuine value accrual, strong fundamentals, and potential for buybacks, preparing to dollar-cost average into these "Carvana" plays.
  3. The Bottom Line: The current "gross" feeling is a signal to strategically deploy capital into long-term, high-conviction assets, rather than short-term trading.
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February 1, 2026

Looking for Gains Right Now? Crypto Isn’t the Trade — This Is: Bits + Bips

Unchained

Crypto
Key Takeaways:
  1. Capital is migrating from speculative, long-tail crypto assets to tokenized real-world assets and sophisticated derivatives. This reflects a broader market demand for yield, hedging, and perceived stability.
  2. Explore tokenized commodities (gold, silver) and equity perpetuals for new leverage and yield opportunities. Exercise extreme caution with prediction markets and weekend tokenized equity trading due to information asymmetry and manipulation risks.
  3. The crypto market is maturing beyond pure digital assets, integrating with traditional finance through tokenization and derivatives. Position your portfolio to capture value from this convergence, prioritizing robust liquidity and verifiable information over pure speculation.
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