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AI Podcasts

February 3, 2026

Why The Laws of Startup Physics Have Changed | Ben Horowitz Interview

Invest Like The Best

AI
Key Takeaways:
  1. The Macro Shift: AI is collapsing the time horizon for technological deployment and market dominance, shifting the competitive advantage from pure innovation to a combination of innovation, capital, and rapid infrastructure deployment.
  2. The Tactical Edge: Invest in companies that are not just building AI, but are fundamentally rethinking existing industries with AI-first principles, recognizing that traditional software moats are eroding.
  3. The Bottom Line: The next 12-24 months will see AI's broad impact kick in, creating unprecedented opportunities for those who understand its new "laws of physics" and the critical role of policy in shaping its trajectory.
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February 4, 2026

Ozempic Won't Solve America's Obesity Problem

a16z

AI
Key Takeaways:
  1. The healthcare system is moving from reactive, acute care to proactive, preventative interventions, driven by the unsustainable costs of chronic disease and a growing understanding of environmental health.
  2. Build infrastructure that financially incentivizes lifestyle interventions, such as TrueMed's HSA/FSA payment rails for health-promoting products and services.
  3. The next decade will see hundreds of billions of dollars redirected towards preventative health. Companies that bridge the gap between lifestyle choices and healthcare financing will capture significant market share.
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February 3, 2026

SpaceX Engineer Explains America's Biggest Energy Mistake | Scott Nolan, CEO of General Matter

The Generalist

AI
Key Takeaways:
  1. The Macro Shift: Global energy demand, driven by AI, forces a strategic re-evaluation of nuclear power. This creates a window for nations to re-shore critical energy infrastructure, moving from reliance on adversaries to domestic, cost-competitive solutions.
  2. The Tactical Edge: Investigate companies addressing foundational supply chain gaps in critical industries like energy. Look for teams with a "first principles" engineering approach and a track record of commercializing hard tech.
  3. The Bottom Line: America's energy independence and its ability to power future technological growth, like AI, hinge on rebuilding domestic nuclear fuel enrichment. This is not just an industrial opportunity; it is a national security imperative.
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February 4, 2026

The Economic Singularity Will Make Today’s Economy Unrecognizable w/ Dr. Alexander Wissner-Gross

Milk Road AI

AI
Key Takeaways:
  1. The Macro Shift: AI-driven hyperdeflation is colliding with the technical reality of autonomous AI agents creating their own crypto-backed economies, threatening a decoupling from human fiat systems.
  2. The Tactical Edge: Investigate and build infrastructure that bridges human and AI economies, focusing on fiat-to-crypto rails that can accommodate agent-driven transactions to prevent a complete split.
  3. The Bottom Line: The next 5-10 years will see an unprecedented economic transformation. Understanding AI's deflationary power and the emerging AI agent economy is critical for navigating a world where traditional economic models may no longer apply.
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February 3, 2026

OpenClaw Makes AI Agents and CPUs Get Real

Semi Doped

AI
Key Takeaways:
  1. The time of practical AI agents is here, moving compute demand beyond pure GPU inference to a significant reliance on CPUs for coordination, data handling, and security.
  2. Evaluate your agent deployment strategy now, prioritizing sandboxed environments (VPS, dedicated local servers) and exploring cost-optimized model routing to manage API expenses.
  3. Prepare for a future where AI agents become integral to workflows, but recognize the hidden infrastructure costs and security implications, particularly the growing importance of CPU capacity and robust access controls.
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February 4, 2026

⚡️ Context graphs: AI’s trillion-dollar opportunity — Jaya Gupta, Ashu Garg, Foundation Capital

Latent Space

AI
Key Takeaways:
  1. The shift from "how" to "why" in AI agent capabilities creates a new, multi-trillion-dollar market for companies that can capture institutional decision logic.
  2. Invest in or build agentic systems that are in the "right path" of business processes, actively capturing decision traces from unstructured data.
  3. Hundreds of context graphs will be in production at scale within a year, defining a new "context graph stack." The winning companies will be those that master this flywheel, extracting value to accelerate automation and build deep, defensible moats.
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February 2, 2026

We Entered an Era Where No One Knows What Comes Next

Turing Post

AI
Key Takeaways:
  1. The shift from linear, bottleneck-driven technological progress to a multi-layered, interconnected advancement model in AI has rendered traditional forecasting obsolete, forcing a re-evaluation of what "singularity" truly represents.
  2. Prioritize adaptability: Invest in modular, composable AI infrastructure and tools that thrive in multi-layered, unpredictable environments, rather than betting on single-bottleneck solutions.
  3. The inability to narrate AI's future means traditional roadmaps are obsolete; success hinges on navigating simultaneous, interconnected advancements and embracing the emergent.
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February 3, 2026

Why The Laws of Startup Physics Have Changed | Ben Horowitz Interview

Invest Like The Best

AI
Key Takeaways:
  1. The era of infrastructure-heavy tech deployment is over; AI's internet-native nature means immediate, widespread application. This shifts the competitive advantage from capital-intensive builds to rapid iteration and data leverage.
  2. Invest in companies that are not just using AI, but are fundamentally rethinking their business models around AI's ability to collapse traditional cost structures and accelerate product development.
  3. AI is a force multiplier for both individual opportunity and national power. Understanding its immediate deployability and the new rules of company building is crucial for investors and builders aiming to lead in the next wave of innovation over the next 12-24 months.
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February 2, 2026

Ben Horowitz and David Solomon: The Sweetest Macro Spot in 40 Years

a16z

AI
Key Takeaways:
  1. Unprecedented fiscal and monetary stimulus, coupled with a deregulatory environment, creates a powerful tailwind for financial assets and tech, driving a capital investment super cycle.
  2. Investors should prioritize companies with proprietary data and GPU access, as these are the new moats in an AI-driven world where traditional software leads are eroding.
  3. The convergence of a stimulative macro environment and AI's disruptive force means capital will flow to those who can scale, innovate, and navigate complex policy landscapes, making strategic positioning now critical for future relevance.
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Crypto Podcasts

July 30, 2025

How The U.S. Controls The Global Economy

Bankless

Crypto
Key Takeaways:
  1. Crypto Is America's Counter-Offensive. The U.S. is betting on privately-issued, regulated stablecoins—not a government-backed digital dollar—to maintain its edge in global payments. This strategy mirrors how it co-opted the offshore Eurodollar market in the 1970s to expand the dollar’s influence.
  2. The Rise of Parallel Systems. The weaponization of the dollar is forcing countries like China to build their own financial infrastructure (e.g., the M-Bridge platform). This guarantees a future where nations have multiple payment networks to choose from, eroding the U.S.’s unique leverage.
  3. Sanctions Are Not a Free Lunch. While a powerful alternative to military conflict, economic sanctions must be used judiciously. Overusing them risks dulling their impact and ultimately dismantling the very system that grants the U.S. its power.
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July 30, 2025

Can ETH Outperform SOL In 2025?

Lightspeed

Crypto
Key Takeaways:
  1. ETH's Narrative Is Its Near-Term Weapon. ETH's strength lies in a story simple enough for a "dumb banker": massive market cap, 80%+ stablecoin dominance, and the perceived success of its L2s. This makes it an easier buy for TradFi, even if the value accrual thesis is murky.
  2. Solana Is Playing The Long Game. Solana is betting that superior tech will ultimately win. Its focus isn't on the current TradFi narrative but on building the infrastructure for future "internet capital markets," a strategy that requires patience.
  3. Stablecoin Liquidity Is a Vanity Metric. Billions in stablecoins on platforms like Aave don't automatically translate to productive economic activity. The primary use case remains on-chain speculation, challenging the idea that massive liquidity is an end in itself.
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July 29, 2025

ETH Makes a Comeback While Crypto’s Animal Spirits Revive - Bits + Bips

Unchained

Crypto
Key Takeaways:
  1. Ditch the Beta, Pick Your Alts: The days of everything moving in unison are fading. Idiosyncratic returns are back, rewarding investors who can identify projects with strong, sustainable tokenomics.
  2. Beware the Treasury Treadmill: The crypto treasury model is not an "infinite money glitch." Expect premiums to compress and consolidation to begin as the market becomes saturated and the ability to raise capital at a premium wanes.
  3. Tokenization is the Next Frontier: The real institutional play is the rise of "internet capital markets." The tokenization of money market funds by giants like BNY and Goldman will create new, regulated avenues for investment and yield generation on-chain.
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July 29, 2025

Has ETH/BTC Bottomed?

1000x Podcast

Crypto
Key Takeaways:
  1. Price Action Is the Best Marketing. ETH’s bullish chart has single-handedly revived interest, breaking a long-term downtrend against BTC and forcing even skeptics to reconsider. The technicals are now undeniably strong.
  2. ETH Is Wall Street’s High-Beta Darling. New institutional money, looking for 5-10x returns and limited to what’s available in brokerage accounts, is flowing into ETH as the logical next step down the risk curve from Bitcoin.
  3. Trade Your Conviction. Don't chase a rally you don't understand. Entering a trade based on technicals without a fundamental framework is a recipe for selling the lows when volatility hits. For some, leveraged Bitcoin remains a more coherent trade.
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July 29, 2025

Why Charles Hoskinson Is Still Actively Involved In Crypto

Empire

Crypto
Key Takeaways:
  1. Crypto as a Political Countermeasure: For Hoskinson, blockchain is the practical tool to enforce the sound money and transparent governance that the US government has abandoned.
  2. The Federal Reserve Is a Core Target: He identifies the Federal Reserve's unchecked power over the monetary supply as a central flaw in the current system, positioning decentralized currencies as a direct challenge to its authority.
  3. A Mission, Not a Job: His daily engagement isn't for financial gain but is driven by the conviction that the fight for a more honest and accountable system is far from over.
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July 29, 2025

The State Of Solana With Carlos Gonzalez Campo

Lightspeed

Crypto
Key Takeaways:
  1. Tech Over Hype: Solana’s long-term bet is on fundamental technology. Upgrades like Jito’s BAM are designed to create a superior on-chain environment for sophisticated finance, even if it means losing short-term narrative battles to ETH.
  2. The Institutional Gap: Ethereum is currently winning the institutional game with simple, powerful stories around stablecoins and treasury assets. Solana needs a clearer, more accessible pitch beyond raw performance to compete for this capital.
  3. Performance is Non-Negotiable: The Solana ecosystem is doubling down on its high-throughput thesis. Expect a continued push for more blockspace and faster finality, even if it makes running a validator more exclusive. The trade-off is deemed worth it to bring global-scale finance on-chain.
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