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AI Podcasts

December 17, 2025

Rethinking Pre-Training for Agentic AI [Aakanksha Chowdhery] - 759

The TWIML AI Podcast with Sam Charrington

AI
Key Takeaways:
  1. Pre-Training is the New Frontier: The next leap in AI capabilities, particularly for agentic systems, will come from fundamental advancements in pre-training, not just post-training tweaks.
  2. Builders & Investors: Focus on teams rethinking loss objectives, curating high-quality reasoning data, and developing dynamic benchmarks for agentic capabilities. Be wary of "agentic" claims that lack foundational pre-training innovation.
  3. The "So What?": Over the next 6-12 months, expect a push for new benchmarks and data strategies that explicitly train models for multi-step planning, long-form reasoning, and error recovery, moving beyond simple next-token prediction.
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December 16, 2025

What We Learned Deploying AI within Bloomberg’s Engineering Organization – Lei Zhang, Bloomberg

AI Engineer

AI
Key Takeaways:
  1. Strategic Implication: AI fundamentally changes the economics of software development. Organizations must re-evaluate what constitutes "high-quality" engineering and adapt their processes.
  2. Builder/Investor Note: Prioritize platforms that provide guardrails and guidance for AI tool usage, focusing on deterministic verification and robust testing. Uncontrolled AI deployment risks technical debt.
  3. The "So What?": The next 6-12 months will see a bifurcation: companies that strategically integrate AI into their engineering culture and platforms will gain significant efficiency, while those that don't will struggle with quality and adoption.
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December 16, 2025

Your Support Team Should Ship Code – Lisa Orr, Zapier

AI Engineer

AI
Key Takeaways:
  1. Workflow Automation is the New Frontier: The real value of AI in developer tools comes from orchestrating entire workflows, not just individual point solutions.
  2. Embed for Adoption: Tools must integrate seamlessly into existing workflows and IDEs (like Cursor) to achieve high usage.
  3. Support as a Code-Shipping Powerhouse: Empowering non-traditional roles with AI-driven code generation leverages their unique, real-time context, creating significant operational leverage.
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December 17, 2025

Code World Model: Building World Models for Computation – Jacob Kahn, FAIR Meta

AI Engineer

AI
Key Takeaways:
  1. Semantic Shift: The future of AI in code moves from text generation to deep semantic understanding and execution simulation.
  2. Builder Opportunity: Develop next-generation debugging tools and code agents that leverage internal simulation for faster, more efficient development cycles.
  3. Investor Focus: Prioritize models and platforms that demonstrate explicit execution modeling, as this capability will redefine software development and create new market leaders.
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December 17, 2025

AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs

AI Engineer

AI
Key Takeaways:
  1. Infrastructure Shift: AI-driven kernel optimization addresses a critical bottleneck in scaling AI compute, enabling more efficient use of diverse hardware.
  2. Builder/Investor Note: Focus on solutions with robust, hardware-verified performance metrics and a clear human-in-the-loop strategy. AI is a powerful tool for automating optimization, not a magic bullet for novel algorithmic breakthroughs.
  3. The "So What?": This technology frees expert engineers from tedious optimization, allowing them to focus on higher-level research and truly innovative algorithmic design, accelerating the pace of AI development in the next 6-12 months.
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December 16, 2025

Finding The 1% of Stocks That Matter | Henry Ellenbogen Interview

Invest Like The Best

AI
Key Takeaways:
  1. Strategic Implication: The era of "free money" inflated the number of perceived compounders; a return to positive real rates demands a sharper focus on businesses demonstrating genuine financial discipline and competitive advantage.
  2. Builder/Investor Note: Seek out "Act 2" entrepreneurs and companies that can leverage AI to transform existing physical or IP-based advantages, not just create new AI products. Be prepared to buy more when market sentiment turns negative on strong businesses.
  3. The "So What?": The next 6-12 months will differentiate companies that merely adopt AI from those that strategically integrate it to build durable, uncatchable cost and distribution advantages.
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December 17, 2025

“How We Can Eliminate Crime” | Ben Horowitz and Garrett Langley

a16z

AI
Key Takeaways:
  1. The Future of Policing is Intelligent: Integrating AI, drones, and smart cameras creates a precise, accountable, and safer policing model for both officers and communities.
  2. Invest in the "How": Builders and investors should focus on technologies that enhance certainty of capture, streamline judicial processes, and support public-private partnerships to modernize urban safety infrastructure.
  3. Safety Fuels Mobility: Eliminating crime is not just about law enforcement; it's about restoring the fundamental safety required for economic mobility and a functional society.
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December 18, 2025

Two Futures | Runtime 2025

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next decade's value will accrue to those building foundational AI infrastructure and the "invisible layers" that connect intelligent systems.
  2. Builder/Investor Note: Focus capital and talent on core AI models, specialized domain intelligence, and the underlying computational fabric. Superficial applications risk rapid commoditization.
  3. The So What?: This is the defining period for the architecture of global intelligence. Participation now determines future influence and relevance.
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December 16, 2025

⚡️Jailbreaking AGI: Pliny the Liberator & John V on Red Teaming, BT6, and the Future of AI Security

Latent Space

AI
Key Takeaways:
  1. Strategic Shift: AI security must move beyond superficial guardrails to a full-stack, offensive red-teaming approach that accounts for the expanding attack surface of AI agents and their tool access.
  2. Builder/Investor Note: Builders should prioritize integrating offensive security early in development. Investors should be wary of "security theater" and favor solutions that embrace open-source collaboration and address the entire AI application stack.
  3. The "So What?": The accelerating pace of AI development means static security solutions will quickly become obsolete. Proactive, community-driven, and full-stack security research is essential for navigating the next 6-12 months of AI evolution.
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Crypto Podcasts

May 23, 2025

Entering Ethereum’s New Era | Tomasz Stańczak

Bell Curve

Crypto
Key Takeaways:
  1. Aggressive Scaling is Non-Negotiable: The EF is committed to exponential L1 scaling to support a vastly larger on-chain economy.
  2. TradFi Integration is Here: Ethereum is the prime venue for tokenizing real-world assets, bridging traditional finance with decentralized systems.
  3. A Renewed "Winning" Culture: The EF is adopting a more proactive, delivery-focused approach to ensure Ethereum's continued leadership and impact.
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May 23, 2025

Entering Ethereum’s New Era | Tomasz Stańczak

Empire

Crypto
Key Takeaways:
  1. Aggressive Execution: The Ethereum Foundation is adopting a "winning" mindset, prioritizing product delivery, engineering excellence, and rapid scaling (e.g., 3x annual gas limit increases).
  2. Deepening Capital Markets: Ethereum is solidifying its position as the primary settlement layer for RWAs and the burgeoning on-chain finance sector, attracting significant institutional interest.
  3. Innovation Frontier: Expect new waves of innovation in NFTs (tied to RWAs and AI) and enhanced L2 interoperability, driven by advancements like real-time ZK proofs.
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May 23, 2025

What’s Next for Our Precious Stablecoins?

blocmates.

Crypto
Key Takeaways:
  1. Stablecoin Shake-Up Looms: Circle's potential sale to Coinbase or Ripple could either fortify Tether's dominance or usher in a new, more controlled USDC, fundamentally altering the competitive landscape.
  2. Decentralization vs. Control: The Sui network freeze post-hack forces a hard look at crypto's soul—is absolute decentralization viable, or will pragmatic interventions become the norm?
  3. Institutional Inflows Demand Real Value: Beyond Bitcoin, the survival and growth of stablecoins and altcoins hinge on delivering tangible utility and robust security, not just speculative narratives.
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May 23, 2025

Bitcoin Hits New All-Time High! Is the Real Crypto Pump Still Ahead?

Bankless

Crypto
Key Takeaways:
  1. Stablecoin Clarity Fuels Growth: The likely passage of the "Genius Act" in the US will legitimize stablecoins, potentially unlocking trillions in value and significantly benefiting platforms like Ethereum, the current stablecoin hub.
  2. Macro Uncertainty Boosts Bitcoin: Waning confidence in traditional assets like US bonds, driven by deficit concerns, is reinforcing Bitcoin's narrative as "digital gold" and a viable alternative store of value.
  3. L1 Scaling Unlocks Potential: Ethereum's ZK breakthroughs and Solana's consensus upgrades promise dramatically increased throughput and reduced latency, critical for supporting mainstream applications and the next wave of DeFi innovation.
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May 23, 2025

The Lads Return for the BTC ATH!

Steady Lads Podcast

Crypto
Key Takeaways:
  1. **Bitcoin's Lindy Metric:** Bitcoin's "event-based" exposure relative to gold (currently ~10%) is a novel valuation framework, projected to grow ~5.5% annually.
  2. **Value vs. Hype:** While memecoins and speculative plays surge, assets like Hyperliquid demonstrating tangible cash flow are setting new standards for token utility.
  3. **Sustainable Alpha:** Long-term strategic patience and ethical conduct offer more sustainable success than short-term, "degenerate" trading tactics, with a future focus on real PE ratios for tokens promising fairer markets.
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May 23, 2025

Crypto's Next DePIN Catalyst With David Rhodus, Pipe Network

Lightspeed

Crypto
Key Takeaways:
  1. Performance First: Pipe's core bet is that significantly lower latency (single-digit milliseconds) via hyper-local nodes will provide a compelling performance advantage over incumbent CDNs.
  2. Work, Not Just Presence: The "proof of work" model, rewarding actual bandwidth egress (verified by ZKTCP) rather than mere uptime, aligns incentives directly with network value creation.
  3. Pragmatic Decentralization: Pipe leverages Solana for its current strengths but aims for product-market fit with Web2 clients first, seeing crypto as an enabling layer for a better, faster, and potentially cheaper CDN service, especially for underserved markets and emerging AI applications.
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