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AI Podcasts

November 17, 2025

Hash Rate - Ep 145 - TAO Subnets Templar (3), Basilica (39), Grail (81)

Hash Rate pod - Bittensor $TAO & Subnets

AI
Key Takeaways:
  1. **A New Market is Born:** Templar isn't just cheaper; it enables something that was previously impossible for 99% of the world. Democratizing pre-training means anyone can build a truly custom, sovereign AI.
  2. **Productization is Underway:** Covenant is no longer just a research project. With enterprise sales in motion, the focus is now on revenue. The team has committed that 100% of fees from custom training will be used to buy back its tokens.
  3. **Economics are Being Rewritten:** Basilica’s incentive mechanism is a direct critique of unsustainable models on other compute subnets. Its focus on profitability and positive TAO flow sets a new standard for economic design on Bittensor.
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November 17, 2025

Bryan Johnson: Don’t Die, Beating Entropy, AI Alignment & The Two-Species Future

Bankless

AI
Key Takeaways:
  1. AI Forces a Moral Reboot. The emergence of superintelligence renders our current societal goals dangerously obsolete. Survival must become the new prime directive.
  2. Existence is a Team Sport. The "Don't Die" philosophy is a collective mission ("we don't die") to ensure species-wide survival, not a selfish quest for individual immortality.
  3. Prepare for the Biological Sandbox. Humanity is moving from manipulating physical atoms and digital bits to programming our own biology—a frontier with both unimaginable potential and catastrophic risk.
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November 17, 2025

Emmett Shear on Building AI That Actually Cares: Beyond Control and Steering

a16z

AI
Key Takeaways:
  1. Stop Trying to “Steer” AGI. The control paradigm is a dead end. The goal isn’t a more obedient tool; it’s a trustworthy teammate. We must shift from engineering control to cultivating care.
  2. Alignment is a Process, Not a Product. True alignment isn't a fixed set of rules. It’s a dynamic process of moral learning, akin to raising a child. AIs that only follow rules are brittle and dangerous.
  3. Build for Cooperation, Not Command. The technical path forward involves training AIs in rich, multi-agent environments where they must learn cooperation and theory of mind—the foundational skills for becoming a good member of a group.
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November 16, 2025

Rawson Haverty presents "US & China AI: Lessons from Across the Pacific" | dAGI Summit 2025

Delphi Digital

AI
Key Takeaways:
  1. US Leads in Capital-Intensive Frontier AI; China Excels at Industrial Diffusion. The US leverages deep capital markets for its massive compute buildout and AGI research, while China uses state direction to embed AI into its vast industrial base via open-source models and hardware.
  2. Market Structure Dictates AI Strategy. The US "efficient oligopoly" model prioritizes global dominance and profit reinvestment by a few players. China's "subjugated swarm" model creates intense domestic competition, driving down prices and accelerating adoption at the cost of profitability.
  3. Geopolitical Tension May Be a Necessary Stabilizer. The competition between the US's freedom-oriented, frontier-pushing approach and China's stability-focused, diffusion-driven model creates a complementary tension that could be essential for navigating the "narrow corridor" between AI-driven totalitarianism and uncontrollable chaos.
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November 13, 2025

How Will AI Change Gaming Development? (A Dev’s Take)

The DCo Podcast

AI
Key Takeaways:
  1. Development timelines are collapsing from months to days. AI allows developers to swap entire asset libraries or generate new game concepts at unprecedented speed, turning a two-month art project into a day's work.
  2. The lifespan of any single game is shrinking. Prepare for a world of disposable entertainment. As AI floods the market with content, the strategy will pivot from creating one long-lasting hit to deploying a rapid succession of engaging experiences.
  3. Games are the next evolution of the attention economy. Just as memes became a core tool for community-building around tokens, easily created games will be the next engine for capturing and directing user attention in a hyper-competitive digital world.
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November 11, 2025

AI Nerves, Crypto Realism, Privacy Coins, & Lessons From Trading

1000x Podcast

AI
Key Takeaways:
  1. Adopt a Stock Picker's Mentality. The crypto market is no longer a monolith where a rising tide lifts all boats. Focus on assets with real products, user growth, and cash flow, as the gap between winners and losers will only widen.
  2. Shorting is a Tactical Assault, Not a Siege. Don't "invest" in a short. The only viable short strategies are tactical, targeting specific events like VC unlocks or news-driven spikes. Otherwise, even "total scams" can 5x against you.
  3. Cultivate a Goldfish's Memory. The most critical trading skill is learning how to change your mind. Cut losing trades, forget the loss (but remember the lesson), and redeploy capital without emotional baggage. Stubbornness is a portfolio killer.
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November 11, 2025

Grant Lee: Building Gamma’s AI Presentation Company to 100 Million Users

a16z

AI
Key Takeaways:
  1. Word-of-mouth isn't a feature; it's the engine. Before spending a dime on marketing, obsess over the first 30 seconds of the user experience until people can't help but share it.
  2. Being different is better than being better. Don't build incrementally better slideware. Redefine the core primitives of your category, as Gamma did by moving beyond the 16x9 slide.
  3. Hire painfully slowly to protect your DNA. Resisting the temptation to scale headcount with user growth is a superpower. The goal isn't to hit a hiring target; it's to hire the best people.
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November 7, 2025

Amjad Masad & Adam D’Angelo: How Far Are We From AGI?

a16z

AI
Key Takeaways:
  1. AGI Is a Definitional Debate. Progress toward an AI that can replace a remote worker is happening fast. However, achieving "true" human-like learning efficiency may require an entirely new paradigm beyond scaling current LLMs.
  2. The New Creator Economy Is Code. AI is turning software development into a mainstream creative pursuit, empowering a new class of solo entrepreneurs who can build what previously required entire teams.
  3. Incumbents Learned Their Lesson. Unlike past tech shifts, today's giants are aggressively adopting AI, making it both a sustaining *and* disruptive force. The market is large enough for both incumbents and startups to create massive value.
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November 6, 2025

Mark Zuckerberg & Priscilla Chan: How AI Will Cure All Disease

a16z

AI
Key Takeaways:
  1. Build the Tools, Not Just the House: CZI’s greatest leverage comes from creating open-source tools and datasets. By building the fundamental infrastructure, they empower the entire scientific community—from academic labs to startups—to accelerate discovery.
  2. Data Is the New Microscope: The future of biology hinges on a tight feedback loop between generating novel, purpose-built datasets and training domain-specific AI models on them. This synergy is unlocking insights that were previously impossible.
  3. Virtual Biology Is the Next Frontier: Simulating biology computationally with "virtual cells" will become the new standard for research, enabling scientists to test riskier hypotheses faster and cheaper, dramatically compressing the timeline for major breakthroughs.
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Crypto Podcasts

February 13, 2026

Aave Governance, Polymarket, and LayerZero’s Zero Chain | Livestream

0xResearch

Crypto
Key Takeaways:
  1. DeFi protocols are confronting the trade-off between pure decentralization and operational efficiency.
  2. Identify protocols that effectively bridge crypto's core strengths with traditional finance's distribution and user experience.
  3. The next 6-12 months will see a clearer divergence between protocols that successfully adapt their governance and business models for growth.
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February 13, 2026

Bittensor Novelty Search :: Network Governance

The Opentensor Foundation | Bittensor TAO

Crypto
Key Takeaways:
  1. Bittensor is shifting from a founder-led project to a fully decentralized, community-governed AI network.
  2. Participate in upcoming governance votes and discussions, especially regarding emission control and subnet performance.
  3. Bittensor is transitioning from a founder-led project to a community-owned, self-defending AI utility.
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February 13, 2026

Stepping Down as CEO to Subnet Owner — Bittensor Is Going Fully Decentralized

The Opentensor Foundation | Bittensor TAO

Crypto
Key Takeaways:
  1. The future of AI ownership is shifting from corporate silos to decentralized, community-governed networks.
  2. Engage with Bittensor's governance.
  3. Bittensor is transitioning from a founder-led project to a truly self-sovereign AI network.
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February 13, 2026

Bittensor Cofounder Explains What Makes a Great Subnet

The Opentensor Foundation | Bittensor TAO

Crypto
Key Takeaways:
  1. The shift from centralized AI development to decentralized, incentive-driven networks like Bittensor demands a rigorous focus on economic mechanism design. The core challenge is translating a desired AI capability into a quantifiable, ungameable benchmark that ensures genuine progress, not just benchmark-specific optimization.
  2. Prioritize benchmark design and transparency. Builders should immediately define a precise, copy-resistant, and low-variance benchmark, then launch on mainnet quickly with open-source validator code.
  3. Over the next 6-12 months, the subnets that win will be those that master incentive alignment through robust, transparent benchmarking and rapid, mainnet-first iteration. Investors should look for subnets demonstrating clear auditability and a willingness to confront and fix miner exploits openly, as these indicate long-term viability and genuine progress towards their stated AI goals.
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February 13, 2026

Has Crypto Lost the Plot? Bear Market Reality & What Happens Next

Bankless

Crypto
Key Takeaways:
  1. The industry is undergoing a forced re-alignment, moving from a broad "world computer" vision to a focused "financial utility machine" reality. This means capital and talent are increasingly flowing to projects that deliver tangible financial value and robust infrastructure.
  2. Prioritize projects building core financial primitives, robust L1/L2 infrastructure, or those leveraging AI for financial automation. Investigate prediction market platforms and their regulatory positioning, as they represent a proven, high-growth revenue stream.
  3. The current market downturn is a cleansing fire, forcing crypto to shed non-viable narratives and double down on its core strength: programmable finance. Success will accrue to those who build for financial utility and AI-driven users, not just human consumers.
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February 13, 2026

Solana’s Changing Market Microstructure

Lightspeed

Crypto
Key Takeaways:
  1. The pursuit of optimal market microstructure is driving a wedge between L1s and specialized execution environments, forcing L1s like Solana to either adapt their core protocol or risk losing high-value DeFi activity to custom solutions.
  2. Monitor Solana's validator stake distribution for Jito's BAM and Harmonic, as increasing adoption of MEV-mitigating clients will directly impact onchain trading profitability and the viability of sophisticated DeFi applications.
  3. Solana's ability to scale throughput and implement protocol-enforced MEV solutions will determine if it can reclaim its position as the preferred L1 for high-frequency DeFi, or if specialized applications will continue to build off-chain, fragmenting the ecosystem.
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