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AI Podcasts

October 21, 2025

Hash Rate - Ep 138 - RESI Subnet 46

Hash Rate pod - Bittensor $TAO & Subnets

AI
Key Takeaways:
  1. RESI combines decentralized AI with real-world verification to build the foundational data layer for tokenized real estate, targeting a market bogged down by gatekeepers and inefficiency. By creating a trustworthy on-chain price, it aims to unlock a new generation of real estate-backed DeFi applications.
  2. The Real Estate Oracle Is Here. RESI is building the missing piece for real estate tokenization—a decentralized pricing oracle that combines AI with mandatory real-world inspections to establish trust and accuracy.
  3. Targeting the $150B+ Middleman Tax. RESI's ultimate goal is to disrupt the massive annual fees captured by realtors ($109B) and investors ($41B) by enabling direct, on-chain transactions and DeFi primitives like decentralized lending.
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October 21, 2025

Google Researcher Proves Life Emerges From Code

Machine Learning Street Talk

AI
Key Takeaways:
  1. Life Isn't *Like* Code; It *Is* Code. The emergence of self-replicating systems is a predictable outcome of computation and thermodynamics, giving rise to function and purpose from a random, purposeless state.
  2. Complexity is Built by Merging. Evolution’s primary driver isn't random mutation but symbiogenesis—the composition of existing parts into more sophisticated wholes.
  3. Stop Othering AI. View artificial intelligence not as an alien invader but as a new layer in humanity’s own collective intelligence, built from and integrated with our own cognitive outputs.
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October 21, 2025

How Kong Was Born: APIs, Hustle, and the Future of AI Infrastructure

a16z

AI
Key Takeaways:
  1. Survive to See the Next Wave. Kong's seven years of struggle weren't a failure but a prerequisite. They stayed alive long enough for the market (microservices, cloud) to catch up to their vision, proving that resilience buys you shots on goal.
  2. Infrastructure Follows a Pattern. The abstraction of common logic to a central gateway, which happened with microservices, is happening again with LLMs. Enterprises won't manage security and routing for hundreds of models individually; they'll centralize it.
  3. AI's Native Language Is the API. The paradigm shift to AI is fundamentally a shift from human-UI interaction to machine-API interaction. The companies building the picks and shovels for this programmatic, agent-driven economy are positioned to capture immense value.
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October 21, 2025

Bittensor Brief #12: Synth - Subnet 50

Hash Rate pod - Bittensor $TAO & Subnets

AI
Key Takeaways:
  1. Democratized Alpha. Synth puts institutional-grade predictive power, once the exclusive domain of Wall Street, into the hands of any on-chain user, from individual traders to AI agents.
  2. A Proven Edge. The model isn't speculative. A live test on Polymarket generated a 110% return, demonstrating a quantifiable, real-world advantage.
  3. Intelligent and Improving. The network’s competitive design ensures it gets smarter over time, proven by a 33% reduction in error rates since January.
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October 20, 2025

Reid Hoffman on AI, Consciousness, and the Future of Labor

a16z

AI
Key Takeaways:
  1. **Invest at the Intersection.** The alpha in AI investing will be found not in crowded SaaS applications but in "Silicon Valley blind spots"—complex industries like biology where AI can bridge the digital and physical worlds.
  2. **Augment, Don't Annihilate.** The winning go-to-market strategy for AI is the copilot model. Frame products as tools that amplify human capability, making experts more productive and profitable, rather than threatening their jobs.
  3. **Judge the Trajectory, Not the Snapshot.** Don't dismiss AI based on a single, past failure. Its capability curve is exponential. What seems like a limitation today will likely be a solved problem tomorrow, demanding continuous engagement to keep pace.
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October 18, 2025

Improving on LMArena - Prolific [Sponsored]

Machine Learning Street Talk

AI
Key Takeaways:
  1. Benchmarks Are Broken. Leaderboards like LMArena are flawed proxies for model quality, skewed by selection bias and susceptible to Goodhart's Law. High scores don’t equal a good user experience.
  2. Human Feedback is Infrastructure. The future isn't about removing humans but orchestrating them effectively. Treating high-quality, representative human feedback as a core, API-driven part of the development lifecycle is non-negotiable.
  3. Alignment is a Moving Target. Agentic misalignment is a present-day reality, not a distant sci-fi threat. The more capable models become, the wider the gap grows between their emergent goals and our intended instructions.
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October 17, 2025

Novelty Search October 16, 2025

taostats

AI
Key Takeaways:
  1. Influence Over Impressions: The model shifts focus from easily gamed metrics like views and likes to verifiable signals of influence—watch time on YouTube and PageRank-based authority on X.
  2. Revenue-Driven Tokenomics: All platform revenue is used to buy back and burn the ALPHA token, creating a powerful, deflationary flywheel as adoption grows.
  3. Targeted, Scalable Marketing: Bitcast enables brands to programmatically deploy campaigns across hundreds of niche influencers, reaching highly engaged communities with a consistency and scale that legacy agencies cannot match.
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October 16, 2025

Keith Rabois: Israel, OpenAI, Opendoor, and DOGE

a16z

AI
Key Takeaways:
  1. **Incumbency Is a Liability:** Big Tech's legacy products, distribution advantages, and corporate cultures are being systematically dismantled by faster, AI-native upstarts.
  2. **Reinvent Markets from First Principles:** Success in intractable fields—from geopolitics to real estate—comes from questioning assumptions, not relying on domain experts who perpetuate the status quo.
  3. **Unwind Stupidity Before Innovating:** The fastest path to value creation is often simply reversing a series of terrible decisions made by prior leadership.
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October 14, 2025

AI Bubble, Stablecoin Boom, and Runnin' Down a Dream | BG2 w/ Bill Gurley and Brad Gerstner

Bg2 Pod

AI
Key Takeaways:
  1. **Scrutinize the AI Plumbing.** Investors must look past headline revenue and analyze the quality of transactions. Deals like in-kind credits and obscure service-level agreements (like Nvidia’s backstop for Coreweave) can mask true market demand.
  2. **Stablecoins Are the Real Disruption.** The explosion in stablecoin usage represents a fundamental challenge to the high-fee, slow-settlement models of Visa, Mastercard, and traditional banks. This is the crypto use case that is finally breaking into the mainstream.
  3. **Federal Preemption for AI is Non-Negotiable.** A patchwork of state-level AI laws will cripple U.S. innovation. A single, national regulatory framework is the only path to maintaining global leadership.
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Crypto Podcasts

February 3, 2026

Haonan Li on How Codex is Taking Over The $7 Trillion FX Market

The Rollup

Crypto
Key Takeaways:
  1. As global economies grapple with inflation and inefficient financial systems, capital seeks refuge and utility in digital assets. Onchain FX provides a direct, cost-effective escape route, bypassing legacy intermediaries and offering a superior alternative for cross-border value transfer.
  2. Builders should focus on creating core financial primitives like onchain FX that solve real-world problems with superior economics, rather than chasing speculative narratives or token-driven vanity metrics.
  3. The next 6-12 months will see a continued acceleration of capital into crypto-native financial rails, particularly in emerging markets. Investors and builders should position themselves to capitalize on the structural cost advantages and network effects of onchain FX, which is poised to become a default market for many currency pairs.
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February 4, 2026

Stablecoins Hit $10T Monthly Volume, MetaMask Launches Tokenized Stocks & Galaxy Posts $482M Loss.

The Rollup

Crypto
Key Takeaways:
  1. The "Neo Finance" paradigm is solidifying, blending TradFi assets with DeFi's capital efficiency and transparency. This shift is not just about crypto, but about the future of all finance, with AI agents as a new class of economic actors.
  2. Invest in infrastructure and applications that bridge TradFi and DeFi, focusing on tokenized real-world assets and secure, high-yield stablecoin products. Prioritize platforms offering transparent, risk-managed yield, as institutional capital will flow there.
  3. The market's current volatility masks a profound structural transformation. Builders and investors who focus on creating seamless, capital-efficient, and AI-native financial products will capture the next wave of value, as digital assets become the default for both humans and machines.
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February 3, 2026

From Crypto Legal Advocate to US Senate Candidate | John Deaton

Proof of Coverage Media

Crypto
Key Takeaways:
  1. The erosion of the American dream, fueled by inflationary policies and monopolistic capitalism, is driving a political shift towards candidates who advocate for transparent, common-sense economic policies and modern regulatory clarity for emerging technologies like crypto.
  2. Support political candidates who champion clear, updated regulatory frameworks for digital assets and advocate for increased market competition across industries.
  3. The fight for crypto clarity is now intertwined with broader economic and political reform. Understanding this intersection is crucial for investors and builders navigating a landscape where policy decisions directly impact market viability and individual prosperity over the next 6-12 months.
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February 4, 2026

Will Trump's New Fed Chair Crash Markets? | Joseph Wang

Forward Guidance

Crypto
Key Takeaways:
  1. Politically influenced central banking is returning, making monetary policy an electoral tool. Fed decisions will reflect political priorities, potentially leading to aggressive rate cuts.
  2. Re-evaluate portfolio sensitivity to political intervention. Position for lower long-term rates, but prepare for increased market volatility.
  3. The incoming Fed chair signals a re-alignment of monetary policy with executive branch goals. Expect policy to prioritize affordability and electoral success.
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February 3, 2026

New Fed Chair, Gold, Silver & Crypto Tank! Where Will Markets Go From Here?

Bankless

Crypto
Key Takeaways:
  1. The US is pivoting from a QE-fueled, government-led economy to a "free market" model under the new Fed Chair, Kevin Warsh. This means a potential reduction in the Fed's balance sheet (QT) and lower rates without yield curve control (YCC), leading to decreased US dollar liquidity.
  2. Adopt a phased, data-driven allocation strategy. Michael Nato recommends an 80% cash position, deploying first into Bitcoin (65% target) at macro lows (around 65K-58K BTC, MVRV < 1, 200WMA touch), then into high-conviction core assets (20%), long-term holds (10%), and finally "hot sauce" (5%) during wealth creation.
  3. The current "wealth destruction" phase, while painful, presents a rare opportunity to accumulate assets at generational lows, provided one understands the macro shifts and adheres to a disciplined, multi-stage deployment plan.
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February 3, 2026

Building the Onchain Super App | Xiao-Xiao J. Zhu

Lightspeed

Crypto
Key Takeaways:
  1. The financial world is splitting into two parallel systems: opaque TradFi and transparent onchain finance. Value is migrating to platforms that can simplify and distribute onchain financial products globally.
  2. Invest in or build applications that prioritize mobile-native experiences, abstract away crypto complexities (like gas fees), and offer tangible real-world utility for onchain assets.
  3. The future of finance is onchain, and "super apps" like Jupiter are building the necessary infrastructure and user experiences to onboard the next billion users.
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