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AI Podcasts

December 17, 2025

AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs

AI Engineer

AI
Key Takeaways:
  1. Strategic Shift: AI-driven kernel generation is not replacing human genius but augmenting it, allowing experts to focus on novel breakthroughs while AI automates the application of known optimizations across a complex hardware landscape.
  2. Builder/Investor Note: Focus on robust validation and hardware-in-the-loop systems. Claims of "AI inventing new algorithms" in this domain are premature. The real value is in automating the "bag of tricks" for heterogeneous compute.
  3. The "So What?": This technology is critical for scaling agentic AI workloads. Expect significant investment in tools that abstract hardware complexity and enable efficient, automated optimization, driving down the cost of AI inference in the next 6-12 months.
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December 17, 2025

Code World Model: Building World Models for Computation – Jacob Kahn, FAIR Meta

AI Engineer

AI
Key Takeaways:
  1. Semantic Shift: The future of AI in code moves from text generation to deep semantic understanding and execution simulation.
  2. Builder Opportunity: Develop next-generation debugging tools and code agents that leverage internal simulation for faster, more efficient development cycles.
  3. Investor Focus: Prioritize models and platforms that demonstrate explicit execution modeling, as this capability will redefine software development and create new market leaders.
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December 17, 2025

AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs

AI Engineer

AI
Key Takeaways:
  1. Infrastructure Shift: AI-driven kernel optimization addresses a critical bottleneck in scaling AI compute, enabling more efficient use of diverse hardware.
  2. Builder/Investor Note: Focus on solutions with robust, hardware-verified performance metrics and a clear human-in-the-loop strategy. AI is a powerful tool for automating optimization, not a magic bullet for novel algorithmic breakthroughs.
  3. The "So What?": This technology frees expert engineers from tedious optimization, allowing them to focus on higher-level research and truly innovative algorithmic design, accelerating the pace of AI development in the next 6-12 months.
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December 17, 2025

“How We Can Eliminate Crime” | Ben Horowitz and Garrett Langley

a16z

AI
Key Takeaways:
  1. Effective crime reduction requires a shift from reactive punishment to proactive, intelligence-driven deterrence, making it highly probable for criminals to be caught.
  2. The market for AI-powered public safety technology, particularly solutions that integrate data for precision and accountability, presents a significant opportunity. Public-private partnerships are a key funding mechanism.
  3. Over the next 6-12 months, expect to see more cities adopt advanced surveillance and AI tools, driven by private funding, as they seek to improve safety and address staffing shortages without resorting to ineffective, broad-stroke policies.
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December 17, 2025

“How We Can Eliminate Crime” | Ben Horowitz and Garrett Langley

a16z

AI
Key Takeaways:
  1. The Future of Policing is Intelligent: Integrating AI, drones, and smart cameras creates a precise, accountable, and safer policing model for both officers and communities.
  2. Invest in the "How": Builders and investors should focus on technologies that enhance certainty of capture, streamline judicial processes, and support public-private partnerships to modernize urban safety infrastructure.
  3. Safety Fuels Mobility: Eliminating crime is not just about law enforcement; it's about restoring the fundamental safety required for economic mobility and a functional society.
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December 16, 2025

Build reliable AI agents using W&B Training

Weights & Biases

AI
Key Takeaways:
  1. The democratization of RL fine-tuning will accelerate the development and deployment of more reliable and sophisticated AI agents across industries.
  2. Builders should explore open-source LLMs combined with RL fine-tuning as a cost-effective strategy to achieve specific performance benchmarks, especially where latency and cost are critical.
  3. Platforms abstracting infrastructure complexity and providing integrated tooling for the entire AI development lifecycle are crucial for the next phase of AI agent deployment.
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December 16, 2025

Build reliable AI agents using W&B Training

Weights & Biases

AI
Key Takeaways:
  1. The democratization of RL for LLMs will accelerate the deployment of more reliable and sophisticated AI agents across industries.
  2. Builders should move beyond basic prompt engineering and RAG. RL fine-tuning, now accessible via W&B Serverless RL, is a critical next step for high-stakes agentic applications.
  3. For the next 6-12 months, expect a surge in production-grade AI agents, with open-source models increasingly closing the performance gap with proprietary alternatives through advanced fine-tuning.
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December 16, 2025

Your Support Team Should Ship Code – Lisa Orr, Zapier

AI Engineer

AI
Key Takeaways:
  1. Workflow Automation is the New Frontier: The real value of AI in developer tools comes from orchestrating entire workflows, not just individual point solutions.
  2. Embed for Adoption: Tools must integrate seamlessly into existing workflows and IDEs (like Cursor) to achieve high usage.
  3. Support as a Code-Shipping Powerhouse: Empowering non-traditional roles with AI-driven code generation leverages their unique, real-time context, creating significant operational leverage.
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December 16, 2025

Your Support Team Should Ship Code – Lisa Orr, Zapier

AI Engineer

AI
Key Takeaways:
  1. Strategic Implication: Companies integrating AI-driven code generation into non-engineering roles will see significant efficiency gains and improved product reliability.
  2. Builder/Investor Note: Focus on building AI tools that deeply embed into existing workflows. Orchestration of multiple AI tools into an agent-like system is key for adoption and value.
  3. The "So What?": The next 6-12 months will see a redefinition of "support" from reactive reporting to proactive, code-shipping problem-solving, unlocking new talent pools and accelerating development cycles.
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Crypto Podcasts

December 14, 2025

The Hidden Cost of Zero-Fee DEX's

The Gwart Show

Crypto
Key Takeaways:
  1. Strategic Shift: The Perp DEX market is maturing beyond raw volume. Sustainable competitive advantages will come from transparent economics, innovative collateral, and robust on-chain security.
  2. Builder/Investor Note: Focus on projects solving the retail onboarding problem and those building sophisticated, yield-bearing, or cross-asset collateral systems with sound liquidation mechanics.
  3. The "So What?": Expect market consolidation over the next 5 years, with a handful of dominant Perp DEXs emerging, mirroring the CeFi landscape. Innovation in core primitives, not just new markets, will define the winners.
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December 13, 2025

Why This Token Launch Is Different

The Rollup

Crypto
Key Takeaways:
  1. Community First: Prioritizing the community through token allocation and buybacks fosters a stronger, more engaged user base from the outset.
  2. Utility Over Hype: Launching with immediate, tangible utility drives genuine adoption and long-term value creation.
  3. Ecosystem Growth: Continuously expanding the ecosystem with new features and integrations ensures sustained relevance and attracts a broader audience.
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December 12, 2025

Rate Cuts! ETH’s Comeback? & All Markets Going Onchain?

Bankless

Crypto
Key Takeaways:
  1. ETH is positioned for a potential resurgence fueled by technological advancements, institutional investment, and a shift in market sentiment away from solely favoring Solana, mimicking Bitcoin’s rise in the 2021 cycle.
  2. ZK technology is fundamentally changing the Layer 2 landscape, unifying liquidity and enabling seamless interaction with Layer 1, which may lead to standardized infrastructure and increased institutional adoption.
  3. Regulatory winds are shifting, with agencies embracing crypto, banks legitimizing Bitcoin as collateral, and the potential passage of the Clarity Act paving the way for Wall Street's tokenization efforts.
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December 11, 2025

Maciej Kula: Bittensor Halvings, Chain Buys, TaoFlow, Latent Holdings, LearnBittensor | Ep. 76

Ventura Labs

Crypto
Key Takeaways:
  1. Focus on understanding the fundamentals of incentive mechanisms, not just surface-level information, to adapt to Bittensor's frequent changes.
  2. Proxy wallets will enhance security by allowing users to isolate activities and protect their primary wallets.
  3. Monitor subnet inflows to understand the impact of TaoFlow and identify potential opportunities or risks.
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December 11, 2025

The Airdrop Mistake Luca Netz Won’t Repeat

The DCo Podcast

Crypto
Key Takeaways:
  1. Prioritize Early Alignment: To benefit from Abstract's ecosystem rewards, demonstrate commitment now, not right before a potential airdrop.
  2. Community Over Opportunism: Future rewards will favor genuine holders and active community members over short-term profit seekers.
  3. No Second Chances: Don't expect warnings or sympathy if you try to "grift" the system; Netz is committed to protecting loyal users.
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December 11, 2025

The Return of Corporate Blockchains | Roundup

Bell Curve

Crypto
Key Takeaways:
  1. Enterprise blockchains are making a comeback by embracing crypto, not avoiding it, marking a significant shift from the failed attempts of 2018.
  2. The success of corporate chains hinges on strategic focus, prioritizing ecosystems and BD, over trying to dominate the entire value chain, as too much control can stifle innovation.
  3. Public, permissionless blockchains must remain relevant by continually finding product-market fit in emerging segments to maintain their monetary premium amid increasing competition from verticalized corporate chains.
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