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AI Podcasts

December 17, 2025

Rethinking Pre-Training for Agentic AI [Aakanksha Chowdhery] - 759

The TWIML AI Podcast with Sam Charrington

AI
Key Takeaways:
  1. Pre-Training is the New Frontier: The next leap in AI capabilities, particularly for agentic systems, will come from fundamental advancements in pre-training, not just post-training tweaks.
  2. Builders & Investors: Focus on teams rethinking loss objectives, curating high-quality reasoning data, and developing dynamic benchmarks for agentic capabilities. Be wary of "agentic" claims that lack foundational pre-training innovation.
  3. The "So What?": Over the next 6-12 months, expect a push for new benchmarks and data strategies that explicitly train models for multi-step planning, long-form reasoning, and error recovery, moving beyond simple next-token prediction.
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December 16, 2025

What We Learned Deploying AI within Bloomberg’s Engineering Organization – Lei Zhang, Bloomberg

AI Engineer

AI
Key Takeaways:
  1. Strategic Implication: AI fundamentally changes the economics of software development. Organizations must re-evaluate what constitutes "high-quality" engineering and adapt their processes.
  2. Builder/Investor Note: Prioritize platforms that provide guardrails and guidance for AI tool usage, focusing on deterministic verification and robust testing. Uncontrolled AI deployment risks technical debt.
  3. The "So What?": The next 6-12 months will see a bifurcation: companies that strategically integrate AI into their engineering culture and platforms will gain significant efficiency, while those that don't will struggle with quality and adoption.
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December 16, 2025

Your Support Team Should Ship Code – Lisa Orr, Zapier

AI Engineer

AI
Key Takeaways:
  1. Workflow Automation is the New Frontier: The real value of AI in developer tools comes from orchestrating entire workflows, not just individual point solutions.
  2. Embed for Adoption: Tools must integrate seamlessly into existing workflows and IDEs (like Cursor) to achieve high usage.
  3. Support as a Code-Shipping Powerhouse: Empowering non-traditional roles with AI-driven code generation leverages their unique, real-time context, creating significant operational leverage.
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December 17, 2025

Code World Model: Building World Models for Computation – Jacob Kahn, FAIR Meta

AI Engineer

AI
Key Takeaways:
  1. Semantic Shift: The future of AI in code moves from text generation to deep semantic understanding and execution simulation.
  2. Builder Opportunity: Develop next-generation debugging tools and code agents that leverage internal simulation for faster, more efficient development cycles.
  3. Investor Focus: Prioritize models and platforms that demonstrate explicit execution modeling, as this capability will redefine software development and create new market leaders.
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December 17, 2025

AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs

AI Engineer

AI
Key Takeaways:
  1. Infrastructure Shift: AI-driven kernel optimization addresses a critical bottleneck in scaling AI compute, enabling more efficient use of diverse hardware.
  2. Builder/Investor Note: Focus on solutions with robust, hardware-verified performance metrics and a clear human-in-the-loop strategy. AI is a powerful tool for automating optimization, not a magic bullet for novel algorithmic breakthroughs.
  3. The "So What?": This technology frees expert engineers from tedious optimization, allowing them to focus on higher-level research and truly innovative algorithmic design, accelerating the pace of AI development in the next 6-12 months.
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December 16, 2025

Finding The 1% of Stocks That Matter | Henry Ellenbogen Interview

Invest Like The Best

AI
Key Takeaways:
  1. Strategic Implication: The era of "free money" inflated the number of perceived compounders; a return to positive real rates demands a sharper focus on businesses demonstrating genuine financial discipline and competitive advantage.
  2. Builder/Investor Note: Seek out "Act 2" entrepreneurs and companies that can leverage AI to transform existing physical or IP-based advantages, not just create new AI products. Be prepared to buy more when market sentiment turns negative on strong businesses.
  3. The "So What?": The next 6-12 months will differentiate companies that merely adopt AI from those that strategically integrate it to build durable, uncatchable cost and distribution advantages.
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December 17, 2025

“How We Can Eliminate Crime” | Ben Horowitz and Garrett Langley

a16z

AI
Key Takeaways:
  1. The Future of Policing is Intelligent: Integrating AI, drones, and smart cameras creates a precise, accountable, and safer policing model for both officers and communities.
  2. Invest in the "How": Builders and investors should focus on technologies that enhance certainty of capture, streamline judicial processes, and support public-private partnerships to modernize urban safety infrastructure.
  3. Safety Fuels Mobility: Eliminating crime is not just about law enforcement; it's about restoring the fundamental safety required for economic mobility and a functional society.
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December 18, 2025

Two Futures | Runtime 2025

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next decade's value will accrue to those building foundational AI infrastructure and the "invisible layers" that connect intelligent systems.
  2. Builder/Investor Note: Focus capital and talent on core AI models, specialized domain intelligence, and the underlying computational fabric. Superficial applications risk rapid commoditization.
  3. The So What?: This is the defining period for the architecture of global intelligence. Participation now determines future influence and relevance.
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December 16, 2025

⚡️Jailbreaking AGI: Pliny the Liberator & John V on Red Teaming, BT6, and the Future of AI Security

Latent Space

AI
Key Takeaways:
  1. Strategic Shift: AI security must move beyond superficial guardrails to a full-stack, offensive red-teaming approach that accounts for the expanding attack surface of AI agents and their tool access.
  2. Builder/Investor Note: Builders should prioritize integrating offensive security early in development. Investors should be wary of "security theater" and favor solutions that embrace open-source collaboration and address the entire AI application stack.
  3. The "So What?": The accelerating pace of AI development means static security solutions will quickly become obsolete. Proactive, community-driven, and full-stack security research is essential for navigating the next 6-12 months of AI evolution.
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Crypto Podcasts

February 3, 2026

From Crypto Legal Advocate to US Senate Candidate | John Deaton

Proof of Coverage Media

Crypto
Key Takeaways:
  1. The erosion of the American dream, fueled by inflationary policies and monopolistic capitalism, is driving a political shift towards candidates who advocate for transparent, common-sense economic policies and modern regulatory clarity for emerging technologies like crypto.
  2. Support political candidates who champion clear, updated regulatory frameworks for digital assets and advocate for increased market competition across industries.
  3. The fight for crypto clarity is now intertwined with broader economic and political reform. Understanding this intersection is crucial for investors and builders navigating a landscape where policy decisions directly impact market viability and individual prosperity over the next 6-12 months.
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February 4, 2026

Will Trump's New Fed Chair Crash Markets? | Joseph Wang

Forward Guidance

Crypto
Key Takeaways:
  1. Politically influenced central banking is returning, making monetary policy an electoral tool. Fed decisions will reflect political priorities, potentially leading to aggressive rate cuts.
  2. Re-evaluate portfolio sensitivity to political intervention. Position for lower long-term rates, but prepare for increased market volatility.
  3. The incoming Fed chair signals a re-alignment of monetary policy with executive branch goals. Expect policy to prioritize affordability and electoral success.
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February 3, 2026

New Fed Chair, Gold, Silver & Crypto Tank! Where Will Markets Go From Here?

Bankless

Crypto
Key Takeaways:
  1. The US is pivoting from a QE-fueled, government-led economy to a "free market" model under the new Fed Chair, Kevin Warsh. This means a potential reduction in the Fed's balance sheet (QT) and lower rates without yield curve control (YCC), leading to decreased US dollar liquidity.
  2. Adopt a phased, data-driven allocation strategy. Michael Nato recommends an 80% cash position, deploying first into Bitcoin (65% target) at macro lows (around 65K-58K BTC, MVRV < 1, 200WMA touch), then into high-conviction core assets (20%), long-term holds (10%), and finally "hot sauce" (5%) during wealth creation.
  3. The current "wealth destruction" phase, while painful, presents a rare opportunity to accumulate assets at generational lows, provided one understands the macro shifts and adheres to a disciplined, multi-stage deployment plan.
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February 3, 2026

Building the Onchain Super App | Xiao-Xiao J. Zhu

Lightspeed

Crypto
Key Takeaways:
  1. The financial world is splitting into two parallel systems: opaque TradFi and transparent onchain finance. Value is migrating to platforms that can simplify and distribute onchain financial products globally.
  2. Invest in or build applications that prioritize mobile-native experiences, abstract away crypto complexities (like gas fees), and offer tangible real-world utility for onchain assets.
  3. The future of finance is onchain, and "super apps" like Jupiter are building the necessary infrastructure and user experiences to onboard the next billion users.
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February 3, 2026

The Crypto Community Hangover w/ David Hoffman

The Gwart Show

Crypto
Key Takeaways:
  1. Crypto's initial broad vision has narrowed to specific financial use cases, while AI and traditional markets capture broader attention. This means builders must focus on tangible value and investors on proven models.
  2. Identify projects with novel token distribution models (like Cap's stablecoin airdrop) or those building consumer-friendly applications within new ecosystems (like Mega ETH) that address past tokenomics failures.
  3. The industry is past its naive, speculative phase. Success hinges on practical applications, robust tokenomics, and competing with traditional finance, not just abstract ideals.
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February 3, 2026

The Crypto Community Hangover w/ David Hoffman

The Gwart Show

Crypto
Key Takeaways:
  1. The Macro Shift: From unbridled, community-driven idealism to a pragmatic, business-focused approach. Early crypto imagined a world where "everything is a thing on Ethereum," but reality has narrowed its primary use cases to finance and trading, forcing a re-evaluation of tokenomics and community models. This shift is also driven by AI capturing mindshare and traditional finance co-opting blockchain tech.
  2. The Tactical Edge: Re-evaluate token distribution models. Instead of relying on inflationary yield farming that creates sell pressure, explore innovative approaches like Cap's "stable drop" (airdropping stablecoins, then inviting participation in a token sale) to align incentives and attract long-term holders. Focus on building real products with defensible business models, even if they lean more "business" than "protocol."
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