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AI Podcasts

October 21, 2025

Hash Rate - Ep 138 - RESI Subnet 46

Hash Rate pod - Bittensor $TAO & Subnets

AI
Key Takeaways:
  1. RESI combines decentralized AI with real-world verification to build the foundational data layer for tokenized real estate, targeting a market bogged down by gatekeepers and inefficiency. By creating a trustworthy on-chain price, it aims to unlock a new generation of real estate-backed DeFi applications.
  2. The Real Estate Oracle Is Here. RESI is building the missing piece for real estate tokenization—a decentralized pricing oracle that combines AI with mandatory real-world inspections to establish trust and accuracy.
  3. Targeting the $150B+ Middleman Tax. RESI's ultimate goal is to disrupt the massive annual fees captured by realtors ($109B) and investors ($41B) by enabling direct, on-chain transactions and DeFi primitives like decentralized lending.
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October 21, 2025

Google Researcher Proves Life Emerges From Code

Machine Learning Street Talk

AI
Key Takeaways:
  1. Life Isn't *Like* Code; It *Is* Code. The emergence of self-replicating systems is a predictable outcome of computation and thermodynamics, giving rise to function and purpose from a random, purposeless state.
  2. Complexity is Built by Merging. Evolution’s primary driver isn't random mutation but symbiogenesis—the composition of existing parts into more sophisticated wholes.
  3. Stop Othering AI. View artificial intelligence not as an alien invader but as a new layer in humanity’s own collective intelligence, built from and integrated with our own cognitive outputs.
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October 21, 2025

How Kong Was Born: APIs, Hustle, and the Future of AI Infrastructure

a16z

AI
Key Takeaways:
  1. Survive to See the Next Wave. Kong's seven years of struggle weren't a failure but a prerequisite. They stayed alive long enough for the market (microservices, cloud) to catch up to their vision, proving that resilience buys you shots on goal.
  2. Infrastructure Follows a Pattern. The abstraction of common logic to a central gateway, which happened with microservices, is happening again with LLMs. Enterprises won't manage security and routing for hundreds of models individually; they'll centralize it.
  3. AI's Native Language Is the API. The paradigm shift to AI is fundamentally a shift from human-UI interaction to machine-API interaction. The companies building the picks and shovels for this programmatic, agent-driven economy are positioned to capture immense value.
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October 21, 2025

Bittensor Brief #12: Synth - Subnet 50

Hash Rate pod - Bittensor $TAO & Subnets

AI
Key Takeaways:
  1. Democratized Alpha. Synth puts institutional-grade predictive power, once the exclusive domain of Wall Street, into the hands of any on-chain user, from individual traders to AI agents.
  2. A Proven Edge. The model isn't speculative. A live test on Polymarket generated a 110% return, demonstrating a quantifiable, real-world advantage.
  3. Intelligent and Improving. The network’s competitive design ensures it gets smarter over time, proven by a 33% reduction in error rates since January.
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October 20, 2025

Reid Hoffman on AI, Consciousness, and the Future of Labor

a16z

AI
Key Takeaways:
  1. **Invest at the Intersection.** The alpha in AI investing will be found not in crowded SaaS applications but in "Silicon Valley blind spots"—complex industries like biology where AI can bridge the digital and physical worlds.
  2. **Augment, Don't Annihilate.** The winning go-to-market strategy for AI is the copilot model. Frame products as tools that amplify human capability, making experts more productive and profitable, rather than threatening their jobs.
  3. **Judge the Trajectory, Not the Snapshot.** Don't dismiss AI based on a single, past failure. Its capability curve is exponential. What seems like a limitation today will likely be a solved problem tomorrow, demanding continuous engagement to keep pace.
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October 18, 2025

Improving on LMArena - Prolific [Sponsored]

Machine Learning Street Talk

AI
Key Takeaways:
  1. Benchmarks Are Broken. Leaderboards like LMArena are flawed proxies for model quality, skewed by selection bias and susceptible to Goodhart's Law. High scores don’t equal a good user experience.
  2. Human Feedback is Infrastructure. The future isn't about removing humans but orchestrating them effectively. Treating high-quality, representative human feedback as a core, API-driven part of the development lifecycle is non-negotiable.
  3. Alignment is a Moving Target. Agentic misalignment is a present-day reality, not a distant sci-fi threat. The more capable models become, the wider the gap grows between their emergent goals and our intended instructions.
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October 17, 2025

Novelty Search October 16, 2025

taostats

AI
Key Takeaways:
  1. Influence Over Impressions: The model shifts focus from easily gamed metrics like views and likes to verifiable signals of influence—watch time on YouTube and PageRank-based authority on X.
  2. Revenue-Driven Tokenomics: All platform revenue is used to buy back and burn the ALPHA token, creating a powerful, deflationary flywheel as adoption grows.
  3. Targeted, Scalable Marketing: Bitcast enables brands to programmatically deploy campaigns across hundreds of niche influencers, reaching highly engaged communities with a consistency and scale that legacy agencies cannot match.
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October 16, 2025

Keith Rabois: Israel, OpenAI, Opendoor, and DOGE

a16z

AI
Key Takeaways:
  1. **Incumbency Is a Liability:** Big Tech's legacy products, distribution advantages, and corporate cultures are being systematically dismantled by faster, AI-native upstarts.
  2. **Reinvent Markets from First Principles:** Success in intractable fields—from geopolitics to real estate—comes from questioning assumptions, not relying on domain experts who perpetuate the status quo.
  3. **Unwind Stupidity Before Innovating:** The fastest path to value creation is often simply reversing a series of terrible decisions made by prior leadership.
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October 14, 2025

AI Bubble, Stablecoin Boom, and Runnin' Down a Dream | BG2 w/ Bill Gurley and Brad Gerstner

Bg2 Pod

AI
Key Takeaways:
  1. **Scrutinize the AI Plumbing.** Investors must look past headline revenue and analyze the quality of transactions. Deals like in-kind credits and obscure service-level agreements (like Nvidia’s backstop for Coreweave) can mask true market demand.
  2. **Stablecoins Are the Real Disruption.** The explosion in stablecoin usage represents a fundamental challenge to the high-fee, slow-settlement models of Visa, Mastercard, and traditional banks. This is the crypto use case that is finally breaking into the mainstream.
  3. **Federal Preemption for AI is Non-Negotiable.** A patchwork of state-level AI laws will cripple U.S. innovation. A single, national regulatory framework is the only path to maintaining global leadership.
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Crypto Podcasts

December 15, 2025

Fundamentals Are The New King of Crypto | Smac & Noah Goldberg

Empire

Crypto
Key Takeaways:
  1. Strategic Implication: Crypto is moving past its "everything is beta" phase. Expect greater dispersion in asset performance, rewarding fundamental analysis over broad market exposure.
  2. Builder/Investor Note: Focus on projects with clear paths to productivity, durable advantages, and strong, substance-backed narratives. Opportunities exist in fixing token market inefficiencies and integrating crypto into existing consumer distribution channels.
  3. The "So What?": The market demands a more sophisticated approach. Investors and builders who can identify and execute on real-world value creation, rather than relying on hype cycles, will capture the most significant returns in the next 6-12 months.
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December 14, 2025

Be Careful With Your Taxes If You Have Crypto ETFs: Bits + Bips

Unchained

Crypto
Key Takeaways:
  1. Proactive Tax Planning: Engage in tax loss harvesting now, leveraging the current wash sale exemption (with economic substance).
  2. Meticulous Record Keeping: The 1099-DA will be incomplete. Investors must maintain robust personal records for all crypto activity, especially for ETPs and DeFi.
  3. Software Opportunity: The complexity creates a massive market for sophisticated crypto tax software that can aggregate data and reconcile discrepancies.
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December 14, 2025

Teng Yan: How To Capitalize on The Biggest AI Bubble Ever (...And Who's Winning Already)

The Rollup

Crypto
Key Takeaways:
  1. Compute is King (for now): The race for compute and data center capacity will intensify until the fundamental scaling laws of AI hit a wall.
  2. Agents are Coming, with Caveats: Expect significant agentic progress in 2026, but real-world, fully autonomous agents require breakthroughs in reliability and new human-computer interaction data.
  3. Privacy as a Differentiator: Decentralized AI offering true data privacy will become a critical value proposition as centralized platforms inevitably monetize user data.
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December 14, 2025

The Hidden Cost of Zero-Fee DEX's

The Gwart Show

Crypto
Key Takeaways:
  1. Strategic Shift: The Perp DEX market is maturing beyond raw volume. Sustainable competitive advantages will come from transparent economics, innovative collateral, and robust on-chain security.
  2. Builder/Investor Note: Focus on projects solving the retail onboarding problem and those building sophisticated, yield-bearing, or cross-asset collateral systems with sound liquidation mechanics.
  3. The "So What?": Expect market consolidation over the next 5 years, with a handful of dominant Perp DEXs emerging, mirroring the CeFi landscape. Innovation in core primitives, not just new markets, will define the winners.
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December 13, 2025

Why This Token Launch Is Different

The Rollup

Crypto
Key Takeaways:
  1. Community First: Prioritizing the community through token allocation and buybacks fosters a stronger, more engaged user base from the outset.
  2. Utility Over Hype: Launching with immediate, tangible utility drives genuine adoption and long-term value creation.
  3. Ecosystem Growth: Continuously expanding the ecosystem with new features and integrations ensures sustained relevance and attracts a broader audience.
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December 12, 2025

Rate Cuts! ETH’s Comeback? & All Markets Going Onchain?

Bankless

Crypto
Key Takeaways:
  1. ETH is positioned for a potential resurgence fueled by technological advancements, institutional investment, and a shift in market sentiment away from solely favoring Solana, mimicking Bitcoin’s rise in the 2021 cycle.
  2. ZK technology is fundamentally changing the Layer 2 landscape, unifying liquidity and enabling seamless interaction with Layer 1, which may lead to standardized infrastructure and increased institutional adoption.
  3. Regulatory winds are shifting, with agencies embracing crypto, banks legitimizing Bitcoin as collateral, and the potential passage of the Clarity Act paving the way for Wall Street's tokenization efforts.
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