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AI Podcasts

January 18, 2026

Why Every Brain Metaphor in History Has Been Wrong [SPECIAL EDITION]

Machine Learning Street Talk

AI
Key Takeaways:
  1. The Strategic Pivot: The transition from "Understanding-First" science to "Prediction-First" engineering. We are building artifacts that work perfectly but remain theoretically opaque.
  2. The Tactical Edge: Audit your AI stack for "Leaky Abstractions." Don't assume a model's reasoning capabilities in one domain will hold when the underlying causal structure changes.
  3. AGI isn't just an engineering milestone; it's a philosophical wager. If the brain isn't a computer, we are building a very powerful helicopter, not a synthetic human.
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January 18, 2026

Why Every Brain Metaphor in History Has Been Wrong [SPECIAL EDITION]

Machine Learning Street Talk

AI
Key Takeaways:
  1. The pivot from "Understanding-First" science to "Prediction-First" engineering creates massive technical liability in our models.
  2. Audit your AI implementations for "Leaky Abstractions" where the model fails to account for physical edge cases.
  3. High-performance automation is not the same as sentient reasoning. Builders who recognize this distinction will avoid the cultural illusion of inevitable AGI.
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January 17, 2026

Brex’s AI Hail Mary — With CTO James Reggio

Latent Space

AI
Key Takeaways:
  1. The transition from deterministic software to agentic networks. Companies are moving from rigid workflows to fluid systems that plan and execute autonomously.
  2. Build an internal LLM gateway early. Centralizing model routing and cost monitoring allows you to swap providers as the model horse race changes without refactoring your product.
  3. AI is not just a feature but a fundamental restructuring of the corporate cost center. Efficiency gains allow a static headcount of 300 engineers to support a business growing 5x.
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January 14, 2026

Identity for AI Agents - Patrick Riley & Carlos Galan, Auth0

AI Engineer

AI
Key Takeaways:
  1. The transition from interactive chat to autonomous "task runners" requires a shift from session-based identity to delegated, long-term authorization.
  2. Implement the Token Vault pattern to decouple your agent logic from the mess of OAuth token refreshing.
  3. In the next year, the "Agentic Web" will live or die by trust. If you cannot prove an agent is authorized to act, it is just a fancy toy.
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January 15, 2026

AI and the Future of Warfare with US Under Secretary of War Emil Michael

No Priors: AI, Machine Learning, Tech, & Startups

AI
Key Takeaways:
  1. The Macro Shift: The Great Re-Shoring. National security now depends on domestic production of critical minerals and semiconductors.
  2. The Tactical Edge: Build for Scale. Prioritize manufacturing competence over pure software features to win government contracts.
  3. The Bottom Line: The defense industrial base is being rebuilt from the ground up. The next decade belongs to the builders who can merge Silicon Valley speed with the Pentagon's scale.
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January 15, 2026

Ben & Marc: Why Everything Is About to Get 10x Bigger

a16z

AI
Key Takeaways:
  1. The transition from software eating the world to AI reinventing the computer means every existing market cap is a floor.
  2. Prioritize the non-fungible creator by providing monetization tools that bypass legacy gatekeepers.
  3. We are entering a period of asymmetric payoffs where the art of picking original thinkers matters more than historical data.
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January 13, 2026

Paul Rosolie: Uncontacted Tribes in the Amazon Jungle | Lex Fridman Podcast #489

Lex Fridman

AI
Key Takeaways:
  1. The Macro Trend: Biological Sovereignty. As global systems destabilize, the Amazon remains the most critical piece of biological infrastructure on the planet.
  2. The Tactical Edge: Support Jungle Keepers. Direct capital to organizations that convert loggers into rangers to secure land concessions.
  3. The Amazon is a finite asset under active siege. Protecting it requires a blend of primitive survival skills and high-tech surveillance over the next 18 months.
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January 12, 2026

Jensen Huang says robots will have human capabilities this year! The Robots at CES Had.. Other Plans

Turing Post

AI
Key Takeaways:
  1. The Macro Pivot: As generative AI masters simulation, the physical world becomes a high-fidelity playground for software.
  2. The Tactical Edge: Invest in the "brain" layer rather than the "limb" layer. Software that can generalize across different hardware forms will capture the most value.
  3. The next decade belongs to embodied AI that reasons in real time. If you are waiting for the hardware to look perfect before paying attention, you will miss the moment the software takes over the physical world.
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January 12, 2026

Your MCP Server is Bad (and you should feel bad) - Jeremiah Lowin, Prefect

AI Engineer

AI
Key Takeaways:
  1. The Macro Pivot: Context as Product. We are moving from raw data transport to opinionated context delivery.
  2. The Tactical Edge: Prune your endpoints. Remove any tool that requires more than one step to achieve a business result.
  3. The Bottom Line: The winners of the agentic era will be those who build the best Agentic Interface Guidelines.
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Crypto Podcasts

January 13, 2026

How Claude Code is Changing the World with Nick Emmons

The Rollup

Crypto
Key Takeaways:
  1. The transition from human-centric interfaces to agent-first protocols. As agents become the primary users, the internet will be rebuilt around machine-readable data and crypto-native payment rails.
  2. Integrate Model Context Protocol (MCP) servers into your workflow immediately. Use parallel Claude instances to act as both programmer and reviewer to bypass context window degradation.
  3. Software is no longer a product: it is a utility. Over the next year, the winners will be those who control the data graphs and the distribution channels, not the ones writing the code.
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January 12, 2026

Claude Opus 4.5’s Breakout Moment & Investing in 2026 with Qiao Wang

Empire

Crypto
Key Takeaways:
  1. The Macro Pivot: Proprietary data and enterprise switching costs are the only walls left standing as AI commoditizes the act of writing code.
  2. The Tactical Edge: Build internal tools using natural language agents to automate specific, low-volume workflows that third-party vendors ignore.
  3. The Bottom Line: The billion-dollar company with a single employee is no longer a fantasy; it is a mathematical certainty for those who master the prompt over the next twelve months.
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January 13, 2026

How Claude Code is Changing the World with Nick Emmons

The Rollup

Crypto
Key Takeaways:
  1. The migration from human-centric interfaces to agent-first protocols where software is a temporary utility rather than a permanent product.
  2. Use Git and MCP servers to give your agents a persistent memory and toolset, allowing them to work autonomously through complex loops.
  3. Software is no longer the prize; it is the commodity. Your value in the next year depends on how well you direct the agents that build it.
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January 12, 2026

HIP-3 Market Design and Felix’s Role | Charlie, Felix Protocol

0xResearch

Crypto
Key Takeaways:
  1. The Macro Strategic Pivot: Vertical Consolidation. Protocols are moving away from modularity toward integrated stacks to capture maximum fee revenue.
  2. The Tactical Edge: Monitor BLP Rates. Watch the spread between Felix and Hyperliquid’s native lending rates. Capital will migrate to the platform offering the lowest borrow cost for margin trading.
  3. The Bottom Line: Hyperliquid is winning by becoming a DeFi Super App rather than just a perp engine. Its success over the next year depends on its ability to manage UI fragmentation while keeping all revenue inside the Hype ecosystem.
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January 12, 2026

Is Canton a Real Blockchain? | Canton Founder Yuval Rooz

Bankless

Crypto
Key Takeaways:
  1. The Macro Transition: We are seeing a split between "Pure Crypto" for sovereignty and "Institutional Rails" for global capital markets.
  2. The Tactical Edge: Monitor Broadridge volume to gauge the actual velocity of institutional on-chain adoption.
  3. The Bottom Line: The next decade is not about crypto replacing banks. It is about banks adopting crypto's efficiency while keeping their legal moats.
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January 12, 2026

Who Actually Owns the Aave Brand -- the DAO or Labs? Uneasy Money

Unchained

Crypto
Key Takeaways:
  1. The "Fat App" thesis is evolving into the "Sovereign Brand" thesis where the front-end is the ultimate moat.
  2. Audit your protocol's meatspace dependencies—domains, trademarks, and front-ends—before they become points of failure.
  3. Decentralization isn't just about smart contracts; it is about ensuring the front door to your protocol cannot be locked by a single executive.
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