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AI Podcasts

December 17, 2025

Rethinking Pre-Training for Agentic AI [Aakanksha Chowdhery] - 759

The TWIML AI Podcast with Sam Charrington

AI
Key Takeaways:
  1. Pre-Training is the New Frontier: The next leap in AI capabilities, particularly for agentic systems, will come from fundamental advancements in pre-training, not just post-training tweaks.
  2. Builders & Investors: Focus on teams rethinking loss objectives, curating high-quality reasoning data, and developing dynamic benchmarks for agentic capabilities. Be wary of "agentic" claims that lack foundational pre-training innovation.
  3. The "So What?": Over the next 6-12 months, expect a push for new benchmarks and data strategies that explicitly train models for multi-step planning, long-form reasoning, and error recovery, moving beyond simple next-token prediction.
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December 16, 2025

What We Learned Deploying AI within Bloomberg’s Engineering Organization – Lei Zhang, Bloomberg

AI Engineer

AI
Key Takeaways:
  1. Strategic Implication: AI fundamentally changes the economics of software development. Organizations must re-evaluate what constitutes "high-quality" engineering and adapt their processes.
  2. Builder/Investor Note: Prioritize platforms that provide guardrails and guidance for AI tool usage, focusing on deterministic verification and robust testing. Uncontrolled AI deployment risks technical debt.
  3. The "So What?": The next 6-12 months will see a bifurcation: companies that strategically integrate AI into their engineering culture and platforms will gain significant efficiency, while those that don't will struggle with quality and adoption.
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December 16, 2025

Your Support Team Should Ship Code – Lisa Orr, Zapier

AI Engineer

AI
Key Takeaways:
  1. Workflow Automation is the New Frontier: The real value of AI in developer tools comes from orchestrating entire workflows, not just individual point solutions.
  2. Embed for Adoption: Tools must integrate seamlessly into existing workflows and IDEs (like Cursor) to achieve high usage.
  3. Support as a Code-Shipping Powerhouse: Empowering non-traditional roles with AI-driven code generation leverages their unique, real-time context, creating significant operational leverage.
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December 17, 2025

Code World Model: Building World Models for Computation – Jacob Kahn, FAIR Meta

AI Engineer

AI
Key Takeaways:
  1. Semantic Shift: The future of AI in code moves from text generation to deep semantic understanding and execution simulation.
  2. Builder Opportunity: Develop next-generation debugging tools and code agents that leverage internal simulation for faster, more efficient development cycles.
  3. Investor Focus: Prioritize models and platforms that demonstrate explicit execution modeling, as this capability will redefine software development and create new market leaders.
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December 17, 2025

AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs

AI Engineer

AI
Key Takeaways:
  1. Infrastructure Shift: AI-driven kernel optimization addresses a critical bottleneck in scaling AI compute, enabling more efficient use of diverse hardware.
  2. Builder/Investor Note: Focus on solutions with robust, hardware-verified performance metrics and a clear human-in-the-loop strategy. AI is a powerful tool for automating optimization, not a magic bullet for novel algorithmic breakthroughs.
  3. The "So What?": This technology frees expert engineers from tedious optimization, allowing them to focus on higher-level research and truly innovative algorithmic design, accelerating the pace of AI development in the next 6-12 months.
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December 16, 2025

Finding The 1% of Stocks That Matter | Henry Ellenbogen Interview

Invest Like The Best

AI
Key Takeaways:
  1. Strategic Implication: The era of "free money" inflated the number of perceived compounders; a return to positive real rates demands a sharper focus on businesses demonstrating genuine financial discipline and competitive advantage.
  2. Builder/Investor Note: Seek out "Act 2" entrepreneurs and companies that can leverage AI to transform existing physical or IP-based advantages, not just create new AI products. Be prepared to buy more when market sentiment turns negative on strong businesses.
  3. The "So What?": The next 6-12 months will differentiate companies that merely adopt AI from those that strategically integrate it to build durable, uncatchable cost and distribution advantages.
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December 17, 2025

“How We Can Eliminate Crime” | Ben Horowitz and Garrett Langley

a16z

AI
Key Takeaways:
  1. The Future of Policing is Intelligent: Integrating AI, drones, and smart cameras creates a precise, accountable, and safer policing model for both officers and communities.
  2. Invest in the "How": Builders and investors should focus on technologies that enhance certainty of capture, streamline judicial processes, and support public-private partnerships to modernize urban safety infrastructure.
  3. Safety Fuels Mobility: Eliminating crime is not just about law enforcement; it's about restoring the fundamental safety required for economic mobility and a functional society.
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December 18, 2025

Two Futures | Runtime 2025

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next decade's value will accrue to those building foundational AI infrastructure and the "invisible layers" that connect intelligent systems.
  2. Builder/Investor Note: Focus capital and talent on core AI models, specialized domain intelligence, and the underlying computational fabric. Superficial applications risk rapid commoditization.
  3. The So What?: This is the defining period for the architecture of global intelligence. Participation now determines future influence and relevance.
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December 16, 2025

⚡️Jailbreaking AGI: Pliny the Liberator & John V on Red Teaming, BT6, and the Future of AI Security

Latent Space

AI
Key Takeaways:
  1. Strategic Shift: AI security must move beyond superficial guardrails to a full-stack, offensive red-teaming approach that accounts for the expanding attack surface of AI agents and their tool access.
  2. Builder/Investor Note: Builders should prioritize integrating offensive security early in development. Investors should be wary of "security theater" and favor solutions that embrace open-source collaboration and address the entire AI application stack.
  3. The "So What?": The accelerating pace of AI development means static security solutions will quickly become obsolete. Proactive, community-driven, and full-stack security research is essential for navigating the next 6-12 months of AI evolution.
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Crypto Podcasts

June 9, 2025

Is Joe Lubin the Michael Saylor of Ethereum?

Bankless

Crypto
Key Takeaways:
  1. Regulatory Renaissance: The SEC's stance has softened, creating a more favorable U.S. environment for crypto; Ether's non-security status (for the scope of the past investigation) is a major win.
  2. Ether as a Productive Treasury Asset: ESBET's strategy of acquiring and actively yielding Ether could set a new standard for corporate treasuries, showcasing Ether's utility beyond just holding.
  3. The "Trust Commodity" Narrative: Expect a strong push to frame Ether's value around its ability to provide programmable trust and facilitate economic activity, with Lubin championing this.
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June 6, 2025

Could Crypto Treasury Companies Create Systemic Risk for the Industry?

Unchained

Crypto
Key Takeaways:
  1. High Premiums are a Red Flag: The massive premiums (some at 80x NAV) on many new crypto treasury stocks are likely unsustainable and warrant extreme investor caution.
  2. Collateralization is the Catalyst: The primary systemic risk emerges if these shares become widely accepted as collateral, creating a leveraged ecosystem vulnerable to market shocks.
  3. History as a Guide: The industry must heed the lessons from GBTC's collapse to prevent irresponsible risk-taking and a potential repeat of cascading failures.
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June 6, 2025

0xResearch | Friday, June 6th

0xResearch

Crypto
Key Takeaways:
  1. Fiscal Reality Bites: Government spending, not just Fed moves, dictates the macro game; hedge accordingly.
  2. Structure Matters, Massively: Demand for "pure play" crypto assets is immense; projects clarifying token value accrual (a la Morpho) will win.
  3. Show, Don't Just Tell: For L1s and protocols, delivering tangible results and clear revenue paths to token holders trumps theoretical brilliance.
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June 6, 2025

PumpFun’s Impact on Solana, Circle’s IPO, and Elon and Trump’s Feud | Roundup

Bell Curve

Crypto
Key Takeaways:
  1. PumpFun's Token Looms Large: With its massive user base and revenue, PumpFun's upcoming token is a critical event for Solana and the broader memecoin market, offering a direct investment into crypto's consumer wave.
  2. IPO Window is Open: Circle's successful IPO signals renewed investor interest in publicly traded crypto companies, potentially paving the way for more listings and providing liquidity events for equity holders.
  3. Regulatory Clarity is King: The future of crypto innovation, from token launches to organizational structures, hinges on clear market structure legislation to move beyond current cumbersome models.
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June 6, 2025

Don’t Midcurve Circle and PumpFun | Weekly Roundup

Empire

Crypto
Key Takeaways:
  1. Don't Midcurve Success: Circle’s IPO triumph, despite online skepticism, shows that strong fundamentals and clear value propositions (like stablecoin infrastructure) attract serious capital.
  2. Ambition Attracts Capital (and Scrutiny): Pump.fun's massive raise, while controversial, signals a drive to leverage its huge user base for something much bigger than memecoins. Profitability plus vision equals investor interest.
  3. IPO Pipeline Primed: Circle’s success is a catalyst, likely opening the IPO floodgates for other mature crypto companies sooner than anticipated.
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June 6, 2025

How Will Pump Fun's Token Impact Solana? | Weekly Roundup

Lightspeed

Crypto
Key Takeaways:
  1. Cash is King (Again): Pump Fun's $1B target underscores a potential shift back to ICOs for well-capitalized projects, offering a war chest for aggressive expansion, M&A, and de-risking beyond what current revenues allow.
  2. Distribution is Destiny: Pump Fun's long-term viability hinges on owning its front-end and user discovery to avoid disintermediation, making moves into wallets or even exchanges critical.
  3. Solana Symbiosis Likely: Despite L1/L2 speculation, Pump Fun’s incentives align more with growing the existing memecoin market on Solana rather than fragmenting its user base by launching a new chain, especially given Solana's ongoing performance enhancements.
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