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AI Podcasts

May 30, 2025

SN17 - 404GEN :: Decentralized AI generated 3D assets

Opentensor Foundation

AI
Key Takeaways:
  1. Unlocking Creative Potential: 404GEN radically lowers barriers to 3D content creation, enabling faster iteration and new forms of interactive media previously unfeasible for smaller teams or individuals.
  2. Gaussian Splats are Ascendant: This representation is emerging as a powerful alternative for 3D AI, and 404GEN is at the forefront of its practical application and tooling.
  3. BitTensor's Competitive Edge Shines: The subnet's rapid quality improvement and the innovative ELO validation system highlight BitTensor's power to incentivize and coordinate decentralized intelligence towards state-of-the-art results.
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May 30, 2025

Hey Tech, Come to Healthcare

a16z

AI
Key Takeaways:
  1. **Build for Behavior Change:** The biggest wins will come from engaging consumers and enabling sustainable health behaviors, an area where tech excels.
  2. **AI is the Leapfrog:** Healthcare can jump directly to AI-driven solutions, bypassing clunky legacy software, especially for service-oriented tasks.
  3. **The Trillion-Dollar Prize is Real:** Whether through full-stack "payvider" models or horizontal platforms, the path to becoming the world's largest company runs through transforming the consumer healthcare experience.
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May 29, 2025

Building a DePIN-powered Shazam for Media with Rumi | Niko Cunningham and Mateusz Poreda

Proof of Coverage Media

AI
Key Takeaways:
  1. **Decentralized Analytics:** Rumi’s DePIN model democratizes media intelligence, offering far richer and more granular data than traditional players like Nielsen.
  2. **Context is King:** The "Shazam for media" capability will fuel a new generation of AI agents and interactive experiences, making media deeply engaging.
  3. **Investor Signal:** The $5M pre-seed (EV3, A16Z CSX) and early traction with industry players like Tivision validate Rumi's approach and market potential.
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May 29, 2025

Beyond Leaderboards: LMArena’s Mission to Make AI Reliable

a16z

AI
Key Takeaways:
  1. Reliability Demands Real-Time, Human-Centric Testing: Static benchmarks are dead. AI reliability for complex tasks requires continuous evaluation based on diverse, subjective human preferences in real-world scenarios.
  2. Crowd-Sourced Evaluation Outperforms Insular Expertise: The "wisdom of the crowd," as captured by LMArena, provides a more robust and representative measure of AI performance than siloed expert opinions, preventing narrow value-encoding.
  3. Personalized Evaluation is the Next Frontier: Technologies like "Prompt to Leaderboard" show the potential for highly granular, cost-effective, and personalized AI model selection, maximizing utility for individual users and specific tasks.
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May 28, 2025

Rick Rubin: Vibe Coding is the Punk Rock of Software

a16z

AI
Key Takeaways:
  1. Embrace AI as a Co-Creator: Leverage AI to democratize creation and rapidly iterate, but remember the unique human element—your distinct point of view and intuition—is irreplaceable.
  2. Authenticity Over Algorithm: Whether you're an artist or an entrepreneur, genuine connection comes from unwavering commitment to your core vision, not by chasing fleeting trends or assumed audience desires.
  3. Question Everything, Especially "Answers": Cultivate a mindset of curiosity and critical thinking. AI can provide answers, but true insight comes from deeply engaging with questions and understanding that knowledge is ever-evolving.
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May 27, 2025

7 More Healthy Years: What We Can Learn from Super Agers

a16z

AI
Key Takeaways:
  1. Embrace AI-Powered Prevention: AI's capacity to synthesize vast health data will redefine personalized risk assessment and early intervention, moving us beyond one-size-fits-all healthcare.
  2. Target the "Big Three" Early: Focus on preventing cancer, cardiovascular disease, and neurodegenerative conditions by leveraging their long incubation periods for proactive interventions.
  3. Leverage New Therapeutic Frontiers: Groundbreaking drug classes like GLP-1s and rapid advancements in immunotherapy offer unprecedented tools to combat and, crucially, prevent major diseases.
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May 27, 2025

TAOFU's Mikel & Mitch: Enabling Capital Formation for Subnets on Bittensors $10B+ Network

Delphi Digital

AI
Key Takeaways:
  1. Democratized Subnet Funding: TAOFU’s SNS model allows subnet creators to raise capital without diluting their core emission-earning potential, fostering more shots on goal for AI innovation on Bittensor.
  2. Investor Access & Liquidity: For investors, TAOFU provides a clear mechanism (SNS tokens and an integrated DEX) to invest in early-stage Bittensor subnets and gain liquidity, previously a closed-off and opaque process.
  3. Curated Quality: TAOFU’s permissioned approach and focus on sustainable value capture (with plans for a curator model) aim to filter for high-quality projects, protecting investors while nurturing promising AI ventures within Bittensor.
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May 26, 2025

Has AI Revived the DePIN Sector? | Dmitriy Berenzon

0xResearch

AI
Key Takeaways:
  1. AI is DePIN's Demand Catalyst: The need for affordable AI compute is breathing new life and tangible demand into decentralized infrastructure.
  2. Value Accrual & Revenue are King: For DePIN tokens to thrive in liquid markets, clear mechanisms for value flow-through from opco revenue to the token are non-negotiable; "ARR is the new TVL."
  3. Distribution Trumps Decentralization (for now): Crypto-native solutions, especially in payments, must crack the distribution code or risk being outmaneuvered by Web2 incumbents leveraging their massive user bases.
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May 26, 2025

Chatbot platforms might replace social media

Machine Learning Street Talk

AI
Key Takeaways:
  1. AI Companionship is Exploding: Millions are already deeply engaged with AI for emotional connection, and this is just the beginning as technology like GPT-4o normalizes it.
  2. Lean Engineering Can Win: Chai's success with a tiny, hyper-talented team and innovative techniques like model blending proves that massive VC-backed operations aren't the only path to scale in AI.
  3. The Next Social Platform Might Be AI: As AI offers more active, personalized, and consequence-free social interaction, it could very well become the dominant way people connect, potentially supplanting traditional social media.
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Crypto Podcasts

October 10, 2025

Why This Early Solana Investor Is Still All In | Viktor Fischer

Lightspeed

Crypto
Key Takeaways:
  1. **The L1 War Is Won.** Don't bet on new L1s. The network effects, developer mindshare, and ecosystem infrastructure of chains like Solana and Base have created an insurmountable moat.
  2. **DATs Are the Trojan Horse for TradFi.** Digital Asset Treasury companies are the key to unlocking Wall Street capital. Expect Solana DATs to drive a massive TVL re-rating in 2026 as their superior yield generation becomes undeniable.
  3. **SOL to $2,000 Is the Base Case.** This price target isn't based on meme-fueled hype, but on a model where Solana captures just 10% of the projected multi-trillion-dollar tokenized asset market by 2030.
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October 9, 2025

Andre Cronje: How the SEC Tried to Shut Me Down

The DCo Podcast

Crypto
Key Takeaways:
  1. Regulation by Exhaustion: The SEC's primary weapon was not legal action but a relentless process designed to drain builders' time, energy, and will to continue.
  2. The Target Is Always Moving: Regulators will continuously shift their focus—from token to revenue to the product itself—until they find a viable angle of attack.
  3. Innovation Was the Real Target: This "shotgun approach" against hundreds of projects was a de facto industry crackdown that successfully chased many legitimate builders away, achieving a policy goal without ever going to court.
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October 8, 2025

The BTC/Gold Ratio Is Screaming "Higher"

1000x Podcast

Crypto
Key Takeaways:
  1. Stop Pricing in Fiat: The BTC/Gold ratio is the clearest signal of Bitcoin’s fundamental adoption, stripping away the distortion of dollar debasement.
  2. Mean Reversion Points to $150k+: The established BTC/Gold trend channel since 2023 is screaming higher. A simple return to the channel’s midpoint targets a $150k–$160k Bitcoin price by year-end.
  3. Gold's Rally is Bitcoin's Tailwind: Gold’s new role as a de-dollarization hedge for nations and the subsequent portfolio rebalancing from gold profits into BTC create powerful dual-demand drivers for Bitcoin.
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October 8, 2025

Steady Lads Live From TOKEN2049 in Singapore! w/ Dim Selk

Steady Lads Podcast

Crypto
Key Takeaways:
  1. Profit, Don't HODL. The current market is a trader’s paradise, not an investor’s dream. The strategy is to ride the seasonal Q4 pump and exit by January, refusing to get caught in another brutal bear cycle.
  2. Fade the Old, Farm the New. Capital is mercenary, flowing from established tokens to the next hot airdrop farm or launch. The relentless hunt for volatility means older coins are treated as exit liquidity for the next shiny object.
  3. Unlocks Are the Silent Killer. Before investing, map out the token unlock schedule. Even fundamentally sound projects with strong revenue face a massive gravitational pull on their price from insider and team unlocks.
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September 17, 2025

FinTech Meets Crypto: The Future of Global Payments

Bankless

Crypto
Key Takeaways:
  1. **Stablecoins Are Rebranding Crypto.** The FinTech industry is adopting stablecoin technology not as a niche crypto asset, but as the foundational layer for "FinTech 3.0," poised to overhaul global payments.
  2. **The EVM Is The New COBOL.** Specialized payments chains are standardizing the EVM as the backend for modern finance, creating high-throughput, compliant on-ramps that will bring trillions in TradFi volume on-chain.
  3. **Payments Are Just The Beginning.** Once the world rebuilds its payments infrastructure on stablecoins, the floodgates will open for the complete tokenization of all financial assets, forever blurring the line between crypto and finance.
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September 16, 2025

Collector Crypt: Onchain Capital Markets On Solana | Tuomas Holmberg

Lightspeed

Crypto
Key Takeaways:
  1. Onchain Rails Create New Economies. By digitizing physical assets on high-performance chains like Solana, you eliminate friction around custody, settlement, and global access, unlocking novel business models like the Gotcha Machine.
  2. Real-World Logistics Are the Ultimate Moat. While anyone can build a smart contract, Collector Crypt’s defensibility comes from its physical supply chain—dealer relationships and automated acquisition tools that secure inventory below market price.
  3. Novel Oracles Unlock the Next Wave of DeFi. The future of onchain finance depends on reliably pricing illiquid, real-world assets. Developing proprietary oracles, like Collector Crypt’s, is the first step to building DeFi for everything.
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