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AI Podcasts

December 17, 2025

Rethinking Pre-Training for Agentic AI [Aakanksha Chowdhery] - 759

The TWIML AI Podcast with Sam Charrington

AI
Key Takeaways:
  1. Pre-Training is the New Frontier: The next leap in AI capabilities, particularly for agentic systems, will come from fundamental advancements in pre-training, not just post-training tweaks.
  2. Builders & Investors: Focus on teams rethinking loss objectives, curating high-quality reasoning data, and developing dynamic benchmarks for agentic capabilities. Be wary of "agentic" claims that lack foundational pre-training innovation.
  3. The "So What?": Over the next 6-12 months, expect a push for new benchmarks and data strategies that explicitly train models for multi-step planning, long-form reasoning, and error recovery, moving beyond simple next-token prediction.
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December 16, 2025

What We Learned Deploying AI within Bloomberg’s Engineering Organization – Lei Zhang, Bloomberg

AI Engineer

AI
Key Takeaways:
  1. Strategic Implication: AI fundamentally changes the economics of software development. Organizations must re-evaluate what constitutes "high-quality" engineering and adapt their processes.
  2. Builder/Investor Note: Prioritize platforms that provide guardrails and guidance for AI tool usage, focusing on deterministic verification and robust testing. Uncontrolled AI deployment risks technical debt.
  3. The "So What?": The next 6-12 months will see a bifurcation: companies that strategically integrate AI into their engineering culture and platforms will gain significant efficiency, while those that don't will struggle with quality and adoption.
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December 16, 2025

Your Support Team Should Ship Code – Lisa Orr, Zapier

AI Engineer

AI
Key Takeaways:
  1. Workflow Automation is the New Frontier: The real value of AI in developer tools comes from orchestrating entire workflows, not just individual point solutions.
  2. Embed for Adoption: Tools must integrate seamlessly into existing workflows and IDEs (like Cursor) to achieve high usage.
  3. Support as a Code-Shipping Powerhouse: Empowering non-traditional roles with AI-driven code generation leverages their unique, real-time context, creating significant operational leverage.
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December 17, 2025

Code World Model: Building World Models for Computation – Jacob Kahn, FAIR Meta

AI Engineer

AI
Key Takeaways:
  1. Semantic Shift: The future of AI in code moves from text generation to deep semantic understanding and execution simulation.
  2. Builder Opportunity: Develop next-generation debugging tools and code agents that leverage internal simulation for faster, more efficient development cycles.
  3. Investor Focus: Prioritize models and platforms that demonstrate explicit execution modeling, as this capability will redefine software development and create new market leaders.
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December 17, 2025

AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs

AI Engineer

AI
Key Takeaways:
  1. Infrastructure Shift: AI-driven kernel optimization addresses a critical bottleneck in scaling AI compute, enabling more efficient use of diverse hardware.
  2. Builder/Investor Note: Focus on solutions with robust, hardware-verified performance metrics and a clear human-in-the-loop strategy. AI is a powerful tool for automating optimization, not a magic bullet for novel algorithmic breakthroughs.
  3. The "So What?": This technology frees expert engineers from tedious optimization, allowing them to focus on higher-level research and truly innovative algorithmic design, accelerating the pace of AI development in the next 6-12 months.
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December 16, 2025

Finding The 1% of Stocks That Matter | Henry Ellenbogen Interview

Invest Like The Best

AI
Key Takeaways:
  1. Strategic Implication: The era of "free money" inflated the number of perceived compounders; a return to positive real rates demands a sharper focus on businesses demonstrating genuine financial discipline and competitive advantage.
  2. Builder/Investor Note: Seek out "Act 2" entrepreneurs and companies that can leverage AI to transform existing physical or IP-based advantages, not just create new AI products. Be prepared to buy more when market sentiment turns negative on strong businesses.
  3. The "So What?": The next 6-12 months will differentiate companies that merely adopt AI from those that strategically integrate it to build durable, uncatchable cost and distribution advantages.
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December 17, 2025

“How We Can Eliminate Crime” | Ben Horowitz and Garrett Langley

a16z

AI
Key Takeaways:
  1. The Future of Policing is Intelligent: Integrating AI, drones, and smart cameras creates a precise, accountable, and safer policing model for both officers and communities.
  2. Invest in the "How": Builders and investors should focus on technologies that enhance certainty of capture, streamline judicial processes, and support public-private partnerships to modernize urban safety infrastructure.
  3. Safety Fuels Mobility: Eliminating crime is not just about law enforcement; it's about restoring the fundamental safety required for economic mobility and a functional society.
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December 18, 2025

Two Futures | Runtime 2025

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next decade's value will accrue to those building foundational AI infrastructure and the "invisible layers" that connect intelligent systems.
  2. Builder/Investor Note: Focus capital and talent on core AI models, specialized domain intelligence, and the underlying computational fabric. Superficial applications risk rapid commoditization.
  3. The So What?: This is the defining period for the architecture of global intelligence. Participation now determines future influence and relevance.
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December 16, 2025

⚡️Jailbreaking AGI: Pliny the Liberator & John V on Red Teaming, BT6, and the Future of AI Security

Latent Space

AI
Key Takeaways:
  1. Strategic Shift: AI security must move beyond superficial guardrails to a full-stack, offensive red-teaming approach that accounts for the expanding attack surface of AI agents and their tool access.
  2. Builder/Investor Note: Builders should prioritize integrating offensive security early in development. Investors should be wary of "security theater" and favor solutions that embrace open-source collaboration and address the entire AI application stack.
  3. The "So What?": The accelerating pace of AI development means static security solutions will quickly become obsolete. Proactive, community-driven, and full-stack security research is essential for navigating the next 6-12 months of AI evolution.
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Crypto Podcasts

June 12, 2025

The Last Mile Problem For Stablecoins | Analyst Round Table

0xResearch

Crypto
Key Takeaways:
  1. **Solve Real Friction:** The "last-mile" challenge—seamlessly converting stablecoins to local cash in emerging markets—remains the critical bottleneck and prime opportunity for stablecoin protocols.
  2. **Moats are Real:** Overcoming established players like Tron requires more than just better tech or lower fees; it demands superior distribution and user migration strategies.
  3. **Align Incentives:** Morpho's structural changes offer a compelling model for aligning team, investor, and token holder interests, potentially setting a new standard for Web3 projects.
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June 12, 2025

Hivemind: Circle Valuation, Pump.Fun Token & What We’re Bullish

Empire

Crypto
Key Takeaways:
  1. Deficit Tailwinds: Persistent global fiscal deficits are expected to continue fueling appreciation in risk assets, including cryptocurrencies.
  2. Stablecoin Tsunami: Stablecoins are not just a crypto niche but a fundamental disruptor to the traditional banking system, with significant investment flowing into leaders like Circle, despite valuation concerns.
  3. App-Layer Alpha: Value is increasingly found in specific applications (like Pump.Fun) and companies leveraging crypto (like Galaxy Digital's AI/crypto blend), sometimes even diverting attention from base-layer L1 tokens.
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June 12, 2025

Why ETH Might Be the Most Mispriced Asset in the World

Bankless

Crypto
Key Takeaways:
  1. ETH's Narrative is Shifting: From "tech stock" to "digital oil" and "store of value," clarifying its multifaceted value.
  2. Supply Squeeze Imminent: Capped issuance plus rising demand driven by network activity and institutional adoption points to a strong supply-demand imbalance.
  3. Massive Re-rating Potential: If ETH achieves a similar status to other global reserve assets, its price could see exponential growth from current levels.
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June 11, 2025

How RLUSD Will Join USDT & USDC

Empire

Crypto
Key Takeaways:
  1. **RLUSD Rising:** Ripple's ambition is clear: make RLUSD a top 3-4 stablecoin by leveraging strategic acquisitions for mass distribution, potentially issuing billions through platforms like Hidden Road.
  2. **Acquisition = Distribution:** Ripple is effectively purchasing its market share by acquiring businesses like Hidden Road and Metaco, creating an embedded network to push RLUSD adoption.
  3. **Stablecoin Selects:** The future stablecoin landscape will likely feature 5-7 major players, not just two, and Ripple is aggressively positioning RLUSD to be one of them.
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June 11, 2025

Crypto's Next Era: TradFi IPOs or Hyperliquid, PumpFun & Solana?

Bankless

Crypto
Key Takeaways:
  1. TradFi Wants In: The success of Circle's IPO demonstrates a massive, untapped demand from traditional markets for regulated crypto exposure, potentially paving the way for a wave of crypto IPOs.
  2. ETH's Dilemma: While Ethereum is the undisputed settlement layer for stablecoins and RWAs, the direct translation of this utility to ETH asset appreciation remains a critical question, hinging on increased on-chain economic velocity.
  3. Apps are Eating: Solana's ecosystem, with stars like Hyperliquid and Pump.fun, shows that "fat applications" can generate enormous revenue and user engagement, potentially capturing more value than the underlying L1s.
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June 11, 2025

What Is Flipcash? | Ted Livingston

Lightspeed

Crypto
Key Takeaways:
  1. Digital Cash, Real Utility: Flipcash aims to make digital money feel like physical cash—instant, easy, and universally acceptable, starting with a seamless USDC experience.
  2. Solana Speed is Key: The app's core "wow" factor of instant transactions relies heavily on Solana's performance, underscoring the blockchain's capability for consumer-facing applications.
  3. Onboarding Solved?: Requiring a small purchase for an account, immediately offset by a USDC bonus, tackles the "empty wallet" problem, driving immediate engagement and demonstrating value.
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