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AI Podcasts

November 17, 2025

Emmett Shear on Building AI That Actually Cares: Beyond Control and Steering

a16z

AI
Key Takeaways:
  1. Stop Trying to “Steer” AGI. The control paradigm is a dead end. The goal isn’t a more obedient tool; it’s a trustworthy teammate. We must shift from engineering control to cultivating care.
  2. Alignment is a Process, Not a Product. True alignment isn't a fixed set of rules. It’s a dynamic process of moral learning, akin to raising a child. AIs that only follow rules are brittle and dangerous.
  3. Build for Cooperation, Not Command. The technical path forward involves training AIs in rich, multi-agent environments where they must learn cooperation and theory of mind—the foundational skills for becoming a good member of a group.
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November 16, 2025

Rawson Haverty presents "US & China AI: Lessons from Across the Pacific" | dAGI Summit 2025

Delphi Digital

AI
Key Takeaways:
  1. US Leads in Capital-Intensive Frontier AI; China Excels at Industrial Diffusion. The US leverages deep capital markets for its massive compute buildout and AGI research, while China uses state direction to embed AI into its vast industrial base via open-source models and hardware.
  2. Market Structure Dictates AI Strategy. The US "efficient oligopoly" model prioritizes global dominance and profit reinvestment by a few players. China's "subjugated swarm" model creates intense domestic competition, driving down prices and accelerating adoption at the cost of profitability.
  3. Geopolitical Tension May Be a Necessary Stabilizer. The competition between the US's freedom-oriented, frontier-pushing approach and China's stability-focused, diffusion-driven model creates a complementary tension that could be essential for navigating the "narrow corridor" between AI-driven totalitarianism and uncontrollable chaos.
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November 13, 2025

How Will AI Change Gaming Development? (A Dev’s Take)

The DCo Podcast

AI
Key Takeaways:
  1. Development timelines are collapsing from months to days. AI allows developers to swap entire asset libraries or generate new game concepts at unprecedented speed, turning a two-month art project into a day's work.
  2. The lifespan of any single game is shrinking. Prepare for a world of disposable entertainment. As AI floods the market with content, the strategy will pivot from creating one long-lasting hit to deploying a rapid succession of engaging experiences.
  3. Games are the next evolution of the attention economy. Just as memes became a core tool for community-building around tokens, easily created games will be the next engine for capturing and directing user attention in a hyper-competitive digital world.
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November 11, 2025

AI Nerves, Crypto Realism, Privacy Coins, & Lessons From Trading

1000x Podcast

AI
Key Takeaways:
  1. Adopt a Stock Picker's Mentality. The crypto market is no longer a monolith where a rising tide lifts all boats. Focus on assets with real products, user growth, and cash flow, as the gap between winners and losers will only widen.
  2. Shorting is a Tactical Assault, Not a Siege. Don't "invest" in a short. The only viable short strategies are tactical, targeting specific events like VC unlocks or news-driven spikes. Otherwise, even "total scams" can 5x against you.
  3. Cultivate a Goldfish's Memory. The most critical trading skill is learning how to change your mind. Cut losing trades, forget the loss (but remember the lesson), and redeploy capital without emotional baggage. Stubbornness is a portfolio killer.
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November 11, 2025

Grant Lee: Building Gamma’s AI Presentation Company to 100 Million Users

a16z

AI
Key Takeaways:
  1. Word-of-mouth isn't a feature; it's the engine. Before spending a dime on marketing, obsess over the first 30 seconds of the user experience until people can't help but share it.
  2. Being different is better than being better. Don't build incrementally better slideware. Redefine the core primitives of your category, as Gamma did by moving beyond the 16x9 slide.
  3. Hire painfully slowly to protect your DNA. Resisting the temptation to scale headcount with user growth is a superpower. The goal isn't to hit a hiring target; it's to hire the best people.
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November 7, 2025

Amjad Masad & Adam D’Angelo: How Far Are We From AGI?

a16z

AI
Key Takeaways:
  1. AGI Is a Definitional Debate. Progress toward an AI that can replace a remote worker is happening fast. However, achieving "true" human-like learning efficiency may require an entirely new paradigm beyond scaling current LLMs.
  2. The New Creator Economy Is Code. AI is turning software development into a mainstream creative pursuit, empowering a new class of solo entrepreneurs who can build what previously required entire teams.
  3. Incumbents Learned Their Lesson. Unlike past tech shifts, today's giants are aggressively adopting AI, making it both a sustaining *and* disruptive force. The market is large enough for both incumbents and startups to create massive value.
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November 6, 2025

Mark Zuckerberg & Priscilla Chan: How AI Will Cure All Disease

a16z

AI
Key Takeaways:
  1. Build the Tools, Not Just the House: CZI’s greatest leverage comes from creating open-source tools and datasets. By building the fundamental infrastructure, they empower the entire scientific community—from academic labs to startups—to accelerate discovery.
  2. Data Is the New Microscope: The future of biology hinges on a tight feedback loop between generating novel, purpose-built datasets and training domain-specific AI models on them. This synergy is unlocking insights that were previously impossible.
  3. Virtual Biology Is the Next Frontier: Simulating biology computationally with "virtual cells" will become the new standard for research, enabling scientists to test riskier hypotheses faster and cheaper, dramatically compressing the timeline for major breakthroughs.
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November 5, 2025

Seeing The Future from AI Companions to Personal Software

a16z

AI
Key Takeaways:
  1. The Interface is the Bottleneck. Today's chatbots are the MS-DOS of AI. The next trillion dollars of value will be unlocked not by the models themselves, but by the new "Windows/Mac OS" interface that makes AI accessible and useful for everyone.
  2. Every Creator Will Build Software. The distinction between a content creator and a software developer is collapsing. The next platforms will empower anyone to build mini-apps, turning software into a new medium for community, expression, and monetization.
  3. Ditch the Voice-Only Dream. The Her-inspired fantasy of a screenless, voice-only AI future is a dead end. The winning AI device will be screen-first, built around an AI-native OS that makes software deeply personal and context-aware.
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November 4, 2025

Rollup TV: Aria Protocol, Money Moves Fast EP 8, Crossmint

The Rollup

AI
Key Takeaways:
  1. Culture is the Newest Yield-Bearing Asset: Arya Protocol proves that intellectual property, from music royalties to digital art, can be tokenized into stable, income-generating investments, moving beyond crypto’s speculative roots.
  2. Fintech's Crypto FOMO is Reshaping Finance: The race is on. Traditional payment giants are rapidly adopting stablecoins, not as a gimmick, but as a critical infrastructure upgrade for building faster, cheaper, and more inclusive global financial products.
  3. Money is Becoming Natively Programmable for AI: The future of commerce and finance will be run by AI agents. Stablecoins provide the missing piece—a programmable, automated payment layer that bypasses the friction of traditional banking, unleashing a new wave of economic activity.
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Crypto Podcasts

October 9, 2025

Andre Cronje: How the SEC Tried to Shut Me Down

The DCo Podcast

Crypto
Key Takeaways:
  1. Regulation by Exhaustion: The SEC's primary weapon was not legal action but a relentless process designed to drain builders' time, energy, and will to continue.
  2. The Target Is Always Moving: Regulators will continuously shift their focus—from token to revenue to the product itself—until they find a viable angle of attack.
  3. Innovation Was the Real Target: This "shotgun approach" against hundreds of projects was a de facto industry crackdown that successfully chased many legitimate builders away, achieving a policy goal without ever going to court.
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October 8, 2025

The BTC/Gold Ratio Is Screaming "Higher"

1000x Podcast

Crypto
Key Takeaways:
  1. Stop Pricing in Fiat: The BTC/Gold ratio is the clearest signal of Bitcoin’s fundamental adoption, stripping away the distortion of dollar debasement.
  2. Mean Reversion Points to $150k+: The established BTC/Gold trend channel since 2023 is screaming higher. A simple return to the channel’s midpoint targets a $150k–$160k Bitcoin price by year-end.
  3. Gold's Rally is Bitcoin's Tailwind: Gold’s new role as a de-dollarization hedge for nations and the subsequent portfolio rebalancing from gold profits into BTC create powerful dual-demand drivers for Bitcoin.
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October 8, 2025

Steady Lads Live From TOKEN2049 in Singapore! w/ Dim Selk

Steady Lads Podcast

Crypto
Key Takeaways:
  1. Profit, Don't HODL. The current market is a trader’s paradise, not an investor’s dream. The strategy is to ride the seasonal Q4 pump and exit by January, refusing to get caught in another brutal bear cycle.
  2. Fade the Old, Farm the New. Capital is mercenary, flowing from established tokens to the next hot airdrop farm or launch. The relentless hunt for volatility means older coins are treated as exit liquidity for the next shiny object.
  3. Unlocks Are the Silent Killer. Before investing, map out the token unlock schedule. Even fundamentally sound projects with strong revenue face a massive gravitational pull on their price from insider and team unlocks.
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September 17, 2025

FinTech Meets Crypto: The Future of Global Payments

Bankless

Crypto
Key Takeaways:
  1. **Stablecoins Are Rebranding Crypto.** The FinTech industry is adopting stablecoin technology not as a niche crypto asset, but as the foundational layer for "FinTech 3.0," poised to overhaul global payments.
  2. **The EVM Is The New COBOL.** Specialized payments chains are standardizing the EVM as the backend for modern finance, creating high-throughput, compliant on-ramps that will bring trillions in TradFi volume on-chain.
  3. **Payments Are Just The Beginning.** Once the world rebuilds its payments infrastructure on stablecoins, the floodgates will open for the complete tokenization of all financial assets, forever blurring the line between crypto and finance.
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September 16, 2025

Collector Crypt: Onchain Capital Markets On Solana | Tuomas Holmberg

Lightspeed

Crypto
Key Takeaways:
  1. Onchain Rails Create New Economies. By digitizing physical assets on high-performance chains like Solana, you eliminate friction around custody, settlement, and global access, unlocking novel business models like the Gotcha Machine.
  2. Real-World Logistics Are the Ultimate Moat. While anyone can build a smart contract, Collector Crypt’s defensibility comes from its physical supply chain—dealer relationships and automated acquisition tools that secure inventory below market price.
  3. Novel Oracles Unlock the Next Wave of DeFi. The future of onchain finance depends on reliably pricing illiquid, real-world assets. Developing proprietary oracles, like Collector Crypt’s, is the first step to building DeFi for everything.
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September 15, 2025

Is It Time to Rotate Out of Crypto?

1000x Podcast

Crypto
Key Takeaways:
  1. **De-Risk Your Alts.** Crypto is showing significant weakness by failing to rally with equities. Ethereum's lower high is a major red flag for the altcoin market; it's time to reduce leverage and concentrate into Bitcoin or cash.
  2. **Hunt for Value in TradFi.** Traditional markets are offering powerful narrative-driven plays with crypto-like upside. Focus on assets like Tesla (robotics), Robinhood (gambling culture), and commodities like uranium (energy independence).
  3. **Fade the ETF Narrative.** The institutional "sugar high" from ETFs is wearing off as the front-running trade becomes crowded and inflows wane. The market needs a new, more durable catalyst to move higher.
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