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AI Podcasts

December 26, 2025

What I learned at the frontier of tech in 2025 (Kelly, Cowen, Wang, Prince)

Azeem Azhar

AI
Key Takeaways:
  1. The Macro Pivot: The transition from weightless software to energy-heavy hardware.
  2. The Tactical Edge: Stop building "wrappers" for model weaknesses.
  3. The Bottom Line: AI value is moving from the model to the grid and the individual reputation.
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December 26, 2025

How AI Will Reshape The Economy In 2026 (a16z Big Ideas)

a16z

AI
Key Takeaways:
  1. The Macro Shift: The Great Re-architecting. As legacy software moats evaporate and industrial supply chains reshore, value is migrating from passive data storage to active execution layers.
  2. The Tactical Edge: Target Archaic Verticals. Identify high-friction industries like mortgage servicing or IT support where the distance between intent and execution is currently measured in days.
  3. The Bottom Line: The next two years will reward those who build systems of action that replace human labor with autonomous agents and software-defined hardware.
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December 27, 2025

Why Scientists Can't Rebuild a Polaroid Camera [César Hidalgo]

Machine Learning Street Talk

AI
Key Takeaways:
  1. The Macro Trend: Economic complexity predicts growth better than current GDP. Capital will move toward "high-letter" economies like India and Indonesia.
  2. The Tactical Edge: Prioritize team retention over documentation. Since knowledge is embodied, losing a core team is equivalent to deleting the source code.
  3. The Bottom Line: Success in the next decade belongs to those who treat knowledge as a living network rather than a digital asset.
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December 26, 2025

⚡️GPT5-Codex-Max: Training Agents with Personality, Tools & Trust — Brian Fioca + Bill Chen, OpenAI

Latent Space

AI
Key Takeaways:
  1. The Macro Shift: Agentic Abstraction. We are moving from Model-as-a-Service to Agent-as-a-Service where the harness is as important as the weights.
  2. The Tactical Edge: Standardize your CLI. Use tools like ripgrep (RG) that models already have "habits" for to see immediate performance gains.
  3. The Bottom Line: The next 12 months will see the end of manual integration engineering as agents become capable of navigating UIs and legacy terminals autonomously.
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December 26, 2025

Steve Yegge's Vibe Coding Manifesto: Why Claude Code Isn't It & What Comes After the IDE

Latent Space

AI
Key Takeaways:
  1. The commoditization of syntax means architectural judgment is the only remaining moat. As the cost of code hits zero the value of intent skyrockets.
  2. Replace your manual refactoring workflows with a burn and rebuild strategy. Use agents to generate entirely new modules instead of patching old ones.
  3. Seniority is no longer a shield against obsolescence. You must spend the next six months building your agentic intuition or risk being replaced by a PhD student with a prompt.
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December 28, 2025

One Year of MCP — with David Soria Parria and AAIF leads from OpenAI, Goose, Linux Foundation

Latent Space

AI
Key Takeaways:
  1. The Macro Evolution: Standardized communication layers are replacing custom API integrations. This commoditizes the connector market and moves value to the models that best utilize these tools.
  2. The Tactical Edge: Standardize your internal data tools using MCP servers today. This ensures your company is ready for autonomous agents that can discover and use your resources without manual API integration.
  3. The Bottom Line: The agentic stack is consolidating around MCP. Interoperability is no longer a feature; it is the foundation for the next decade of AI utility.
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December 26, 2025

How Claude Code Works - Jared Zoneraich, PromptLayer

AI Engineer

AI
Key Takeaways:
  1. The transition from Prompt Engineering to Context Engineering where the goal is keeping the model's workspace small and relevant.
  2. Replace your complex classification prompts with a single Bash tool. Let the agent write its own Python scripts to handle data transformations.
  3. The winners in the agent space will not be those with the most complex logic. They will be the ones who build the best tools for the model to use.
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December 26, 2025

Shipping AI That Works: An Evaluation Framework for PMs – Aman Khan, Arize

AI Engineer

AI
Key Takeaways:
  1. The Macro Shift: From Model-Centric to Eval-Centric. The value is moving from the LLM itself to the proprietary evaluation loops that keep the LLM on the rails.
  2. The Tactical Edge: Export production traces and build a "Golden Set" of 50 hard examples. Use these to run A/B tests on every prompt change before hitting production.
  3. The Bottom Line: Reliability is the product. If you cannot measure how your agent fails, you haven't built a product; you've built a demo.
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December 26, 2025

How AI Will Reshape The Economy In 2026 (a16z Big Ideas)

a16z

AI
Key Takeaways:
  1. The transition from passive data storage to active agentic execution across both financial and industrial sectors.
  2. Target unsexy legacy industries like mortgage servicing or rare earth processing where the margin for improvement is highest.
  3. 2026 marks the year where software eating the world moves from the screen to the physical supply chain and the autonomous agent.
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Crypto Podcasts

September 16, 2025

Collector Crypt: Onchain Capital Markets On Solana | Tuomas Holmberg

Lightspeed

Crypto
Key Takeaways:
  1. Onchain Rails Create New Economies. By digitizing physical assets on high-performance chains like Solana, you eliminate friction around custody, settlement, and global access, unlocking novel business models like the Gotcha Machine.
  2. Real-World Logistics Are the Ultimate Moat. While anyone can build a smart contract, Collector Crypt’s defensibility comes from its physical supply chain—dealer relationships and automated acquisition tools that secure inventory below market price.
  3. Novel Oracles Unlock the Next Wave of DeFi. The future of onchain finance depends on reliably pricing illiquid, real-world assets. Developing proprietary oracles, like Collector Crypt’s, is the first step to building DeFi for everything.
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September 15, 2025

Is It Time to Rotate Out of Crypto?

1000x Podcast

Crypto
Key Takeaways:
  1. **De-Risk Your Alts.** Crypto is showing significant weakness by failing to rally with equities. Ethereum's lower high is a major red flag for the altcoin market; it's time to reduce leverage and concentrate into Bitcoin or cash.
  2. **Hunt for Value in TradFi.** Traditional markets are offering powerful narrative-driven plays with crypto-like upside. Focus on assets like Tesla (robotics), Robinhood (gambling culture), and commodities like uranium (energy independence).
  3. **Fade the ETF Narrative.** The institutional "sugar high" from ETFs is wearing off as the front-running trade becomes crowded and inflows wane. The market needs a new, more durable catalyst to move higher.
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September 15, 2025

Bittensor TAO :: Community Q+A :: Sub-Subnets, Deregistration, Yuma Consensus + more

The Opentensor Foundation | Bittensor TAO

Crypto
Key Takeaways
  1. Subnets are becoming more complex. The introduction of sub-subnets will allow for more sophisticated, multi-faceted incentive mechanisms within a single subnet, effectively turning them into "mixtures of experts."
  2. Performance is now paramount. Subnet deregistration creates a "perform or perish" dynamic. Underperforming subnets risk being automatically removed, with their assets returned to token holders as TAO.
  3. Decentralization is on the horizon. The shift to Proof-of-Stake and a formal on-chain governance structure are actively being developed, marking a deliberate move toward placing control in the hands of the community.
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September 15, 2025

How to Invest in The Debasement Era

Bankless

Crypto
Key Takeaways:
  1. Recessions Are Canceled, Inflation Is Not: Perpetual government stimulus will prevent deep downturns, but it locks in higher inflation. Plan for a ~3% floor and a market that swings between boom and stagflation.
  2. The US Super Cycle Is Over: After a historic 15-year run, US market dominance has peaked. The next decade’s alpha will be found in undervalued international markets benefiting from a weakening dollar.
  3. Build a Debasement-Proof Portfolio: Ditch long-duration bonds. Hold cash for opportunity, stay invested in global equities, and overweight hard assets like gold and crypto to preserve purchasing power.
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September 14, 2025

Can Prediction Markets Outpace Securities Trading? With Farrokh and Carlos Domingo

The Rollup

Crypto
Key Takeaways:
  1. **Prediction markets are not a niche crypto game; they are a multi-trillion dollar industry gunning for the securities market** by financializing the world's most valuable asset: information.
  2. **True tokenization will be won on open, permissionless blockchains** that enable new market structures, not closed systems offering mere efficiency gains. Institutions like BlackRock are already betting on this "open internet" thesis.
  3. **Creator tokens are a flawed model with a built-in expiration date tied to relevance.** The smarter trade is to own the casino (the platform's token), not the individual player's chips.
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September 12, 2025

The Biggest Winner from Hyperliquid’s USDH | Weekly Roundup

Empire

Crypto
Key Takeaways:
  1. Distribution is the New Kingmaker. Protocols with significant user bases and transaction volume (like Hyperliquid) now have the leverage to command value from stablecoin issuers and other service providers, not the other way around.
  2. The Stablecoin Revenue Model is Broken. The era of stablecoin issuers keeping 100% of the yield from reserves is over. Expect a race to the bottom on revenue sharing, forcing issuers to innovate on product rather than just collecting yield.
  3. The Crypto IPO Window is Wide Open. With Figure’s successful public offering and Gemini’s upcoming listing, public markets are showing a strong appetite for crypto-native businesses, likely triggering a wave of IPOs from companies like Kraken, BitGo, and others.
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