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AI Podcasts

July 21, 2025

Pushing compute to the limits of physics

Machine Learning Street Talk

AI
Key Takeaways:
  1. Hardware is the New Frontier. The scaling race isn't about building more data centers for the same old chips. The next 1000x improvement will come from a fundamental paradigm shift that works with physics, not against it.
  2. Noise is a Feature, Not a Bug. The future of efficient computing lies in harnessing stochasticity. The "noise" we spend billions to suppress in classical chips is the very resource that can power probabilistic AI models with unparalleled efficiency.
  3. Prepare for an Algorithmic Renaissance. The dominance of Transformers is a temporary state dictated by current hardware. As thermodynamic computers become available, developers and researchers should dust off their probabilistic ML textbooks—the algorithms of tomorrow will look very different.
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July 21, 2025

José Macedo and Pondering Durian: The Birth of Delphi Intelligence

Delphi Digital

AI
Key Takeaways:
  1. Invest in AI's Tailwinds: The essential question for any AI investment is: "Does this business get better as foundation models improve?" Companies fighting against the current of AI's scaling laws are on the wrong side of a powerful trade.
  2. The "Mag 7" Will Expand, Not Just Turn Over: AI is not a zero-sum game for incumbents. The total addressable market is set to 10x as AI drives labor costs toward zero, creating room for a "Mag 25" and turning today's $500B companies into tomorrow's $5T behemoths.
  3. Private Market Alpha Exists, But Edge is Paramount: The private AI market cap is a mere ~$700B, signaling massive growth potential. However, like in crypto, investors must be paranoid about their "edge," as the best deals require deep ecosystem access to avoid negative selection.
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July 21, 2025

The Future of Software Development - Vibe Coding, Prompt Engineering & AI Assistants

a16z

AI
Key Takeaways:
  1. **AI Isn't a Feature; It's a New Infrastructure Primitive.** For the first time, developers are outsourcing logic, not just resources. This fundamentally changes how software is built, valued, and sold.
  2. **Abandon Zero-Sum Thinking.** The AI market is in a massive expansion phase, not a consolidation battle. Value is accruing at every layer of the stack simultaneously; assuming one layer's gain is another's loss is a flawed thesis.
  3. **The Future is More Developers, Not Fewer.** AI tools augment productivity and lower the barrier to entry. This elevates the developer's role to focus on product design and workflow definition—the *real* hard problem in software.
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July 20, 2025

Hash Rate - Brief #1 - Chutes

Hash Rate pod - Bitcoin, AI, DePIN, DeFi

AI
Key Takeaways:
  1. **A Killer Value Prop:** Chutes makes deploying powerful AI models 85% cheaper and as easy as building a website on Squarespace.
  2. **The Investor's Dilemma:** While all revenue is used to buy back the Chutes alpha token, this currently covers only 10% of the daily token emissions. The token's price stability is heavily dependent on external market demand outstripping this inflation.
  3. **Watch for Catalysts:** Two key events could dramatically increase buy pressure: the imminent launch of BitTensor subnet tokens on Solana and an anticipated wave of institutional capital from newly formed crypto hedge funds.
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July 20, 2025

Hash Rate - Ep 122 - ZEUS Weather - Subnet 18 $TAO

Hash Rate pod - Bitcoin, AI, DePIN, DeFi

AI
Key Takeaways:
  1. **Specialization Unlocks Performance.** ZEUS proves that a decentralized network of specialized AI agents can outperform monolithic, state-of-the-art models, achieving a nearly 40% lower error rate in weather forecasting.
  2. **Revenue Sharing is the Next Evolution.** The plan to distribute API revenue directly to network participants in stablecoins represents a major step toward sustainable subnet economies, moving beyond token buybacks and emission-based rewards.
  3. **The Valuation Gap is the Opportunity.** Despite massive potential, subnets have extremely low market caps compared to their Web2 equivalents. For long-term believers, this asymmetry presents a compelling, albeit early, investment thesis.
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July 19, 2025

SN52 :: Tensorplex Dojo :: High-Quality Human-Generated Datasets on Bittensor

Opentensor Foundation

AI
Key Takeaways:
  1. Human Intelligence is the Ultimate Moat: In an era of synthetic data, Dojo is creating a defensible moat by generating proprietary, high-quality human preference data. This is the raw material for the next generation of fine-tuned, specialized models.
  2. A New Paradigm for Validation: Dojo’s mechanism of using subtle "perturbations" to test labelers is a breakthrough. It solves the cold start problem of validating subjective human feedback in a decentralized network.
  3. The Future is Human-Agentic Collaboration: Dojo is evolving from a data-generation subnet to a platform for human-agentic workflows, with applications in robotics, video analytics, and 3D generation. In the long term, it aims to be a crucial tool for aligning AI with human values.
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July 18, 2025

Tech Executives: AI Has Changed SAAS Forever (Don't Fall Behind)

a16z

AI
Key Takeaways:
  1. Your Pricing Model Is Now a Dynamic Weapon. The five-year pricing plan is dead. You must build the infrastructure and culture for constant experimentation and rapid iteration. If you’re not re-evaluating your model quarterly, you're falling behind.
  2. This Is a CEO-Level Mandate. Shifting to usage-based pricing is a full-company transformation that requires top-down vision. The CEO must act as the "pricing dictator" to align sales, product, and finance around a unified strategy of value creation and capture.
  3. Your Product Team Now Owns Revenue. In a usage-based world, the core value metric *is* your revenue. Product and engineering teams must become obsessed with driving the specific usage that customers pay for, making their impact on the bottom line completely objective.
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July 17, 2025

Can AI Be Creative? With AI Artists Mario Klingemann and Shavonne Wong

The People's AI

AI
Key Takeaways:
  1. AI as a System, Not a Tool: Advanced AI art projects are not just prompt-driven tools but autonomous systems. They use feedback loops (DAOs, user interaction) to develop their own "taste" and creative trajectory, aiming for a level of agency beyond simple human puppeteering.
  2. AI Reveals Human Vulnerabilities: AI companions act as a social mirror, showing that humans fundamentally crave connection and non-judgmental spaces. We are turning to AI to fulfill core needs that are often unmet in our human-to-human relationships.
  3. The Artist's Dilemma: Adapt or Perish: Resisting AI is becoming a losing battle. The future for artists isn't about competing with AI on replication but on finding what AI can't do, critiquing it from within, or carving out a niche for "100% human-made" work in a world of synthetic media.
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July 16, 2025

The Humble Truths Behind Bombastic AI Papers

Machine Learning Street Talk

AI
Key Takeaways:
  1. Benchmarks are broken. The ML community can no longer rely on leaderboards as a proxy for truth. The new frontier is developing robust, qualitative explanations for why models succeed or fail.
  2. Embrace the illusion. The most effective models aren’t finding universal laws but are constructing powerful, computationally efficient illusions of them. Progress lies in refining these illusions, not in a futile search for Platonic perfection.
  3. Think like a physicist. The future of foundational AI research is to treat models as complex physical systems. The task is to design parametric models where stochastic processes, like SGD, can efficiently "relax" into a state that approximates the data distribution.
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Crypto Podcasts

October 22, 2025

Is the Cycle Over, Portfolio Psychology, & Prediction Market Alpha

1000x Podcast

Crypto
Key Takeaways:
  1. Fade the Cycle Narrative: The influx of new, cycle-agnostic capital via ETFs means the market's rhythm has changed. Sideways price action is the new up, signaling strong demand is absorbing OG selling.
  2. Buy Picks, Shovels, and Yield: The era of riding hyped, valueless memecoins is over. The durable strategy is to own the infrastructure (Robin Hood) or assets that generate and return real fees to holders (Shuffle, Aerodrome).
  3. Arbitrage Information Gaps: Find your edge in niche markets. Exploitable alpha exists in prediction markets, whether through contrarian betting, language advantages, or AI-powered analysis.
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October 22, 2025

State Of Crypto 2025 | a16z Crypto — Eddy Lazzarin & Daren Matsuoka

Bankless

Crypto
Key Takeaways:
  1. Stablecoins Are The Trojan Horse. They have achieved undeniable product-market fit, rivaling legacy payment rails and becoming a key tool for U.S. dollar dominance. They are the gateway for both institutional players and everyday users in emerging markets.
  2. Usage is Divorced From Speculation. For the first time, practical on-chain activity is being driven by users in developing nations who *need* crypto, while speculation is led by those in developed nations who *want* it. The next bull run will be driven by products that bridge this divide.
  3. The Bottleneck is No Longer Technology. With scalability largely solved (blockchains now process over 3,400 TPS), the primary barriers to adoption have shifted from infrastructure to product design, user experience, and regulatory clarity.
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October 22, 2025

MegaETH Co-Founder: How We Rebuilt Ethereum From the Ground Up

The DCo Podcast

Crypto
Key Takeaways:
  1. Question Sacred Cows: The path to breakthrough performance lies in challenging foundational assumptions. For Layer 2s, this means recognizing that sequencer decentralization may be a solution in search of a problem.
  2. Focus and Outsource: MegaETH’s strategy is simple: be the best at performance by outsourcing the hardest part—consensus—to Ethereum. This allows them to build a hyper-optimized execution environment without compromising on security.
  3. Hire Outside the Echo Chamber: The next major blockchain innovation may not come from a crypto veteran. Expertise from adjacent fields like low-latency computing can provide the first-principles thinking needed to solve the industry’s most entrenched problems.
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October 22, 2025

Institutional Demand for Crypto is Accelerating | Matt Hougan

Forward Guidance

Crypto
Key Takeaways:
  1. **Allocations Are Multiplying:** The standard institutional crypto allocation is moving from a timid 1% to a more confident 3-5%, driven by crypto's declining volatility and the fading fear of a "go-to-zero" event.
  2. **The ETF Universe is Exploding:** New SEC guidelines will unleash a wave of crypto ETFs, from single assets to index funds. This will reshape market structure and provide traditional investors with simple on-ramps to the entire ecosystem.
  3. **Stablecoins are the Real Trojan Horse:** Beyond Bitcoin, institutional demand for stablecoins is immense. They aren't just an asset; they are recognized as the critical settlement layer for a tokenized, 24/7 global market.
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October 21, 2025

Inside Coinbase’s $375m Acquisition of Echo | Shan Aggarwal

Empire

Crypto
Key Takeaways:
  1. Becoming the Capital Stack: Coinbase's endgame is not just being a crypto exchange but providing the full, end-to-end infrastructure for any company—crypto or traditional—to issue, manage, and raise capital on-chain.
  2. Acquire Missionaries, Not Mercenaries: Their M&A success hinges on a proactive, culture-first approach. They identify strategic needs, hunt for the best teams, and integrate them deeply, ensuring founders stay long after their earnouts expire.
  3. Prediction Markets are the Next Trojan Horse: Coinbase is betting big on prediction markets to onboard the next wave of mainstream users, using familiar activities like sports betting as an accessible entry point into the crypto ecosystem.
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October 21, 2025

What's Happening to Crypto Markets? The Onchain Data That Explains Everything

Bankless

Crypto
Key Takeaways:
  1. Leverage Overload, Fundamental Weakness. Record leverage created a "house of cards" structure. Without strong underlying spot volume and new buyers, the market became highly susceptible to cascading liquidations.
  2. The Profits Are In. Long-term Bitcoin holders have already cashed out nearly twice the profit they did last cycle ($900B vs. $500B), indicating the "wealth distribution" phase is well underway.
  3. The Line in the Sand. The key level to watch is Bitcoin's 50-week moving average (around $102k). As long as Bitcoin holds above it, the bull market structure remains intact; two weekly closes below it would be a strong confirmation that the cycle is over.
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