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AI Podcasts

December 17, 2025

Rethinking Pre-Training for Agentic AI [Aakanksha Chowdhery] - 759

The TWIML AI Podcast with Sam Charrington

AI
Key Takeaways:
  1. Pre-Training is the New Frontier: The next leap in AI capabilities, particularly for agentic systems, will come from fundamental advancements in pre-training, not just post-training tweaks.
  2. Builders & Investors: Focus on teams rethinking loss objectives, curating high-quality reasoning data, and developing dynamic benchmarks for agentic capabilities. Be wary of "agentic" claims that lack foundational pre-training innovation.
  3. The "So What?": Over the next 6-12 months, expect a push for new benchmarks and data strategies that explicitly train models for multi-step planning, long-form reasoning, and error recovery, moving beyond simple next-token prediction.
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December 16, 2025

What We Learned Deploying AI within Bloomberg’s Engineering Organization – Lei Zhang, Bloomberg

AI Engineer

AI
Key Takeaways:
  1. Strategic Implication: AI fundamentally changes the economics of software development. Organizations must re-evaluate what constitutes "high-quality" engineering and adapt their processes.
  2. Builder/Investor Note: Prioritize platforms that provide guardrails and guidance for AI tool usage, focusing on deterministic verification and robust testing. Uncontrolled AI deployment risks technical debt.
  3. The "So What?": The next 6-12 months will see a bifurcation: companies that strategically integrate AI into their engineering culture and platforms will gain significant efficiency, while those that don't will struggle with quality and adoption.
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December 16, 2025

Your Support Team Should Ship Code – Lisa Orr, Zapier

AI Engineer

AI
Key Takeaways:
  1. Workflow Automation is the New Frontier: The real value of AI in developer tools comes from orchestrating entire workflows, not just individual point solutions.
  2. Embed for Adoption: Tools must integrate seamlessly into existing workflows and IDEs (like Cursor) to achieve high usage.
  3. Support as a Code-Shipping Powerhouse: Empowering non-traditional roles with AI-driven code generation leverages their unique, real-time context, creating significant operational leverage.
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December 17, 2025

Code World Model: Building World Models for Computation – Jacob Kahn, FAIR Meta

AI Engineer

AI
Key Takeaways:
  1. Semantic Shift: The future of AI in code moves from text generation to deep semantic understanding and execution simulation.
  2. Builder Opportunity: Develop next-generation debugging tools and code agents that leverage internal simulation for faster, more efficient development cycles.
  3. Investor Focus: Prioritize models and platforms that demonstrate explicit execution modeling, as this capability will redefine software development and create new market leaders.
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December 17, 2025

AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs

AI Engineer

AI
Key Takeaways:
  1. Infrastructure Shift: AI-driven kernel optimization addresses a critical bottleneck in scaling AI compute, enabling more efficient use of diverse hardware.
  2. Builder/Investor Note: Focus on solutions with robust, hardware-verified performance metrics and a clear human-in-the-loop strategy. AI is a powerful tool for automating optimization, not a magic bullet for novel algorithmic breakthroughs.
  3. The "So What?": This technology frees expert engineers from tedious optimization, allowing them to focus on higher-level research and truly innovative algorithmic design, accelerating the pace of AI development in the next 6-12 months.
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December 16, 2025

Finding The 1% of Stocks That Matter | Henry Ellenbogen Interview

Invest Like The Best

AI
Key Takeaways:
  1. Strategic Implication: The era of "free money" inflated the number of perceived compounders; a return to positive real rates demands a sharper focus on businesses demonstrating genuine financial discipline and competitive advantage.
  2. Builder/Investor Note: Seek out "Act 2" entrepreneurs and companies that can leverage AI to transform existing physical or IP-based advantages, not just create new AI products. Be prepared to buy more when market sentiment turns negative on strong businesses.
  3. The "So What?": The next 6-12 months will differentiate companies that merely adopt AI from those that strategically integrate it to build durable, uncatchable cost and distribution advantages.
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December 17, 2025

“How We Can Eliminate Crime” | Ben Horowitz and Garrett Langley

a16z

AI
Key Takeaways:
  1. The Future of Policing is Intelligent: Integrating AI, drones, and smart cameras creates a precise, accountable, and safer policing model for both officers and communities.
  2. Invest in the "How": Builders and investors should focus on technologies that enhance certainty of capture, streamline judicial processes, and support public-private partnerships to modernize urban safety infrastructure.
  3. Safety Fuels Mobility: Eliminating crime is not just about law enforcement; it's about restoring the fundamental safety required for economic mobility and a functional society.
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December 18, 2025

Two Futures | Runtime 2025

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next decade's value will accrue to those building foundational AI infrastructure and the "invisible layers" that connect intelligent systems.
  2. Builder/Investor Note: Focus capital and talent on core AI models, specialized domain intelligence, and the underlying computational fabric. Superficial applications risk rapid commoditization.
  3. The So What?: This is the defining period for the architecture of global intelligence. Participation now determines future influence and relevance.
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December 16, 2025

⚡️Jailbreaking AGI: Pliny the Liberator & John V on Red Teaming, BT6, and the Future of AI Security

Latent Space

AI
Key Takeaways:
  1. Strategic Shift: AI security must move beyond superficial guardrails to a full-stack, offensive red-teaming approach that accounts for the expanding attack surface of AI agents and their tool access.
  2. Builder/Investor Note: Builders should prioritize integrating offensive security early in development. Investors should be wary of "security theater" and favor solutions that embrace open-source collaboration and address the entire AI application stack.
  3. The "So What?": The accelerating pace of AI development means static security solutions will quickly become obsolete. Proactive, community-driven, and full-stack security research is essential for navigating the next 6-12 months of AI evolution.
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Crypto Podcasts

June 20, 2025

Macro Uncertainty, Circle’s Surge, and Prediction Market Utility | Roundup

Bell Curve

Crypto
Key Takeaways:
  1. Selective Bets Over Broad Sprees: Forget throwing darts; the crypto market now rewards surgical precision. Focus on projects with strong fundamentals and demonstrable traction, as "hyper dispersion" is the new norm.
  2. Public Equities as a Crypto Proxy: With limited direct, high-quality crypto IPOs, existing listed entities like Circle and Coinbase are soaking up institutional and retail interest, mimicking "alt season" dynamics in traditional markets.
  3. Pragmatism Pays: The industry is shedding ideological baggage. Successful projects will meet existing market needs, provide clear disclosures, and avoid outdated tokenomic "tricks." Prediction markets are an emerging utility to watch.
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June 20, 2025

Token Transparency and The Hot Ball of Money (Hyperliquid/Circle) | Weekly Roundup

Empire

Crypto
Key Takeaways:
  1. **Transparency is Now Table Stakes:** Projects neglecting robust disclosure standards, like those promoted by the new Token Transparency Framework, will face escalating investor scrutiny and skepticism.
  2. **Public Markets: Crypto's Current Darling (But For How Long?):** Expect continued capital inflow and outperformance from regulated, publicly traded crypto entities before a potential, broader token market resurgence.
  3. **Real Value is Built on Fundamentals & Community:** Platforms like Hyperliquid, showcasing operational efficiency, potent tokenomics, and community wealth creation, are forging lasting value that transcends fleeting market trends.
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June 20, 2025

How the GENIUS Act Brings Stablecoins Mainstream | JP Morgan JPMD

Bankless

Crypto
Key Takeaways:
  1. Stablecoin Surge: The GENIUS Act is set to unleash trillions in stablecoin value, positioning dollar-backed digital assets as a global financial linchpin and reinforcing US dollar networks.
  2. ETF Explosion Imminent: Prepare for a diversified crypto ETF market in 2025, as assets like Solana and Dogecoin likely gain approval, testing the true depth of institutional appetite.
  3. Super App Showdown: The battle for your financial future is on, with Coinbase and Robinhood racing to build all-in-one platforms blending traditional finance with on-chain crypto services.
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June 20, 2025

The Rise Of Crypto's App Ecosystem Mike Dudas

Lightspeed

Crypto
Key Takeaways:
  1. **Revenue is King**: The "revenue meta" isn't a meme; it's the future. Invest in applications and protocols generating real cash flow.
  2. **Solana's DeFi Gap is an Opportunity**: Solana needs robust, user-friendly DeFi, especially perps. Building best-in-class products here is a massive opportunity, even if not unseating current L2 leaders.
  3. **IPOs & M&A Signal Maturation**: The success of Circle’s IPO and increasing M&A activity point to a maturing industry where equity value is re-emerging, offering alternative liquidity paths beyond token launches.
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June 19, 2025

Crypto Options Are Broken

Forward Guidance

Crypto
Key Takeaways:
  1. Listed is Better (For Now): For functional crypto options, look to products on established, regulated exchanges with competitive market-making; on-chain options are largely unworkable due to poor liquidity and structure.
  2. US Spot Market Needs a Shake-Up: The high costs and concentration in US spot crypto trading stifle accessibility; more competition is essential.
  3. Market Structure is Destiny: The design of a market—its rules, incentives, and competitive landscape—ultimately determines execution quality and cost, far more than the underlying asset itself.
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June 19, 2025

Institutional Capital Is Reshaping Crypto | Analyst Round Table

0xResearch

Crypto
Key Takeaways:
  1. Fundamentals First: The "revenue meta" is here to stay; projects without real earnings or clear paths to profitability will struggle.
  2. Institutions are Driving: With institutional players dominating trading volumes, expect crypto valuations to increasingly align with traditional financial metrics and scrutiny.
  3. Value Accrual is King: Tokens must demonstrate how they capture and return value to holders; mechanisms like revenue share and buybacks are becoming non-negotiable.
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