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AI Podcasts

February 5, 2026

Mustafa Suleyman — Nature, humans, tools… and now a fourth class

Azeem Azhar

AI
Key Takeaways:
  1. The exponential reduction in the cost of intelligence is transforming AI from a mere tool into a "hyperobject" with quasi-human capabilities, forcing society to adapt from a scarcity-based operating system to one of intelligence abundance.
  2. Cultivate "AI muscle" by actively experimenting with AI tools, understanding their capabilities and limitations, and pushing their boundaries. This hands-on engagement is the best inoculation against "AI psychosis" and prepares you for a world where AI is ubiquitous.
  3. AI's rapid proliferation and increasing autonomy demand immediate, collective action from governments, companies, and individuals to establish clear boundaries and ensure human control. Ignoring this "fourth class" of being risks societal instability and the erosion of human agency over the next 6-12 months.
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February 6, 2026

From $0 to $11B: The ElevenLabs Story

a16z

AI
Key Takeaways:
  1. The computing paradigm is shifting from visual-centric to auditory-first, driven by AI's ability to process raw audio data for emotional depth and contextual understanding. This opens new frontiers for immersive experiences and global communication.
  2. Invest in or build solutions that prioritize raw audio data processing and multimodal AI integration. Focus on applications where emotional nuance and natural interaction create a distinct user experience.
  3. Voice AI, particularly with ElevenLabs' approach to emotional intelligence, is not just an incremental improvement; it is a foundational shift that will redefine human-computer interaction and unlock massive markets in education, entertainment, and global connectivity over the next 6-12 months.
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February 6, 2026

A New Era of Context Memory with Val Bercovici from WEKA

Semi Doped

AI
Key Takeaways:
  1. AI's memory demands invert data center design, moving from storage-first to memory-first. High-speed networks and NVMe flash are now core memory tiers.
  2. Fund software-defined memory solutions like WEKA's Axon and Augmented Memory Grid. These convert existing NVMe drives into high-performance context memory.
  3. Persistent, rapid KV cache access through "Token Warehouses" will determine AI application and agent deployment profitability over the next 6-12 months.
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February 5, 2026

Goodfire AI’s Bet: Interpretability as the Next Frontier of Model Design — Myra Deng & Mark Bissell

Latent Space

AI
Key Takeaways:
  1. AI is moving from opaque, data-driven systems to transparent, intentionally designed agents. This shift is driven by the need for reliability, safety, and the ability to extract novel insights from increasingly powerful models.
  2. Invest in tools and research that provide granular control over AI internals, like Goodfire's platform. This enables precise customization, reduces unintended behaviors, and accelerates scientific discovery in critical domains.
  3. The future of AI isn't just about bigger models; it's about smarter, more controllable ones. Understanding and directly influencing AI's "mind" will be a competitive differentiator and a prerequisite for deploying AI in high-stakes, real-world applications over the next 6-12 months.
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February 5, 2026

She Raised $64M to Build an AI Math Prodigy | Carina Hong, CEO of Axiom

Weights & Biases

AI
Key Takeaways:
  1. The era of "good enough" probabilistic AI for critical systems is ending; the market demands provable correctness. Axiom Math's approach signals a return to formal methods, supercharged by AI, addressing the verification bottleneck in software and hardware.
  2. Investigate formal verification tools for safety-critical code generation, hardware design, and legacy code migration. Prioritize solutions combining AI generation with deterministic proof for speed and certainty.
  3. Formally verifying complex systems with AI will redefine trust in software and hardware. Companies integrating these capabilities gain a competitive advantage, reducing bugs, accelerating development, and meeting regulatory demands over the next 6-12 months.
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February 4, 2026

Ep#61: 1x World Model

RoboPapers

AI
Key Takeaways:
  1. The scaling laws seen in large language and video models are now extending to physical robotics. Internet-scale human video data, combined with humanoid morphology, is creating a new paradigm for robot generalization.
  2. Invest in or build systems that prioritize multi-stage data pipelines, especially those incorporating diverse egocentric data. This approach is proving key to unlocking zero-shot capabilities in physical AI.
  3. World models are not just a research curiosity; they are a practical tool for accelerating robot deployment. Their ability to generalize and act as learned simulators will redefine how robots are trained, tested, and ultimately integrated into our daily lives over the next 6-12 months.
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February 5, 2026

Introducing 4D Creation Open Beta and the Future of Gaming with Roblox CEO Dave Baszucki

No Priors: AI, Machine Learning, Tech, & Startups

AI
Key Takeaways:
  1. The digital experience economy is moving from static content to dynamic, AI-driven co-experience platforms, where user interaction data becomes the core asset for training next-generation virtual intelligence.
  2. Invest in platforms that offer robust, cloud-connected infrastructure and proprietary, vectorized user data for AI training, as these will be the engines for future immersive content and agentic AI development.
  3. Roblox's long-term vision, powered by its unique data moat and AI investments, positions it to define the future of virtual co-experience, making it a critical player to watch for investors and builders in the AI and gaming space over the next 6-12 months.
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February 5, 2026

Mustafa Suleyman — Nature, humans, tools… and now a fourth class

Azeem Azhar

AI
Key Takeaways:
  1. The exponential reduction in the cost of intelligence, coupled with open-source proliferation, is pushing AI into every corner of society, creating a collective action problem where market incentives for "engaging" AI clash with the need for societal safety and control.
  2. Get hands-on with AI now. "Vibe coding" and actively experimenting with AI tools builds "AI muscle," inoculating users against psychosis risks and building a deeper understanding of AI's capabilities and limitations.
  3. AI is here to stay and will redefine work and interaction. Understanding its "hyperobject" nature, advocating for clear regulatory boundaries, and actively engaging with the technology are critical for navigating the near future without falling for its simulated charms.
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February 4, 2026

Ozempic Won't Solve America's Obesity Problem

a16z

AI
Key Takeaways:
  1. The US healthcare system is shifting from a reactive, acute care model to a proactive, preventative one.
  2. Build infrastructure that financially incentivizes preventative lifestyle interventions.
  3. The next decade will see hundreds of billions of dollars redirected towards lifestyle interventions.
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Crypto Podcasts

October 24, 2025

Was Coinbase's Echo Acquisition a Good Deal? | Weekly Roundup

Empire

Crypto
Key Takeaways:
  1. Capital Formation is the New Battleground: Coinbase’s Echo deal is a $400M bet to own the token launch pipeline, directly challenging Binance's Launchpad dominance.
  2. Banks are Officially on Defense: The Fed’s "skinny master account" proposal threatens to let fintechs bypass banks entirely, a disruption so real that bank CEOs are publicly admitting innovators will win.
  3. Prediction Markets are Going Mainstream: DraftKings' partnership with Polymarket validates the model as a legitimate workaround for complex state-level gambling laws, signaling a massive new distribution channel.
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October 24, 2025

Live Weekly Roundup With Kevin Ricoy

Lightspeed

Crypto
Key Takeaways:
  1. Sell the News, Buy the Self-Own. Eclipse’s price action demonstrates that in crypto, counter-narrative marketing can be more effective than traditional hype. When a project publicly acknowledges its own failures, it can signal a market bottom.
  2. Culture is Strategy. The contrast between Ethereum’s perceived complacency and Solana’s hungry underdog ethos directly impacts developer incentives and innovation speed. Ecosystems with a clear, aggressive mission attract and retain talent differently.
  3. Watch the SKR Token. As only the second token from Solana Labs, the SKR launch carries significant reputational weight. Investors should monitor its mechanics, as it will likely set a new standard for ecosystem projects launched by a parent company.
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October 22, 2025

Is the Cycle Over, Portfolio Psychology, & Prediction Market Alpha

1000x Podcast

Crypto
Key Takeaways:
  1. Fade the Cycle Narrative: The influx of new, cycle-agnostic capital via ETFs means the market's rhythm has changed. Sideways price action is the new up, signaling strong demand is absorbing OG selling.
  2. Buy Picks, Shovels, and Yield: The era of riding hyped, valueless memecoins is over. The durable strategy is to own the infrastructure (Robin Hood) or assets that generate and return real fees to holders (Shuffle, Aerodrome).
  3. Arbitrage Information Gaps: Find your edge in niche markets. Exploitable alpha exists in prediction markets, whether through contrarian betting, language advantages, or AI-powered analysis.
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October 22, 2025

State Of Crypto 2025 | a16z Crypto — Eddy Lazzarin & Daren Matsuoka

Bankless

Crypto
Key Takeaways:
  1. Stablecoins Are The Trojan Horse. They have achieved undeniable product-market fit, rivaling legacy payment rails and becoming a key tool for U.S. dollar dominance. They are the gateway for both institutional players and everyday users in emerging markets.
  2. Usage is Divorced From Speculation. For the first time, practical on-chain activity is being driven by users in developing nations who *need* crypto, while speculation is led by those in developed nations who *want* it. The next bull run will be driven by products that bridge this divide.
  3. The Bottleneck is No Longer Technology. With scalability largely solved (blockchains now process over 3,400 TPS), the primary barriers to adoption have shifted from infrastructure to product design, user experience, and regulatory clarity.
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October 22, 2025

MegaETH Co-Founder: How We Rebuilt Ethereum From the Ground Up

The DCo Podcast

Crypto
Key Takeaways:
  1. Question Sacred Cows: The path to breakthrough performance lies in challenging foundational assumptions. For Layer 2s, this means recognizing that sequencer decentralization may be a solution in search of a problem.
  2. Focus and Outsource: MegaETH’s strategy is simple: be the best at performance by outsourcing the hardest part—consensus—to Ethereum. This allows them to build a hyper-optimized execution environment without compromising on security.
  3. Hire Outside the Echo Chamber: The next major blockchain innovation may not come from a crypto veteran. Expertise from adjacent fields like low-latency computing can provide the first-principles thinking needed to solve the industry’s most entrenched problems.
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October 22, 2025

Institutional Demand for Crypto is Accelerating | Matt Hougan

Forward Guidance

Crypto
Key Takeaways:
  1. **Allocations Are Multiplying:** The standard institutional crypto allocation is moving from a timid 1% to a more confident 3-5%, driven by crypto's declining volatility and the fading fear of a "go-to-zero" event.
  2. **The ETF Universe is Exploding:** New SEC guidelines will unleash a wave of crypto ETFs, from single assets to index funds. This will reshape market structure and provide traditional investors with simple on-ramps to the entire ecosystem.
  3. **Stablecoins are the Real Trojan Horse:** Beyond Bitcoin, institutional demand for stablecoins is immense. They aren't just an asset; they are recognized as the critical settlement layer for a tokenized, 24/7 global market.
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