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AI Podcasts

December 26, 2025

What I learned at the frontier of tech in 2025 (Kelly, Cowen, Wang, Prince)

Azeem Azhar

AI
Key Takeaways:
  1. The Macro Pivot: The transition from weightless software to energy-heavy hardware.
  2. The Tactical Edge: Stop building "wrappers" for model weaknesses.
  3. The Bottom Line: AI value is moving from the model to the grid and the individual reputation.
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December 26, 2025

How AI Will Reshape The Economy In 2026 (a16z Big Ideas)

a16z

AI
Key Takeaways:
  1. The Macro Shift: The Great Re-architecting. As legacy software moats evaporate and industrial supply chains reshore, value is migrating from passive data storage to active execution layers.
  2. The Tactical Edge: Target Archaic Verticals. Identify high-friction industries like mortgage servicing or IT support where the distance between intent and execution is currently measured in days.
  3. The Bottom Line: The next two years will reward those who build systems of action that replace human labor with autonomous agents and software-defined hardware.
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December 27, 2025

Why Scientists Can't Rebuild a Polaroid Camera [César Hidalgo]

Machine Learning Street Talk

AI
Key Takeaways:
  1. The Macro Trend: Economic complexity predicts growth better than current GDP. Capital will move toward "high-letter" economies like India and Indonesia.
  2. The Tactical Edge: Prioritize team retention over documentation. Since knowledge is embodied, losing a core team is equivalent to deleting the source code.
  3. The Bottom Line: Success in the next decade belongs to those who treat knowledge as a living network rather than a digital asset.
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December 26, 2025

⚡️GPT5-Codex-Max: Training Agents with Personality, Tools & Trust — Brian Fioca + Bill Chen, OpenAI

Latent Space

AI
Key Takeaways:
  1. The Macro Shift: Agentic Abstraction. We are moving from Model-as-a-Service to Agent-as-a-Service where the harness is as important as the weights.
  2. The Tactical Edge: Standardize your CLI. Use tools like ripgrep (RG) that models already have "habits" for to see immediate performance gains.
  3. The Bottom Line: The next 12 months will see the end of manual integration engineering as agents become capable of navigating UIs and legacy terminals autonomously.
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December 26, 2025

Steve Yegge's Vibe Coding Manifesto: Why Claude Code Isn't It & What Comes After the IDE

Latent Space

AI
Key Takeaways:
  1. The commoditization of syntax means architectural judgment is the only remaining moat. As the cost of code hits zero the value of intent skyrockets.
  2. Replace your manual refactoring workflows with a burn and rebuild strategy. Use agents to generate entirely new modules instead of patching old ones.
  3. Seniority is no longer a shield against obsolescence. You must spend the next six months building your agentic intuition or risk being replaced by a PhD student with a prompt.
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December 28, 2025

One Year of MCP — with David Soria Parria and AAIF leads from OpenAI, Goose, Linux Foundation

Latent Space

AI
Key Takeaways:
  1. The Macro Evolution: Standardized communication layers are replacing custom API integrations. This commoditizes the connector market and moves value to the models that best utilize these tools.
  2. The Tactical Edge: Standardize your internal data tools using MCP servers today. This ensures your company is ready for autonomous agents that can discover and use your resources without manual API integration.
  3. The Bottom Line: The agentic stack is consolidating around MCP. Interoperability is no longer a feature; it is the foundation for the next decade of AI utility.
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December 26, 2025

How Claude Code Works - Jared Zoneraich, PromptLayer

AI Engineer

AI
Key Takeaways:
  1. The transition from Prompt Engineering to Context Engineering where the goal is keeping the model's workspace small and relevant.
  2. Replace your complex classification prompts with a single Bash tool. Let the agent write its own Python scripts to handle data transformations.
  3. The winners in the agent space will not be those with the most complex logic. They will be the ones who build the best tools for the model to use.
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December 26, 2025

Shipping AI That Works: An Evaluation Framework for PMs – Aman Khan, Arize

AI Engineer

AI
Key Takeaways:
  1. The Macro Shift: From Model-Centric to Eval-Centric. The value is moving from the LLM itself to the proprietary evaluation loops that keep the LLM on the rails.
  2. The Tactical Edge: Export production traces and build a "Golden Set" of 50 hard examples. Use these to run A/B tests on every prompt change before hitting production.
  3. The Bottom Line: Reliability is the product. If you cannot measure how your agent fails, you haven't built a product; you've built a demo.
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December 26, 2025

How AI Will Reshape The Economy In 2026 (a16z Big Ideas)

a16z

AI
Key Takeaways:
  1. The transition from passive data storage to active agentic execution across both financial and industrial sectors.
  2. Target unsexy legacy industries like mortgage servicing or rare earth processing where the margin for improvement is highest.
  3. 2026 marks the year where software eating the world moves from the screen to the physical supply chain and the autonomous agent.
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Crypto Podcasts

November 5, 2025

Why the Crypto Markets Seem Down Bad as Bitcoin Dips Below $100K

Unchained

Crypto
Key Takeaways:
  1. Despite the brutal sentiment, both speakers remain bullish, predicting a sharp reversal and a new all-time high for Bitcoin by the end of the year once macro clarity emerges.
  2. Macro is King. Bitcoin's fate is now tied to the broader economy. Forget four-year cycles; the key catalyst is a resolution to the government shutdown, which could unlock pent-up energy in the market.
  3. The Treasury Trade is Toast. The era of companies boosting their stock by simply buying Bitcoin is over. Expect a painful shakeout as the market demands real utility and revenue, leading to more forced selling.
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November 5, 2025

Play to Earn Crypto Games: $65B Opportunity | Open Game Protocol & Zynga Founder

The DCo Podcast

Crypto
Key Takeaways:
  1. Distribution is the prize, not payments. The real money in gaming isn't in payment rails, which are being competed down to zero. The scarcest and most valuable asset is user attention, and Open Game Protocol is designed to monetize distribution.
  2. Decouple to survive. Tying a single game to a single token creates a fatal dependency. A flexible, many-to-many protocol allows ecosystems to thrive by spreading risk and aligning incentives across multiple games and communities.
  3. Content abundance requires new discovery. As AI makes game creation cheap and fast, the bottleneck shifts from production to discovery. Integrating games directly into high-intent surfaces like crypto wallets creates a powerful, non-advertising-based discovery channel.
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November 4, 2025

Bits + Bips LIVE

Unchained

Crypto
Key Takeaways:
  1. **Follow the Suits, Not the Shouts.** The market’s real signal is the massive disconnect between gloomy retail sentiment on social media and the unprecedented optimism from financial advisors and institutional platforms.
  2. **Distribution is the New Kingmaker.** From Ripple buying prime brokerages to Tether leveraging its global south dominance, the primary battle is for distribution channels. The technical "best" solution is irrelevant if it can't reach users.
  3. **Regulation Will Be a Slow Grind, Not a Big Bang.** Comprehensive crypto legislation is politically gridlocked. The industry’s integration into legacy finance will continue brick-by-brick through regulated products like ETFs, not sweeping bills from Congress.
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November 4, 2025

LIVE: BOCCACCIO EXPLAINING TO HIS WIFE THAT THEY LOST IT ALL | 0xResearch

0xResearch

Crypto
Key Takeaways:
  1. Tokenized Funds Are a Real-World Unlock. Unlike many crypto narratives, bringing funds on-chain solves a tangible, expensive problem in traditional finance, creating massive operational efficiencies and new financial primitives.
  2. The Bitcoin Holder Base Is Shifting. The ongoing "Bitcoin IPO" via ETFs means the asset is moving from the hands of early adopters to institutional portfolios. This structural shift will define its future trajectory.
  3. Cash Is Your Best Hedge. In a market with fewer winners, holding cash is a strategic imperative. It prevents forced liquidation and provides the dry powder needed to seize high-conviction opportunities as they arise.
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November 3, 2025

War Stories From a Crypto Founder | Kain Warwick

Empire

Crypto
Key Takeaways:
  1. Airdrops Are Now Protection Money: Stop viewing airdrops as a tool for buying loyalty. The modern meta is about paying the community to prevent negative campaigns. Consider models that require financial commitment, not just clicks.
  2. Decentralization is a Journey, Not a Destination: The path to unseating CEXs is paved with compromises. Prioritize a seamless user experience, even if it means starting with a more centralized architecture, and iterate towards permissionlessness over time.
  3. Surviving is the Ultimate Edge: In a space where most participants wash out after one cycle, consistency is a superpower. The founders and investors who can endure the brutal bear markets and avoid personal burnout are the ones who ultimately win.
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November 3, 2025

“The Debasement Trade” - Luke Gromen on Gold, Bitcoin & The 100 Year Reset

Bankless

Crypto
Key Takeaways:
  1. The Debasement is Permanent. The US fiscal position makes currency debasement a permanent feature, not a bug. The winning strategy is to treat hard assets like gold and Bitcoin as long-term holdings, buying on dips rather than timing a temporary "trade."
  2. Watch Central Banks, Not Pundits. The most significant signal is that foreign central banks are systemically divesting from US Treasuries into gold. This is not market noise; it's a structural realignment of the global financial order.
  3. Own the Physical Asset. Paper gold (like ETFs) carries a critical tail risk. In a true crisis, governments could seize the underlying physical gold and cash-settle ETF holders at a pre-crisis price. If you don't hold it, you don't own it.
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