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AI Podcasts

May 29, 2025

Beyond Leaderboards: LMArena’s Mission to Make AI Reliable

a16z

AI
Key Takeaways:
  1. Reliability Demands Real-Time, Human-Centric Testing: Static benchmarks are dead. AI reliability for complex tasks requires continuous evaluation based on diverse, subjective human preferences in real-world scenarios.
  2. Crowd-Sourced Evaluation Outperforms Insular Expertise: The "wisdom of the crowd," as captured by LMArena, provides a more robust and representative measure of AI performance than siloed expert opinions, preventing narrow value-encoding.
  3. Personalized Evaluation is the Next Frontier: Technologies like "Prompt to Leaderboard" show the potential for highly granular, cost-effective, and personalized AI model selection, maximizing utility for individual users and specific tasks.
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May 28, 2025

Rick Rubin: Vibe Coding is the Punk Rock of Software

a16z

AI
Key Takeaways:
  1. Embrace AI as a Co-Creator: Leverage AI to democratize creation and rapidly iterate, but remember the unique human element—your distinct point of view and intuition—is irreplaceable.
  2. Authenticity Over Algorithm: Whether you're an artist or an entrepreneur, genuine connection comes from unwavering commitment to your core vision, not by chasing fleeting trends or assumed audience desires.
  3. Question Everything, Especially "Answers": Cultivate a mindset of curiosity and critical thinking. AI can provide answers, but true insight comes from deeply engaging with questions and understanding that knowledge is ever-evolving.
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May 27, 2025

7 More Healthy Years: What We Can Learn from Super Agers

a16z

AI
Key Takeaways:
  1. Embrace AI-Powered Prevention: AI's capacity to synthesize vast health data will redefine personalized risk assessment and early intervention, moving us beyond one-size-fits-all healthcare.
  2. Target the "Big Three" Early: Focus on preventing cancer, cardiovascular disease, and neurodegenerative conditions by leveraging their long incubation periods for proactive interventions.
  3. Leverage New Therapeutic Frontiers: Groundbreaking drug classes like GLP-1s and rapid advancements in immunotherapy offer unprecedented tools to combat and, crucially, prevent major diseases.
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May 27, 2025

TAOFU's Mikel & Mitch: Enabling Capital Formation for Subnets on Bittensors $10B+ Network

Delphi Digital

AI
Key Takeaways:
  1. Democratized Subnet Funding: TAOFU’s SNS model allows subnet creators to raise capital without diluting their core emission-earning potential, fostering more shots on goal for AI innovation on Bittensor.
  2. Investor Access & Liquidity: For investors, TAOFU provides a clear mechanism (SNS tokens and an integrated DEX) to invest in early-stage Bittensor subnets and gain liquidity, previously a closed-off and opaque process.
  3. Curated Quality: TAOFU’s permissioned approach and focus on sustainable value capture (with plans for a curator model) aim to filter for high-quality projects, protecting investors while nurturing promising AI ventures within Bittensor.
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May 26, 2025

Has AI Revived the DePIN Sector? | Dmitriy Berenzon

0xResearch

AI
Key Takeaways:
  1. AI is DePIN's Demand Catalyst: The need for affordable AI compute is breathing new life and tangible demand into decentralized infrastructure.
  2. Value Accrual & Revenue are King: For DePIN tokens to thrive in liquid markets, clear mechanisms for value flow-through from opco revenue to the token are non-negotiable; "ARR is the new TVL."
  3. Distribution Trumps Decentralization (for now): Crypto-native solutions, especially in payments, must crack the distribution code or risk being outmaneuvered by Web2 incumbents leveraging their massive user bases.
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May 26, 2025

Chatbot platforms might replace social media

Machine Learning Street Talk

AI
Key Takeaways:
  1. AI Companionship is Exploding: Millions are already deeply engaged with AI for emotional connection, and this is just the beginning as technology like GPT-4o normalizes it.
  2. Lean Engineering Can Win: Chai's success with a tiny, hyper-talented team and innovative techniques like model blending proves that massive VC-backed operations aren't the only path to scale in AI.
  3. The Next Social Platform Might Be AI: As AI offers more active, personalized, and consequence-free social interaction, it could very well become the dominant way people connect, potentially supplanting traditional social media.
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May 25, 2025

How Endless Debt Became America's Culture

Forward Guidance

AI
Key Takeaways:
  1. **Debt is Destiny:** America's fiscal irresponsibility and cultural embrace of debt ensure ongoing money printing and inflation, making currency debasement a near certainty.
  2. **The One True Trade:** Forget complex analytics; the primary goal is preserving purchasing power. This means owning store-of-value assets like Bitcoin and gold, which are positioned to thrive.
  3. **AI Accelerates the Crisis:** Artificial intelligence will not only disrupt labor markets but also intensify the debt crisis by devaluing traditional education and fueling calls for more government relief.
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May 24, 2025

SN85 :: VIDAIO :: Decentralized AI Video Upscaling & Compression ++ Roadmap & Enterprise Utility

Opentensor Foundation

AI
Key Takeaways:
  1. Decentralized AI is Production-Ready: VIDAIO demonstrates that complex AI tasks like video processing can be effectively decentralized and optimized through BitTensor's subnet model, with miners already outperforming base models.
  2. Perceptual Quality Wins: Focusing on human-perceived video quality, rather than just raw specs, is key for AI video tools, leading to more efficient and visually appealing results.
  3. Subnets Must Aim for Self-Sufficiency: The long-term viability of BitTensor subnets hinges on generating real-world revenue and solving actual customer problems, moving beyond reliance on token emissions.
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May 24, 2025

Sovereign AI: Why Nations Are Building Their Own Models

a16z

AI
Key Takeaways:
  1. National AI is Non-Negotiable: Countries are investing heavily in "AI factories" to control their digital destiny and cultural narratives.
  2. Models are Culture: AI outputs reflect embedded values, making local control over AI development and deployment a geopolitical imperative.
  3. Lead by Building Better: The US can maintain AI leadership by out-innovating competitors and enabling allies, pursuing "foundation model diplomacy" to ensure its technology underpins global progress.
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Crypto Podcasts

July 18, 2025

The Great Ponzi-fication Of Markets | Weekly Roundup

Forward Guidance

Crypto
Key Takeaways:
  1. The Game Is Rigged, Play Accordingly. Traditional analysis is failing. The winning strategy is "grift arbitrage"—investing in assets that benefit from government spending and political connections.
  2. Bonds are Dead, Long Live Yield. With governments committed to fiscal dominance, bonds offer negative real returns. The hunt for yield is driving capital from fiat junk bonds into Bitcoin and Ethereum.
  3. Hedge for the Inevitable Shakeup. The system is fragile. Key risks like aggressive tariffs or a hawkish Bank of Japan could trigger a sharp sell-off. With volatility low, now is the time to buy cheap protection.
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July 19, 2025

Treasury Vehicles, Crypto Bills, 401Ks, and Retail Runups

0xResearch

Crypto
Key Takeaways:
  1. Treasury Vehicles are a Trap. They're the new high-risk, high-reward play, but the danger isn't debt—it's massive shareholder dilution and a rapid, reflexive unwind that will be far quicker and more brutal than Grayscale's.
  2. The Cycle Isn't Dead, It's Rhyming. The market is replaying the classic playbook: BTC runs, ETH surges, and capital spills into retail-favorite alts. Calling a top is a fool's errand, but the exuberance is palpable.
  3. Regulation is a Double-Edged Sword. New laws provide a path for tokens to become commodities but may incentivize projects to launch chains purely for regulatory arbitrage, adding another layer of complexity to the market.
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July 18, 2025

Ethereum’s Comeback, PumpFun’s ICO, and Crypto’s Regulatory Shift | Roundup

Bell Curve

Crypto
Key Takeaways:
  1. **Ethereum's revival is structural, not speculative.** Unprecedented ETF and corporate treasury inflows are creating sustained buying pressure that could push ETH to $10K and beyond, rendering past cynicism obsolete.
  2. **Regulation is the unlock for institutional crypto.** The Clarity and Genius Acts are not just rules; they are the green light for institutional capital that has been waiting on the sidelines for legal certainty.
  3. **The future of consumer crypto is weird and profitable.** Platforms like Pump.fun prove that the most powerful business models may not fit traditional molds but will win by tapping into raw, unfiltered user demand.
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July 18, 2025

ETH Breaks New Records While BTC Hits ANOTHER All Time High

Bankless

Crypto
Key Takeaways:
  1. The ETH Treasury Is The New Institutional Bid. The narrative that powered Bitcoin's run is now being replicated for ETH, but with a twist: former Bitcoin miners are leading the charge, creating a powerful, reflexive buy-cycle.
  2. ETH's Supply Squeeze Is Real. The combination of record ETF demand, minimal proof-of-stake issuance, and a re-staking culture means the buy pressure is overwhelming the available sell-side liquidity.
  3. Regulation Is Becoming A Tailwind. The expected passage of the stablecoin bill provides a legitimate foundation for institutional adoption, turning a long-time headwind into a powerful catalyst for growth.
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July 18, 2025

Breaking Down the PUMP Launch

Lightspeed

Crypto
Key Takeaways:
  1. Solana’s Watershed Moment: The smooth on-chain execution for a high-demand event proved that decentralized infrastructure is not just viable but, in this case, superior to its centralized counterparts.
  2. Value Accrual is Non-Negotiable: The era of valueless governance tokens is over. Protocols must now provide clear, tangible mechanisms like revenue sharing or buybacks to build trust and justify their valuation.
  3. The Real Game is the Front-End: While back-end infrastructure plays are viable, the ultimate prize is owning the user relationship. PUMP’s battle with Axiom for the title of the premier consumer-facing crypto app is the key narrative to watch.
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July 17, 2025

Breaking Down the PUMP Launch | Analyst Round Table

0xResearch

Crypto
Key Takeaways:
  1. On-Chain is the New Main Stage: The Pump launch proved Solana can handle massive retail demand better than established CEXs, a major narrative shift for future token sales.
  2. Brand and Treasury Trump Daily Noise: Pump's $6B+ valuation is driven by its powerful brand and massive war chest. Investors are betting on the long-term picture, not volatile daily metrics.
  3. Value Accrual is Now Table Stakes: The 25% revenue share signals a new era. Protocols can no longer ignore direct value accrual for token holders; it's now a requirement to earn market trust.
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