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AI Podcasts

December 26, 2025

What I learned at the frontier of tech in 2025 (Kelly, Cowen, Wang, Prince)

Azeem Azhar

AI
Key Takeaways:
  1. The Macro Pivot: The transition from weightless software to energy-heavy hardware.
  2. The Tactical Edge: Stop building "wrappers" for model weaknesses.
  3. The Bottom Line: AI value is moving from the model to the grid and the individual reputation.
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December 26, 2025

How AI Will Reshape The Economy In 2026 (a16z Big Ideas)

a16z

AI
Key Takeaways:
  1. The Macro Shift: The Great Re-architecting. As legacy software moats evaporate and industrial supply chains reshore, value is migrating from passive data storage to active execution layers.
  2. The Tactical Edge: Target Archaic Verticals. Identify high-friction industries like mortgage servicing or IT support where the distance between intent and execution is currently measured in days.
  3. The Bottom Line: The next two years will reward those who build systems of action that replace human labor with autonomous agents and software-defined hardware.
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December 27, 2025

Why Scientists Can't Rebuild a Polaroid Camera [César Hidalgo]

Machine Learning Street Talk

AI
Key Takeaways:
  1. The Macro Trend: Economic complexity predicts growth better than current GDP. Capital will move toward "high-letter" economies like India and Indonesia.
  2. The Tactical Edge: Prioritize team retention over documentation. Since knowledge is embodied, losing a core team is equivalent to deleting the source code.
  3. The Bottom Line: Success in the next decade belongs to those who treat knowledge as a living network rather than a digital asset.
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December 26, 2025

⚡️GPT5-Codex-Max: Training Agents with Personality, Tools & Trust — Brian Fioca + Bill Chen, OpenAI

Latent Space

AI
Key Takeaways:
  1. The Macro Shift: Agentic Abstraction. We are moving from Model-as-a-Service to Agent-as-a-Service where the harness is as important as the weights.
  2. The Tactical Edge: Standardize your CLI. Use tools like ripgrep (RG) that models already have "habits" for to see immediate performance gains.
  3. The Bottom Line: The next 12 months will see the end of manual integration engineering as agents become capable of navigating UIs and legacy terminals autonomously.
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December 26, 2025

Steve Yegge's Vibe Coding Manifesto: Why Claude Code Isn't It & What Comes After the IDE

Latent Space

AI
Key Takeaways:
  1. The commoditization of syntax means architectural judgment is the only remaining moat. As the cost of code hits zero the value of intent skyrockets.
  2. Replace your manual refactoring workflows with a burn and rebuild strategy. Use agents to generate entirely new modules instead of patching old ones.
  3. Seniority is no longer a shield against obsolescence. You must spend the next six months building your agentic intuition or risk being replaced by a PhD student with a prompt.
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December 28, 2025

One Year of MCP — with David Soria Parria and AAIF leads from OpenAI, Goose, Linux Foundation

Latent Space

AI
Key Takeaways:
  1. The Macro Evolution: Standardized communication layers are replacing custom API integrations. This commoditizes the connector market and moves value to the models that best utilize these tools.
  2. The Tactical Edge: Standardize your internal data tools using MCP servers today. This ensures your company is ready for autonomous agents that can discover and use your resources without manual API integration.
  3. The Bottom Line: The agentic stack is consolidating around MCP. Interoperability is no longer a feature; it is the foundation for the next decade of AI utility.
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December 26, 2025

How Claude Code Works - Jared Zoneraich, PromptLayer

AI Engineer

AI
Key Takeaways:
  1. The transition from Prompt Engineering to Context Engineering where the goal is keeping the model's workspace small and relevant.
  2. Replace your complex classification prompts with a single Bash tool. Let the agent write its own Python scripts to handle data transformations.
  3. The winners in the agent space will not be those with the most complex logic. They will be the ones who build the best tools for the model to use.
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December 26, 2025

Shipping AI That Works: An Evaluation Framework for PMs – Aman Khan, Arize

AI Engineer

AI
Key Takeaways:
  1. The Macro Shift: From Model-Centric to Eval-Centric. The value is moving from the LLM itself to the proprietary evaluation loops that keep the LLM on the rails.
  2. The Tactical Edge: Export production traces and build a "Golden Set" of 50 hard examples. Use these to run A/B tests on every prompt change before hitting production.
  3. The Bottom Line: Reliability is the product. If you cannot measure how your agent fails, you haven't built a product; you've built a demo.
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December 26, 2025

How AI Will Reshape The Economy In 2026 (a16z Big Ideas)

a16z

AI
Key Takeaways:
  1. The transition from passive data storage to active agentic execution across both financial and industrial sectors.
  2. Target unsexy legacy industries like mortgage servicing or rare earth processing where the margin for improvement is highest.
  3. 2026 marks the year where software eating the world moves from the screen to the physical supply chain and the autonomous agent.
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Crypto Podcasts

November 18, 2025

How Pudgy Penguins Could Become a $1,000,000,000 Brand

The DCo Podcast

Crypto
Key Takeaways:
  1. Value is Decoupling from EBITDA. A brand's true worth is increasingly measured by its cultural impact, not just its revenue. Tokenization provides the mechanism to price and trade this cultural capital.
  2. Memecoins are a Feature, Not a Bug. They are the earliest, purest form of tokenized culture, proving that a financial layer can supercharge a community's growth and alignment.
  3. Invest in Cultural Arbitrage. The biggest opportunities are in projects and brands whose cultural influence dramatically outweighs their current financial metrics. This gap between impact and income is where tokenization creates exponential value.
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November 17, 2025

The Hidden Flaw in Blockchain Design (Dune Analytics)

The DCo Podcast

Crypto
Key Takeaways:
  1. Transparency Is the Best Moderator. Instead of policing content, Dune makes the underlying source code for every analysis public, empowering the community to self-regulate and verify data quality.
  2. Build With the Ethos of the Ecosystem. Dune succeeded by embracing crypto's open-source nature, creating a collaborative platform that felt native to the space, unlike closed-source competitors.
  3. Incentives Don't Have to Be Financial. Reputation, influence, and the ability to contribute to a shared body of knowledge are powerful motivators for community participation in open platforms.
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November 18, 2025

Bitcoin Breaks $95k, Crypto’s Valuation Problem, & The Path To Real On-Chain Users

Empire

Crypto
Key Takeaways:
  1. **Short Everything But Bitcoin.** The vast majority of crypto assets trade at unjustifiable multiples based on cyclical, speculative revenue. Bitcoin, as a "digital gold" macro hedge, is the only asset with a durable investment thesis that stands apart from the overvalued tech plays.
  2. **The L1 Thesis is Dead.** Investing in L1s is a bet on obsolete infrastructure. Future returns will be captured by killer applications that build real businesses and bring non-speculative users on-chain, not by the commoditized blockspace they run on.
  3. **Acquire Users, Don't Wait For Them.** Crypto's central problem is its failure to grow its user base. The winning strategy is to buy existing businesses with real customers and integrate blockchain technology, thereby acquiring distribution rather than trying to build it from scratch in a hyper-competitive market.
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November 14, 2025

State of The Market, Monad's ICO & The Stablecoin Gold Rush | Weekly Roundup

Empire

Crypto
Key Takeaways:
  1. **Corporates are building walled gardens.** Major players are leveraging public chains to create ecosystems they control, launching the "corporate chain meta" where activity is pulled onto proprietary networks like Base.
  2. **Stablecoin M&A is white-hot, but frothy.** The frantic rush to acquire stablecoin infrastructure is driven by stock market optics as much as strategy, echoing the 2017 "add blockchain to your name" craze.
  3. **Capital formation is returning to regulated US platforms.** Monad's ICO on Coinbase, offering zero lockups for US investors, sets a new precedent for compliant token launches and challenges the dominance of offshore exchanges.
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November 14, 2025

Is The Crypto Bull Market Already Over?

Bankless

Crypto
Key Takeaways:
  1. The Fee Switch Is On. Uniswap's pivot to real-yield tokenomics is a watershed moment. Expect other DeFi protocols to follow, finally aligning token value with protocol success and rewarding long-term holders over mercenaries.
  2. Onshore ICOs Are Back. Coinbase’s new token sales platform for US retail is a massive signal that the industry believes the regulatory tide has turned. This could unlock a new wave of capital and mainstream participation.
  3. Privacy Is A High-Stakes Gamble. While the market is rewarding privacy tokens, the 5-year prison sentence for a wallet developer is a brutal reminder of the risks. Until clear rules are established, building privacy tools in the US remains legally treacherous.
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November 13, 2025

Hash Rate - Ep 144 - SCORE Subnet 44

Hash Rate pod - Bittensor $TAO & Subnets

Crypto
Key Takeaways:
  1. Privacy is Paramount. SCORE’s use of TEEs for a private data track is the key that unlocks enterprise adoption, proving that decentralized networks can handle sensitive information securely.
  2. The 1/10th Price Model Wins. Leveraging Bittensor’s incentive structure allows subnets to radically undercut legacy competitors on price without sacrificing quality, opening up previously inaccessible markets.
  3. Tie Rewards to Revenue. The most sustainable tokenomic model directly links network emissions to real-world cash flow, ensuring the subnet's economy is grounded in tangible business success, not just speculation.
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