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AI Podcasts

December 11, 2025

No Priors Ep. 143 | With ElevenLabs Co-Founder Mati Staniszewski

No Priors: AI, Machine Learning, Tech, & Startups

AI
Key Takeaways:
  1. Strategic Shift: The future of human-computer interaction is voice-first, moving from static content to dynamic, personalized, and agentic experiences.
  2. Builder/Investor Note: Defensibility in AI is increasingly found in deep product layers, specialized architectural breakthroughs (especially in audio), and robust ecosystems, not just raw model scale.
  3. The "So What?": Over the next 6-12 months, expect to see significant advancements in proactive AI agents, immersive media, and personalized education, with voice as the core interface.
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December 10, 2025

The Unicorn Founder Who Delegated Everything.

a16z

AI
Key Takeaways:
  1. The AI-Delegation Revolution is Here: Start experimenting with AI tools like ChatGPT for delegation now. The future involves proactive machine assistants deeply integrated into your workflow.
  2. Builders & Investors: Focus on "How to Delegate": The biggest constraint isn't finding assistants, but teaching clients how to delegate effectively. Tools and services that educate delegators will win.
  3. Reclaim Your Ambition: By offloading the mundane, you free up mental bandwidth to think bigger, pursue more ambitious goals, and ultimately, control your most valuable asset: time.
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December 12, 2025

AI Eats the World: Benedict Evans on the Next Platform Shift

a16z

AI
Key Takeaways:
  1. Strategic Implication: The AI bubble is inevitable. Focus on defensible positions: deep product integration, proprietary data, and distribution, rather than just raw model performance.
  2. Builder/Investor Note: The opportunity lies in productizing AI for specific "jobs to be done" within niche industries, creating intuitive UIs, and building in validation, not just building another foundational model.
  3. The "So What?": We're about to figure out the true "job to be done" for many industries. AI will unbundle existing businesses by exposing their hidden inefficiencies or non-obvious defensibilities.
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December 13, 2025

The Mathematical Foundations of Intelligence [Professor Yi Ma]

Machine Learning Street Talk

AI
Key Takeaways:
  1. Embrace Parsimony and Self-Consistency: Adopt these principles as guiding forces in AI design. Build models that not only compress data efficiently but also maintain a high degree of self-consistency to ensure accurate and reliable world models.
  2. Focus on Abstraction, Not Just Memorization: Prioritize developing systems that can abstract knowledge beyond mere memorization. Move beyond surface-level compression and aim for models that can discover and reason about the underlying principles of the world.
  3. Understand and Reproduce the Brain’s Mechanisms: Focus on understanding and reproducing the mechanisms in the human brain that enable deductive reasoning, logical thinking, and the creation of new scientific theories to truly push AI to the next level.
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December 10, 2025

Nav Kumar: Trishool, AI Alignment, Subnet 23, Mechanistic Interpretability, Rogue LLMs | Ep. 75

Ventura Labs

AI
Key Takeaways:
  1. **Prioritize AI Safety Research:** Invest aggressively in understanding and mitigating AI risks to safeguard humanity against potential rogue LLMs.
  2. **Support Decentralized AI Alignment:** Champion decentralized platforms like Bit Tensor and initiatives like Trishool that promote open and transparent AI alignment research.
  3. **Embrace Mechanistic Interpretability:** Drive the development of tools that enable us to understand and control the internal workings of AI models, ensuring alignment with human values.
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December 10, 2025

Everyone Needs an Assistant. Here’s Why.

a16z

AI
Key Takeaways:
  1. Embrace Delegation as a Foundational Skill: Whether you leverage AI or human support, mastering delegation is paramount for unlocking personal and professional potential.
  2. Prioritize Time Ownership: Recognize time as your most valuable asset and design your life and calendar around your highest goals.
  3. Start Small, Scale Intentionally: Begin with affordable AI tools and gradually incorporate human assistance as your budget and needs evolve, building trust and compounding leverage over time.
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December 8, 2025

Building The Chip That Could Unlock AGI | Naveen Rao

a16z

AI
Key Takeaways:
  1. **Embrace Analog:** Explore and invest in analog computing solutions to overcome the energy limitations of current digital AI systems.
  2. **Prioritize Causality:** Shift focus towards AI models that incorporate time and causality, potentially unlocking more advanced and human-like intelligence.
  3. **Support Hardware Innovation:** Invest in and foster startups like Unconventional AI that are tackling fundamental challenges in AI hardware.
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December 8, 2025

Why AI Will Have To Run On Blockchains

The DCo Podcast

AI
Key Takeaways:
  1. Blockchain is essential for AI to ensure censorship resistance and uninterrupted accessibility.
  2. Trustworthy AI agents require on-chain governance to manage assets securely and transparently.
  3. AI agents can drastically accelerate blockchain adoption and optimize corporate processes.
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December 7, 2025

Tensor Logic "Unifies" AI Paradigms [Pedro Domingos]

Machine Learning Street Talk

AI
Key Takeaways:
  1. Tensor Logic provides a unified framework for AI, bridging the gap between symbolic AI and deep learning, offering improved reasoning, transparency, and efficiency.
  2. The language addresses the limitations of current AI systems, enabling reliable deduction and facilitating structure learning through gradient descent, paving the way for more interpretable and controllable AI.
  3. Tensor Logic has the potential to advance AI education by providing a single language for teaching the entire gamut of AI. Its gradual adoption path allows developers to integrate it into existing workflows.
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Crypto Podcasts

November 29, 2025

In Defense of Exponentials – Haseeb Reads His Viral Essay – The Chopping Block

Unchained

Crypto
Key Takeaways:
  1. **Stop Applying Linear Valuations to Exponential Tech.** Judging Ethereum on its P/E ratio is like criticizing Amazon in 1999 for its lack of profits. It’s a category error. Value chains based on their probability of capturing a piece of a future trillion-dollar system.
  2. **The Prize Is Worth Winning.** The entire investment case for new L1s hinges on the belief that incumbents like Ethereum and Solana are immensely valuable. If they are, then a small probability of becoming the next one justifies a multi-billion dollar valuation today.
  3. **Zoom Out and Believe.** The current market is trapped in short-term cynicism. The real alpha comes from adopting a Silicon Valley mindset over a Wall Street one, recognizing that you are living through a technological revolution on par with the early internet.
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November 28, 2025

Can ‘Choose Rich’ Nick Create the Barstool Sports of Crypto?

Unchained

Crypto
Key Takeaways:
  1. Weaponize cringe for distribution. The ‘Choose Rich Nick’ model proves that being the butt of the joke is a powerful growth hack. Manufacturing moments that invite mockery creates a viral loop of outrage and engagement that funnels attention to the core business.
  2. Authenticity is a liability. The most successful stunts are meticulously planned fabrications. From fake girlfriends to staged yacht expulsions, the goal isn't to be real but to create a compelling narrative that the internet can’t ignore.
  3. Success hinges on ambiguity. The content is designed to polarize. Its virality depends on a split audience: one half gets the joke and celebrates the performance, while the other half takes it at face value, fueling the outrage machine that drives impressions.
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November 28, 2025

Klarna Launches A Stablecoin, Hyperliquid Perps & The Prediction Market Wars | Weekly Roundup

Empire

Crypto
Key Takeaways:
  1. Fintech is the New On-Ramp. Giants like Klarna are adopting stablecoins for economic utility, not speculation. This signals a new wave of adoption driven by real-world efficiency gains.
  2. Re-evaluate Your Valuations. The massive valuation gap between a fintech like Klarna and an L1 like Solana forces a critical question: will value accrue to the rails or the businesses that use them to serve hundreds of millions of customers?
  3. Distribution is Undefeated. Robinhood’s move to sideline its partner Kalshi proves that owning the customer relationship is the ultimate moat, a crucial lesson for infrastructure projects reliant on third-party distribution.
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November 27, 2025

Anthony Sassano on Why This Cycle Isn’t Playing Out Like the Last Ones

Bankless

Crypto
Key Takeaways:
  1. The Old Playbooks Are Obsolete. This isn't your 2021 bull run. The four-year cycle is broken, institutional flows have altered market dynamics, and historical patterns are no longer reliable predictors of future performance.
  2. Ethereum Is Entering Hyper-Scale. A relentless upgrade cadence is simultaneously scaling both L1 (via gas limit increases) and L2s (via blob scaling), even before the ZK revolution delivers another 100x+ throughput boost to the mainnet.
  3. Adaptability Is the Ultimate Security. Existential threats like quantum computing are moving from science fiction to near-term reality. Ethereum's culture of continuous improvement is its greatest defense, while chains resistant to change face a brewing crisis.
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November 25, 2025

Closed my ETH Short ($578k Profit). What’s Next for Crypto?

Taiki Maeda

Crypto
Key Takeaways:
  1. **ETH is Overvalued and Avoidable.** Its fundamentals do not justify its sky-high valuation. View it as a flawed asset, not a mandatory portfolio holding for crypto investors.
  2. **Farm, Don't Trade.** The most reliable retail edge isn't trading, but airdrop farming. It allows you to acquire assets from overvalued launches without providing exit liquidity.
  3. **Cash is a Position.** In a market defined by negative reflexivity and dwindling liquidity, the winning strategy is capital preservation. Avoid the casino, raise cash, and wait for the market to present clear, undervalued opportunities.
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November 24, 2025

How to Trade Crypto Cycles with Raoul Pal

Empire

Crypto
Key Takeaways:
  1. Stop Obsessing Over the Halving. The four-year cycle is a narrative, not a driver. The real signal is the macro business cycle, driven by debt refinancing and central bank liquidity. Track the ISM index: historically, buying below 50 and selling above 57 has been a winning strategy.
  2. Invest in Networks, Not Spreadsheets. Value crypto protocols based on network effects (active users and transaction value), not discounted cash flows. The long-term bet is on the growth of the network itself, as this is where wealth has compounded most dramatically.
  3. Survive to Compound. Structure your portfolio to withstand volatility. Have external cash flow so you’re never a forced seller, and take "lifestyle chips" off the table during rallies to manage psychological stress. Drawdowns are a feature, not a bug—use them to add to your long-term positions.
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