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AI Podcasts

May 29, 2025

Beyond Leaderboards: LMArena’s Mission to Make AI Reliable

a16z

AI
Key Takeaways:
  1. Reliability Demands Real-Time, Human-Centric Testing: Static benchmarks are dead. AI reliability for complex tasks requires continuous evaluation based on diverse, subjective human preferences in real-world scenarios.
  2. Crowd-Sourced Evaluation Outperforms Insular Expertise: The "wisdom of the crowd," as captured by LMArena, provides a more robust and representative measure of AI performance than siloed expert opinions, preventing narrow value-encoding.
  3. Personalized Evaluation is the Next Frontier: Technologies like "Prompt to Leaderboard" show the potential for highly granular, cost-effective, and personalized AI model selection, maximizing utility for individual users and specific tasks.
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May 28, 2025

Rick Rubin: Vibe Coding is the Punk Rock of Software

a16z

AI
Key Takeaways:
  1. Embrace AI as a Co-Creator: Leverage AI to democratize creation and rapidly iterate, but remember the unique human element—your distinct point of view and intuition—is irreplaceable.
  2. Authenticity Over Algorithm: Whether you're an artist or an entrepreneur, genuine connection comes from unwavering commitment to your core vision, not by chasing fleeting trends or assumed audience desires.
  3. Question Everything, Especially "Answers": Cultivate a mindset of curiosity and critical thinking. AI can provide answers, but true insight comes from deeply engaging with questions and understanding that knowledge is ever-evolving.
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May 27, 2025

7 More Healthy Years: What We Can Learn from Super Agers

a16z

AI
Key Takeaways:
  1. Embrace AI-Powered Prevention: AI's capacity to synthesize vast health data will redefine personalized risk assessment and early intervention, moving us beyond one-size-fits-all healthcare.
  2. Target the "Big Three" Early: Focus on preventing cancer, cardiovascular disease, and neurodegenerative conditions by leveraging their long incubation periods for proactive interventions.
  3. Leverage New Therapeutic Frontiers: Groundbreaking drug classes like GLP-1s and rapid advancements in immunotherapy offer unprecedented tools to combat and, crucially, prevent major diseases.
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May 27, 2025

TAOFU's Mikel & Mitch: Enabling Capital Formation for Subnets on Bittensors $10B+ Network

Delphi Digital

AI
Key Takeaways:
  1. Democratized Subnet Funding: TAOFU’s SNS model allows subnet creators to raise capital without diluting their core emission-earning potential, fostering more shots on goal for AI innovation on Bittensor.
  2. Investor Access & Liquidity: For investors, TAOFU provides a clear mechanism (SNS tokens and an integrated DEX) to invest in early-stage Bittensor subnets and gain liquidity, previously a closed-off and opaque process.
  3. Curated Quality: TAOFU’s permissioned approach and focus on sustainable value capture (with plans for a curator model) aim to filter for high-quality projects, protecting investors while nurturing promising AI ventures within Bittensor.
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May 26, 2025

Has AI Revived the DePIN Sector? | Dmitriy Berenzon

0xResearch

AI
Key Takeaways:
  1. AI is DePIN's Demand Catalyst: The need for affordable AI compute is breathing new life and tangible demand into decentralized infrastructure.
  2. Value Accrual & Revenue are King: For DePIN tokens to thrive in liquid markets, clear mechanisms for value flow-through from opco revenue to the token are non-negotiable; "ARR is the new TVL."
  3. Distribution Trumps Decentralization (for now): Crypto-native solutions, especially in payments, must crack the distribution code or risk being outmaneuvered by Web2 incumbents leveraging their massive user bases.
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May 26, 2025

Chatbot platforms might replace social media

Machine Learning Street Talk

AI
Key Takeaways:
  1. AI Companionship is Exploding: Millions are already deeply engaged with AI for emotional connection, and this is just the beginning as technology like GPT-4o normalizes it.
  2. Lean Engineering Can Win: Chai's success with a tiny, hyper-talented team and innovative techniques like model blending proves that massive VC-backed operations aren't the only path to scale in AI.
  3. The Next Social Platform Might Be AI: As AI offers more active, personalized, and consequence-free social interaction, it could very well become the dominant way people connect, potentially supplanting traditional social media.
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May 25, 2025

How Endless Debt Became America's Culture

Forward Guidance

AI
Key Takeaways:
  1. **Debt is Destiny:** America's fiscal irresponsibility and cultural embrace of debt ensure ongoing money printing and inflation, making currency debasement a near certainty.
  2. **The One True Trade:** Forget complex analytics; the primary goal is preserving purchasing power. This means owning store-of-value assets like Bitcoin and gold, which are positioned to thrive.
  3. **AI Accelerates the Crisis:** Artificial intelligence will not only disrupt labor markets but also intensify the debt crisis by devaluing traditional education and fueling calls for more government relief.
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May 24, 2025

SN85 :: VIDAIO :: Decentralized AI Video Upscaling & Compression ++ Roadmap & Enterprise Utility

Opentensor Foundation

AI
Key Takeaways:
  1. Decentralized AI is Production-Ready: VIDAIO demonstrates that complex AI tasks like video processing can be effectively decentralized and optimized through BitTensor's subnet model, with miners already outperforming base models.
  2. Perceptual Quality Wins: Focusing on human-perceived video quality, rather than just raw specs, is key for AI video tools, leading to more efficient and visually appealing results.
  3. Subnets Must Aim for Self-Sufficiency: The long-term viability of BitTensor subnets hinges on generating real-world revenue and solving actual customer problems, moving beyond reliance on token emissions.
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May 24, 2025

Sovereign AI: Why Nations Are Building Their Own Models

a16z

AI
Key Takeaways:
  1. National AI is Non-Negotiable: Countries are investing heavily in "AI factories" to control their digital destiny and cultural narratives.
  2. Models are Culture: AI outputs reflect embedded values, making local control over AI development and deployment a geopolitical imperative.
  3. Lead by Building Better: The US can maintain AI leadership by out-innovating competitors and enabling allies, pursuing "foundation model diplomacy" to ensure its technology underpins global progress.
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Crypto Podcasts

August 20, 2025

Crypto Credit Markets Will Rewrite Risk Management | David Grider

Forward Guidance

Crypto
Key Takeaways:
  1. **Alpha Is Now Risk Management:** In a maturing crypto market, outperformance comes from actively managing gross exposure and utilizing a diverse strategy mix (equities, credit, derivatives), not just holding beta.
  2. **Crypto Credit Offers Unprecedented Asymmetry:** Instruments like convertible bonds on DATs provide credit-like downside protection while retaining crypto-like upside, creating a compelling opportunity for risk-adjusted returns that is often cheaper than replicating with native options.
  3. **The DAT Playbook Is Evolving:** The next cycle’s drama won't just be about token prices. Watch for DATs using leverage, building out their own "yield curves," and the eventual distressed cycle where activists and acquirers step in to capture NAV discounts.
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August 18, 2025

One More Push Higher Before the Crash?

1000x Podcast

Crypto
Key Takeaways:
  1. The ETH Rally is an Illusion. Price action is dictated by treasury company flows, not fundamentals. Monitor their stock premium/discount to NAV as a leading indicator for the market top.
  2. Prepare for a "Stupid" Finale. The market is primed for one last FOMO-driven blow-off top. This is the signal to sell into strength, not add risk.
  3. Set Up the Next Home Run. The inevitable crash of treasury company stocks will present a massive opportunity. Prepare to buy these assets at deep discounts (30%+) to NAV when the market panics.
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August 18, 2025

What Liquid Funds Are Buying

Empire

Crypto
Key Takeaways:
  1. Concentrated Bets on Fundamentals Win. The era of "spray and pray" is over. The new meta is building highly concentrated portfolios (10-15 tokens) based on deep fundamental analysis of protocols with clear revenue models and product-market fit.
  2. Digital Asset Treasuries Are TradFi's On-Ramp. DATs are more than a short-term trade; they are the primary bridge for institutional capital to gain crypto exposure. Their marketing power is proving to be as crucial as their financial engineering.
  3. The 24/7 Market Is Coming. The tokenization of equities isn't a matter of *if* but *when*. This shift will create a fiduciary obligation for funds to move to on-chain assets, forcing a rapid, systemic evolution of financial markets.
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August 16, 2025

Why DATs Beyond BTC And ETH Are Risky

Empire

Crypto
Key Takeaways:
  1. **Concentrate on the Winners:** Bitcoin is the established store-of-value asset, and Ethereum is the dominant settlement layer for high-value digital assets. The data shows they have already won their respective categories.
  2. **The Rest is a Long Tail of Risk:** Investing outside of Bitcoin and Ethereum is a bet against powerful, gravity-like market forces. These alternatives are competing for a sliver of the market, increasing their risk of becoming obsolete.
  3. **Power Law is the Rule:** The market isn't about finding the "next" Ethereum; it's about recognizing that power laws are creating a duopoly where the vast majority of value will continue to accrue to the top two assets.
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August 16, 2025

Can ETH Keep Pumping Or Is It All Over?!

Steady Lads Podcast

Crypto
Key Takeaways:
  1. The New Game is Financial Engineering. The market's primary driver is the "Digital Asset Treasury" meta. Bitcoin leverages its "pristine collateral" narrative for debt financing, while Ethereum leverages native yield to justify its premium.
  2. Don't Expect a 2021 Redux. The institutional capital fueling this rally is not here to bid on your favorite altcoin. Their focus is on BTC, ETH, and treasury-related arbitrage, making a widespread, retail-driven altcoin season unlikely.
  3. De-Risk and Secure Profits. After a 3x run, seasoned traders are taking profits on ETH. The consensus is to refuse to round-trip your gains, pay down on-chain debt, and shift to scalping volatility rather than betting on a continued parabolic advance.
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August 15, 2025

The Best of Bell Curve

Bell Curve

Crypto
Key Takeaways:
  1. **Execution Guarantees Trump EVM Compatibility:** For complex financial products like derivatives, the ability to mathematically prove solvency outweighs the benefits of EVM compatibility, driving the rise of purpose-built L1s.
  2. **Memecoins Are a Macro Indicator:** Don't dismiss memecoins as a distraction. They are a direct, high-beta response to monetary debasement, signaling retail's desperation for returns in a broken financial system.
  3. **The Consumer War Is On:** While Ethereum solidifies its hold on institutional finance, the battle for consumer attention is just beginning. The success of its coordinated L2 strategy will determine if it can reclaim the narrative from chains like Solana.
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