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AI Podcasts

August 21, 2025

Can AI Fix Housing and Healthcare Affordability?

a16z

AI
Key Takeaways:
  1. AI is the deflationary force for stagnant sectors. While software ate the world, it skipped housing and healthcare. AI is finally tackling the operational drag that has caused costs to balloon for decades.
  2. To solve the housing crisis, make it profitable. The path to more housing supply runs through better returns. By making property operations radically more efficient, AI attracts the capital required to build.
  3. The future of work is human + AI. Automation won't eliminate jobs; it will transform them. As AI handles the administrative grind, human roles will shift to higher-value work like community engagement and complex problem-solving.
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August 19, 2025

Hash Rate - Ep 129 - Macrocosmos IOTA (sn9) and DataUniverse (sn13)

Hash Rate pod - Bitcoin, AI, DePIN, DeFi

AI
Key Takeaways:
  1. DTO Means Business: Dynamic TAO has forced a Darwinian shift. Subnets must now achieve product-market fit and generate real revenue to survive, transforming from research projects into self-sustaining businesses.
  2. IOTA’s Grand Ambition: IOTA (SN9) isn't just another model trainer; its architecture aims to train trillion-parameter models on decentralized, consumer-grade hardware, directly challenging the dominance of centralized AI labs.
  3. Time to Garden: The protocol's long-term health hinges on active governance. A strong sentiment is emerging to prune low-effort or malicious subnets to focus emissions on projects capable of creating real, lasting value.
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August 19, 2025

Hash Rate - Ep 128 - Ridges ($TAO Subnet 62)

Hash Rate pod - Bitcoin, AI, DePIN, DeFi

AI
Key Takeaways:
  1. AI Is Moving from Copilot to Pilot. Ridges is betting that the future isn't AI assisting humans, but AI replacing them for specific tasks. Their goal is to make hiring a software engineer as simple as subscribing to a service.
  2. Decentralized Economics Are a Moat. By leveraging Bittensor's incentive layer, Ridges outsources a $15M/year R&D budget to a global pool of competing developers, achieving a cost structure and innovation velocity that centralized players cannot match.
  3. The Breakout Subnet Is Coming. Ridges showcases how a Bittensor subnet can solve real-world business problems—privacy, cost, and quality degradation—to build a product that is not just cheaper, but fundamentally better than its centralized counterparts.
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August 18, 2025

Dylan Patel on GPT-5’s Router Moment, GPUs vs TPUs, Monetization

a16z

AI
Key Takeaways:
  1. From Performance to Profit: The AI industry is pivoting from a war of benchmarks to a game of unit economics. Features like GPT-5’s router signal that cost management and monetization are now as important as model capabilities.
  2. Hardware is a Supply Chain Game: Nvidia’s true moat is its end-to-end control of the supply chain. Competitors aren't just fighting a chip architecture; they're fighting a logistical behemoth that consistently out-executes on everything from memory procurement to time-to-market.
  3. The Grid is the Limit: The biggest check on AI’s expansion is the physical world. The speed at which new power infrastructure and data centers can be built will dictate the pace of AI deployment in the US, creating a major advantage for those who can build faster.
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August 18, 2025

Subnet 56 :: Gradients :: Bittensor End-to-end AI Model Training Suite

Opentensor Foundation

AI
Key Takeaways:
  1. Performance is Proven, Not Promised. Gradients isn't just making claims; it’s delivering benchmark-crushing results, consistently outperforming centralized incumbents and producing state-of-the-art models.
  2. Open Source Unlocks the Enterprise. The shift to verifiable, open-source training scripts is a direct solution to customer data privacy concerns, turning a critical vulnerability into a competitive advantage.
  3. The AutoML Flywheel is Spinning. The network's competitive, tournament-style mechanism creates a self-optimizing system that continuously aggregates the best training techniques, ensuring it remains at the cutting edge.
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August 16, 2025

Google DeepMind Lead Researchers on Genie 3 & the Future of World-Building

a16z

AI
Key Takeaways:
  1. **World Models Are a New Modality.** Genie 3 is not just better video; it's an interactive environment generator. This divergence from passive, cinematic models like Veo signals a new frontier focused on agency and simulation, creating a distinct discipline within generative AI.
  2. **Simulation Is the Key to Embodied AI.** The biggest hurdle for robotics is the lack of realistic training environments. Genie 3 tackles this "sim-to-real" gap head-on, providing a scalable way to train agents on infinite experiences before they ever touch physical hardware.
  3. **Emergent Properties Will Drive the Future.** Key features like spatial memory and nuanced physics weren't explicitly coded but emerged from scaling. The next breakthroughs in world models will come from discovering these unexpected capabilities, not just refining existing ones.
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August 15, 2025

Greg Brockman on OpenAI's Road to AGI

Latent Space

AI
Key Takeaways:
  1. AGI is a Compute Game. The primary bottleneck is compute. The process is one of "crystallizing" energy into compute, then into the potential energy of a trained model. More compute means more intelligence.
  2. The Future is a "Manager of Models." AGI won't be a single entity. It will be an orchestrator that delegates tasks to a fleet of specialized models, from fast local agents to powerful cloud reasoners.
  3. Build for Your AI Coworker. To maximize leverage, structure codebases for AI. This means self-contained modules, robust unit tests, and clear documentation—treating the AI as a team member, not just a tool.
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August 15, 2025

Novelty Search August 14, 2025

taostats

AI
Key Takeaways:
  1. Performance is a Solved Problem. For post-training tasks, Gradients has established itself as the best in the world. Developers should stop writing custom training loops and leverage the platform to achieve superior results faster and cheaper.
  2. Open Source Unlocks Trust and Revenue. The pivot to open source directly addresses the biggest enterprise adoption hurdle—data privacy. This move positions Gradients to capture significant market share and drive real revenue to the subnet.
  3. The Bittensor Flywheel is Real. Gradients didn't just beat a major AI lab; its incentive mechanism ensures it will continue to improve at a pace traditional companies cannot match. Miners who don’t innovate are automatically replaced, creating a relentless drive toward optimization.
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August 15, 2025

Subnet 56 :: Gradients :: Bittensor End-to-end AI Model Training Suite

Opentensor Foundation

AI
Key Takeaways:
  1. **Training is a Solved Problem.** For users and developers, the message is clear: stop building custom training loops. Gradients offers superior performance out-of-the-box, turning the complex art of model training into a simple API call.
  2. **Open Source is the Ultimate Competitive Moat.** By making top training scripts public, Gradients accelerates its own innovation flywheel, creating a continuously compounding advantage that closed-source competitors cannot replicate.
  3. **The Best 8B Model is Now from Bittensor.** Gradients has moved beyond theoretical benchmarks to produce a state-of-the-art model that beats a leading industry player. This is a powerful proof-of-concept for the entire Bittensor ecosystem.
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Crypto Podcasts

December 30, 2025

Landmark Regulation, ICOs, Downtober & Privacy: 2025 Crypto Year in Review (Part 2)

Unchained

Crypto
Key Takeaways:
  1. The Macro Shift: Regulatory moats are being built around stablecoins to protect bank deposits. This forces a migration toward "consortium" models like Stripe’s Tempo.
  2. The Tactical Edge: Audit market maker agreements to ensure protection against exchange API failures. Reliability is now a competitive advantage.
  3. 2026 looks like a liquidity-driven recovery. The "easy road" is over, but the infrastructure for the next cycle is finally being built by adults.
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December 29, 2025

HIP-3 and Markets by Kinetiq with Omnia | Livestream

0xResearch

Crypto
Key Takeaways:
  1. The Macro Trend: Vertical Integration. Protocols are moving from single-utility tools to full-stack financial ecosystems that own both the liquidity and the application layer.
  2. The Tactical Edge: Monitor HIP-3 auctions. Watch how new exchanges utilize Kinetic's infrastructure to bootstrap liquidity without issuing predatory new tokens.
  3. The Bottom Line: Kinetic is building the infrastructure for a post-Binance world where users own the venues they trade on. This matters for your roadmap because user-owned liquidity is the next major phase of DeFi growth.
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December 29, 2025

Investing Trends for 2026: DeFi, Tokenization, Capital Formation, Speculation & AI

Bankless

Crypto
Key Takeaways:
  1. The move from human-centric trading to an agent-led economy where programmable money is the native substrate.
  2. Prioritize startups building verticalized tokenization for high-yield exogenous assets rather than generalized service providers.
  3. Crypto is becoming the invisible backend for global finance. Over the next year, the winners will be those who hide the blockchain while using its efficiency to crush traditional margins.
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December 28, 2025

Getting To The Bottom Of Quantum w/ Rearden

The Gwart Show

Crypto
Key Takeaways:
  1. The Macro Transition: Cryptographic security is moving from static models to active systems that must anticipate both classical and quantum breakthroughs.
  2. The Tactical Edge: Audit your UTXOs to ensure no address reuse and keep your Xpubs strictly offline.
  3. The Bottom Line: Quantum risk is a long tail event that serves as a catalyst for necessary Bitcoin upgrades like OP_CAT and BIP 360.
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December 28, 2025

Getting To The Bottom Of Quantum w/ Rearden

The Gwart Show

Crypto
Key Takeaways:
  1. The Macro Shift: Technical reality is decoupled from venture capital hype.
  2. The Tactical Edge: Use hashed addresses and run a node.
  3. The Bottom Line: Quantum is an engineering hurdle rather than an existential crisis for the next decade.
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December 28, 2025

What Can DeFi Users Actually Do on Canton Network Today?

The DCo Podcast

Crypto
Key Takeaways:
  1. The Macro Shift: Institutional Migration. As large-scale capital seeks on-chain efficiency, it will gravitate toward networks that offer privacy as a default.
  2. The Tactical Edge: Monitor Infrastructure. Track the rollout of Canton-native stablecoins to identify when the liquidity floodgates open for professional traders.
  3. The Bottom Line: Canton is building for the "Quiet Money." If you are looking for the next dog coin, look elsewhere, but if you want to see how the global financial system actually moves on-chain, this is the network to watch over the next year.
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