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AI Podcasts

November 17, 2025

Hash Rate - Ep 145 - TAO Subnets Templar (3), Basilica (39), Grail (81)

Hash Rate pod - Bittensor $TAO & Subnets

AI
Key Takeaways:
  1. **A New Market is Born:** Templar isn't just cheaper; it enables something that was previously impossible for 99% of the world. Democratizing pre-training means anyone can build a truly custom, sovereign AI.
  2. **Productization is Underway:** Covenant is no longer just a research project. With enterprise sales in motion, the focus is now on revenue. The team has committed that 100% of fees from custom training will be used to buy back its tokens.
  3. **Economics are Being Rewritten:** Basilica’s incentive mechanism is a direct critique of unsustainable models on other compute subnets. Its focus on profitability and positive TAO flow sets a new standard for economic design on Bittensor.
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November 17, 2025

Bryan Johnson: Don’t Die, Beating Entropy, AI Alignment & The Two-Species Future

Bankless

AI
Key Takeaways:
  1. AI Forces a Moral Reboot. The emergence of superintelligence renders our current societal goals dangerously obsolete. Survival must become the new prime directive.
  2. Existence is a Team Sport. The "Don't Die" philosophy is a collective mission ("we don't die") to ensure species-wide survival, not a selfish quest for individual immortality.
  3. Prepare for the Biological Sandbox. Humanity is moving from manipulating physical atoms and digital bits to programming our own biology—a frontier with both unimaginable potential and catastrophic risk.
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November 17, 2025

Emmett Shear on Building AI That Actually Cares: Beyond Control and Steering

a16z

AI
Key Takeaways:
  1. Stop Trying to “Steer” AGI. The control paradigm is a dead end. The goal isn’t a more obedient tool; it’s a trustworthy teammate. We must shift from engineering control to cultivating care.
  2. Alignment is a Process, Not a Product. True alignment isn't a fixed set of rules. It’s a dynamic process of moral learning, akin to raising a child. AIs that only follow rules are brittle and dangerous.
  3. Build for Cooperation, Not Command. The technical path forward involves training AIs in rich, multi-agent environments where they must learn cooperation and theory of mind—the foundational skills for becoming a good member of a group.
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November 16, 2025

Rawson Haverty presents "US & China AI: Lessons from Across the Pacific" | dAGI Summit 2025

Delphi Digital

AI
Key Takeaways:
  1. US Leads in Capital-Intensive Frontier AI; China Excels at Industrial Diffusion. The US leverages deep capital markets for its massive compute buildout and AGI research, while China uses state direction to embed AI into its vast industrial base via open-source models and hardware.
  2. Market Structure Dictates AI Strategy. The US "efficient oligopoly" model prioritizes global dominance and profit reinvestment by a few players. China's "subjugated swarm" model creates intense domestic competition, driving down prices and accelerating adoption at the cost of profitability.
  3. Geopolitical Tension May Be a Necessary Stabilizer. The competition between the US's freedom-oriented, frontier-pushing approach and China's stability-focused, diffusion-driven model creates a complementary tension that could be essential for navigating the "narrow corridor" between AI-driven totalitarianism and uncontrollable chaos.
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November 13, 2025

How Will AI Change Gaming Development? (A Dev’s Take)

The DCo Podcast

AI
Key Takeaways:
  1. Development timelines are collapsing from months to days. AI allows developers to swap entire asset libraries or generate new game concepts at unprecedented speed, turning a two-month art project into a day's work.
  2. The lifespan of any single game is shrinking. Prepare for a world of disposable entertainment. As AI floods the market with content, the strategy will pivot from creating one long-lasting hit to deploying a rapid succession of engaging experiences.
  3. Games are the next evolution of the attention economy. Just as memes became a core tool for community-building around tokens, easily created games will be the next engine for capturing and directing user attention in a hyper-competitive digital world.
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November 11, 2025

AI Nerves, Crypto Realism, Privacy Coins, & Lessons From Trading

1000x Podcast

AI
Key Takeaways:
  1. Adopt a Stock Picker's Mentality. The crypto market is no longer a monolith where a rising tide lifts all boats. Focus on assets with real products, user growth, and cash flow, as the gap between winners and losers will only widen.
  2. Shorting is a Tactical Assault, Not a Siege. Don't "invest" in a short. The only viable short strategies are tactical, targeting specific events like VC unlocks or news-driven spikes. Otherwise, even "total scams" can 5x against you.
  3. Cultivate a Goldfish's Memory. The most critical trading skill is learning how to change your mind. Cut losing trades, forget the loss (but remember the lesson), and redeploy capital without emotional baggage. Stubbornness is a portfolio killer.
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November 11, 2025

Grant Lee: Building Gamma’s AI Presentation Company to 100 Million Users

a16z

AI
Key Takeaways:
  1. Word-of-mouth isn't a feature; it's the engine. Before spending a dime on marketing, obsess over the first 30 seconds of the user experience until people can't help but share it.
  2. Being different is better than being better. Don't build incrementally better slideware. Redefine the core primitives of your category, as Gamma did by moving beyond the 16x9 slide.
  3. Hire painfully slowly to protect your DNA. Resisting the temptation to scale headcount with user growth is a superpower. The goal isn't to hit a hiring target; it's to hire the best people.
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November 7, 2025

Amjad Masad & Adam D’Angelo: How Far Are We From AGI?

a16z

AI
Key Takeaways:
  1. AGI Is a Definitional Debate. Progress toward an AI that can replace a remote worker is happening fast. However, achieving "true" human-like learning efficiency may require an entirely new paradigm beyond scaling current LLMs.
  2. The New Creator Economy Is Code. AI is turning software development into a mainstream creative pursuit, empowering a new class of solo entrepreneurs who can build what previously required entire teams.
  3. Incumbents Learned Their Lesson. Unlike past tech shifts, today's giants are aggressively adopting AI, making it both a sustaining *and* disruptive force. The market is large enough for both incumbents and startups to create massive value.
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November 6, 2025

Mark Zuckerberg & Priscilla Chan: How AI Will Cure All Disease

a16z

AI
Key Takeaways:
  1. Build the Tools, Not Just the House: CZI’s greatest leverage comes from creating open-source tools and datasets. By building the fundamental infrastructure, they empower the entire scientific community—from academic labs to startups—to accelerate discovery.
  2. Data Is the New Microscope: The future of biology hinges on a tight feedback loop between generating novel, purpose-built datasets and training domain-specific AI models on them. This synergy is unlocking insights that were previously impossible.
  3. Virtual Biology Is the Next Frontier: Simulating biology computationally with "virtual cells" will become the new standard for research, enabling scientists to test riskier hypotheses faster and cheaper, dramatically compressing the timeline for major breakthroughs.
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Crypto Podcasts

February 17, 2026

FTX Changed Finance — Now Institutions Want What Crypto Built

The DCo Podcast

Crypto
Key Takeaways:
  1. Investigate platforms offering regulated perpetual futures on traditional assets. These venues are positioned to capture significant institutional flow by combining crypto's product innovation with TradFi's risk management.
  2. The global financial system is bifurcating, with a clear trend towards regulated, institutional-grade venues for all tradable assets, including novel ones like compute power.
  3. The future of finance involves crypto-native products like perpetuals, but their mass adoption by institutions hinges on robust regulation and superior risk management.
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February 17, 2026

AI Capex Meets SaaS Apocalypse, 18-Month Bear Market & Bitcoin vs Quantum

1000x Podcast

Crypto
Key Takeaways:
  1. The Macro Shift: AI's productivity gains are consolidating power and profits within vertically integrated tech giants, fundamentally altering the competitive landscape for software and infrastructure providers.
  2. The Tactical Edge: Re-evaluate SaaS investments, favoring mega-cap tech companies poised to absorb former SaaS revenues through internal AI-driven development. For crypto, identify and accumulate projects with genuine revenue generation during the bear market.
  3. The Bottom Line: Position your portfolio for a world where AI drives corporate insourcing, crypto valuations reset to fundamentals, and core digital assets like Bitcoin undergo necessary technical upgrades to survive future threats.
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February 17, 2026

VVV, CFTC and Morpho | Livestream

0xResearch

Crypto
Key Takeaways:
  1. Traditional finance is integrating with crypto, but often on its own terms, demanding more transparency from protocols while VCs continue to deploy significant capital into specific, high-potential crypto and AI intersections.
  2. Scrutinize institutional "partnerships" for concrete terms and evaluate protocols based on their true moat against easy forks or platform risk.
  3. The market is bifurcating: clear regulatory wins for specific crypto applications (like prediction markets) and innovative AI/crypto plays are attracting capital, while opaque TradFi deals and general L1 infrastructure face increased scrutiny. Position for clarity and genuine value accrual.
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February 17, 2026

RWA Looping, Crypto Market Structure Bill, & Vaults - Sean Kelley

The Rollup

Crypto
Key Takeaways:
  1. The digitization of finance is accelerating, with institutional capital now actively seeking onchain yield and efficiency. This is creating a competitive pressure cooker for traditional banks, while opening vast opportunities for nimble DeFi protocols.
  2. Focus on protocols building robust RWA infrastructure and those providing deep liquidity for tokenized treasuries. These are the picks and shovels for the coming institutional capital wave.
  3. The fight for stablecoin yield and institutional adoption will define the next 6-12 months. Position yourself to capitalize on the inevitable flow of capital from TradFi to transparent, yield-bearing onchain assets, even if it's just a fraction of the total.
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February 17, 2026

Neo Finance 'N7' Outperforming, Apollo x Morpho, Frax Joins The Show, Bullet Mainnet & Gmoney Calls

The Rollup

Crypto
Key Takeaways:
  1. Explore DeFi protocols in the N7 index (Morpho, Frax, Aave, etc.) for early exposure to institutional capital flows and RWA looping opportunities.
  2. Experiment with AI agents to automate content creation, research, and even software development, drastically cutting operational costs.
  3. The financial system is bifurcating into a "Neo Finance" layer where tokenized real-world assets are integrated with DeFi primitives, and an "AI-augmented" layer where autonomous agents supercharge individual and small team productivity.
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February 16, 2026

Doug Sillard: Taostats, Bittensor Dynamic TAO, Chain Buys, MEV Bots & TaoFlow Explained | Ep. 82

Ventura Labs

Crypto
Key Takeaways:
  1. Bittensor is transitioning from a purely experimental decentralized AI network to a performance-driven marketplace, demanding real-world utility and robust economic models from its subnets.
  2. Builders launching subnets must secure initial TAO liquidity and a clear, executable product roadmap from day one to navigate the competitive landscape and achieve emission.
  3. The network's continuous adaptation, from chain buys to MEV mitigation, signals a commitment to long-term stability and value.
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