The Physical World is AI's Final Boss: The speed of AI progress is now governed by the speed of transformers, permits, and power plants. The biggest opportunities are in solving these hard, physical-world bottlenecks.
Specialization is the Only Game in Town: General-purpose is dead. Lasting value will be created through specialized hardware, co-designed software, and tightly integrated systems that optimize for performance-per-watt.
Founders, Ditch the Thin Wrappers: The most durable businesses will not be built on other companies' models. Instead, they will create deep, proprietary feedback loops where the product and the model improve each other.
**AI is the Fed’s New Obsession.** The Fed's rate-cutting strategy is not just about inflation; it's a proactive measure against the "once in a generation" disruption AI poses to the white-collar labor market.
**Stablecoins are a Geopolitical Tool.** The global race to issue stablecoins is on, but the US is inadvertently winning. The more the world tokenizes, the more demand there is for US Treasuries, cementing the dollar's dominance.
**The Post-Retail Economy is Here.** The next major user demographic is not human—it's AI agents. These autonomous agents will conduct a massive volume of micropayments, creating an entirely new economic layer built on crypto rails.
Train Hard, Fight Easy. Autoppia’s "Infinite Web Arena" is a novel approach to AI training, forcing agents to become robust and adaptable by continuously exposing them to digital chaos.
Competition Breeds Excellence. The winner-take-all incentive model creates a hyper-competitive environment designed to accelerate innovation and rapidly advance the capabilities of AI agents on the network.
Revenue Equals Buybacks. Autoppia’s business model creates a direct link between commercial success and token value. Every dollar earned from selling AI worker services directly translates into buying pressure for the subnet token.
Personalization is the Killer App. The model’s breakthrough feature was zero-shot character consistency, creating an emotional connection that drove viral adoption. It proves utility is unlocked when technology feels personal.
Focus on the Floor, Not the Ceiling. The next wave of value will come from improving the worst-case outputs, not just the best. This "lemon picking" is essential for building trust and enabling reliable, real-world applications beyond creative tinkering.
Art is Intent; Models are Tools. AI’s role is to automate tedium, not replace creativity. The most compelling work will continue to come from skilled artists who use models to execute a specific vision, proving that the human with the idea remains irreplaceable.
AI Needs a Referee. Agents are programmed to win, not necessarily to follow the rules. Their tendency to "game the system" makes external, on-chain verification protocols essential for alignment and trust.
Trading is Just the Tip of the Spear. Crypto trading is the perfect initial use case due to its clear, objective metrics. The real goal is a decentralized "skill marketplace" where any organization can fund a competition to find the best agent for any task.
The Platform War is Here. A battle is unfolding between closed ecosystems like OpenAI, which aim for platform lock-in, and an open, decentralized future. This creates a massive opportunity for neutral evaluation layers to become the definitive source of truth for AI performance.
AI's Blind Spot is Unwritten Knowledge. The biggest barrier for AI in advanced problem-solving is accessing the "folklore" knowledge and intuition that experts build over a career but never write down.
The Future of Math is a Promotion, Not Obsolescence. AI will act as a powerful assistant that handles rote tasks, pushing mathematicians to focus exclusively on creative and abstract thinking.
The Next Revolution is AI-Powered Verification. Automated formal proof systems like Lean have the potential to eliminate errors from research papers, transforming peer review from a check on correctness to a judgment on a paper's novelty and impact.
AI's Blind Spot is "Folklore": The next great challenge for AI isn't raw calculation, but acquiring the unwritten, intuitive "folklore knowledge" that separates experts from students.
Mathematicians Become Creative Directors: As AI handles the technical grind, the human role in mathematics will shift from execution to creative direction—formulating novel problems and abstract models.
The End of Errors: Formal verification tools like Lean, powered by AI translators, are on the verge of revolutionizing math by creating a fully verifiable, error-free database of human knowledge, changing how proofs are published and reviewed.
AI's Blind Spot is "Folklore Knowledge." AI excels at digesting published literature but fails on problems requiring unwritten, community-held intuition, which remains a key human advantage for now. Jitomirskaya predicts her problem will take AI 10-20 years to solve.
Mathematicians Won't Be Replaced, They'll Be Upgraded. The future role of a mathematician is less about routine work and more about creative problem formulation. AI tools like Lean will handle verification, shifting peer review from "Is it correct?" to "Is it interesting?"
Math May Become a Sport. If AI eventually masters creativity, the human practice of mathematics may persist like chess—an activity pursued for its intrinsic value and intellectual challenge, even if a machine is the undisputed world champion.
Folklore Knowledge is AI’s Next Frontier. The true test for advanced AI in abstract fields is not solving problems from a textbook but acquiring the unwritten, intuitive knowledge that experts possess.
Automated Proof Verification Will Reshape Research. Within years, tools like Lean, powered by AI translators, will create a verifiable database of all mathematics, fundamentally changing how papers are published and refereed.
Human + Machine is the New Paradigm. AI will become an indispensable assistant, automating routine work and pushing mathematicians to focus on what humans still do best: true creativity and formulating entirely new models.
**Privacy Isn't a Feature; It's the Foundation.** For institutions, confidentiality is non-negotiable. Any network aiming to attract serious capital must offer privacy that allows for compliance without broadcasting every move to the world.
**Real Adoption Is a Long Game.** Chasing bull market hype is a losing strategy for enterprise adoption. Canton’s success with partners like Goldman Sachs, DTCC, and Citadel demonstrates the power of prioritizing utility and compliance over a premature token launch.
**The Next Wave Is Tokenizing Everything.** The goal is to move beyond crypto-native assets. The real prize is upgrading the rails for the world's existing financial system—equities, bonds, and treasuries—by making them digitally native, 24/7, and instantly settleable.
Despite the brutal sentiment, both speakers remain bullish, predicting a sharp reversal and a new all-time high for Bitcoin by the end of the year once macro clarity emerges.
Macro is King. Bitcoin's fate is now tied to the broader economy. Forget four-year cycles; the key catalyst is a resolution to the government shutdown, which could unlock pent-up energy in the market.
The Treasury Trade is Toast. The era of companies boosting their stock by simply buying Bitcoin is over. Expect a painful shakeout as the market demands real utility and revenue, leading to more forced selling.
The Internet Gets Its Native Wallet. x402 uses crypto to finally fulfill the internet's original vision of direct, peer-to-server payments, unlocking an economy of micropayments for everything from accessing an article to running an AI model.
The Ad-Supported Web Is Obsolete. AI agents that retrieve information without viewing ads are killing the web's 20-year-old business model. x402 provides the new economic rails for a pay-per-use internet where value is exchanged for resources, not attention.
Build Composable Money Legos. The biggest opportunity lies in creating simple, single-purpose APIs that agents can easily discover and compose. Think of it as building for the App Store of the emerging AI agent economy.
Distribution is the prize, not payments. The real money in gaming isn't in payment rails, which are being competed down to zero. The scarcest and most valuable asset is user attention, and Open Game Protocol is designed to monetize distribution.
Decouple to survive. Tying a single game to a single token creates a fatal dependency. A flexible, many-to-many protocol allows ecosystems to thrive by spreading risk and aligning incentives across multiple games and communities.
Content abundance requires new discovery. As AI makes game creation cheap and fast, the bottleneck shifts from production to discovery. Integrating games directly into high-intent surfaces like crypto wallets creates a powerful, non-advertising-based discovery channel.
Focus or Fade. As the industry matures, companies must shed non-core business units to become world-class at one thing. For Blockworks, that's data, not news.
Buy the Theme. Public market investors will pay a massive premium for the only stock representing a major crypto trend (e.g., Securitize for tokenization), often making it a better trade than trying to pick winners among underlying assets.
Growth is Subsidized. Major L1/L2 foundations are actively paying for enterprise adoption (e.g., Solana and Western Union). This is a standard business practice to kickstart network effects, but the long-term ROI remains unproven.
**Follow the Suits, Not the Shouts.** The market’s real signal is the massive disconnect between gloomy retail sentiment on social media and the unprecedented optimism from financial advisors and institutional platforms.
**Distribution is the New Kingmaker.** From Ripple buying prime brokerages to Tether leveraging its global south dominance, the primary battle is for distribution channels. The technical "best" solution is irrelevant if it can't reach users.
**Regulation Will Be a Slow Grind, Not a Big Bang.** Comprehensive crypto legislation is politically gridlocked. The industry’s integration into legacy finance will continue brick-by-brick through regulated products like ETFs, not sweeping bills from Congress.
