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AI Podcasts

October 30, 2025

"Is there an AI bubble?” Gavin Baker and David George

a16z

AI
Key Takeaways:
  1. **It's Not a Bubble, It's a Race.** The AI buildout is a rational, ROI-positive arms race funded by cash-rich giants. Unlike the dot-com era’s "dark fiber," today’s GPUs are fully utilized, generating immediate returns.
  2. **Sacrifice Margins or Die.** SaaS companies must abandon their obsession with 90% gross margins. In the AI era, lower margins signal that customers are actually using your product. Embrace them or become irrelevant.
  3. **The New Outcome Economy is Coming.** Business models will pivot from subscriptions to outcomes. AI will enable services to be priced on measurable results, from resolving a customer support ticket to booking the perfect vacation, squeezing inefficiency out of the market.
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October 29, 2025

Building the Real-World Infrastructure for AI, with Google, Cisco & a16z

a16z

AI
Key Takeaways:
  1. The Physical World is AI's Final Boss: The speed of AI progress is now governed by the speed of transformers, permits, and power plants. The biggest opportunities are in solving these hard, physical-world bottlenecks.
  2. Specialization is the Only Game in Town: General-purpose is dead. Lasting value will be created through specialized hardware, co-designed software, and tightly integrated systems that optimize for performance-per-watt.
  3. Founders, Ditch the Thin Wrappers: The most durable businesses will not be built on other companies' models. Instead, they will create deep, proprietary feedback loops where the product and the model improve each other.
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October 29, 2025

AI Agents, JPM Capitulates, Stablecoin Wars and the Fed Innovation: Bits + Bips

Unchained

AI
Key Takeaways:
  1. **AI is the Fed’s New Obsession.** The Fed's rate-cutting strategy is not just about inflation; it's a proactive measure against the "once in a generation" disruption AI poses to the white-collar labor market.
  2. **Stablecoins are a Geopolitical Tool.** The global race to issue stablecoins is on, but the US is inadvertently winning. The more the world tokenizes, the more demand there is for US Treasuries, cementing the dollar's dominance.
  3. **The Post-Retail Economy is Here.** The next major user demographic is not human—it's AI agents. These autonomous agents will conduct a massive volume of micropayments, creating an entirely new economic layer built on crypto rails.
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October 29, 2025

Bittensor Brief #13: Autoppia Subnet 36

Hash Rate pod - Bittensor $TAO & Subnets

AI
Key Takeaways:
  1. Train Hard, Fight Easy. Autoppia’s "Infinite Web Arena" is a novel approach to AI training, forcing agents to become robust and adaptable by continuously exposing them to digital chaos.
  2. Competition Breeds Excellence. The winner-take-all incentive model creates a hyper-competitive environment designed to accelerate innovation and rapidly advance the capabilities of AI agents on the network.
  3. Revenue Equals Buybacks. Autoppia’s business model creates a direct link between commercial success and token value. Every dollar earned from selling AI worker services directly translates into buying pressure for the subnet token.
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October 28, 2025

Google DeepMind Developers: How Nano Banana Was Made

a16z

AI
Key Takeaways:
  1. Personalization is the Killer App. The model’s breakthrough feature was zero-shot character consistency, creating an emotional connection that drove viral adoption. It proves utility is unlocked when technology feels personal.
  2. Focus on the Floor, Not the Ceiling. The next wave of value will come from improving the worst-case outputs, not just the best. This "lemon picking" is essential for building trust and enabling reliable, real-world applications beyond creative tinkering.
  3. Art is Intent; Models are Tools. AI’s role is to automate tedium, not replace creativity. The most compelling work will continue to come from skilled artists who use models to execute a specific vision, proving that the human with the idea remains irreplaceable.
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October 27, 2025

AI can learn logic. But can it learn folklore knowledge? - Svetlana Jitomirskaya

Epoch AI

AI
Key Takeaways:
  1. AI's Blind Spot is Unwritten Knowledge. The biggest barrier for AI in advanced problem-solving is accessing the "folklore" knowledge and intuition that experts build over a career but never write down.
  2. The Future of Math is a Promotion, Not Obsolescence. AI will act as a powerful assistant that handles rote tasks, pushing mathematicians to focus exclusively on creative and abstract thinking.
  3. The Next Revolution is AI-Powered Verification. Automated formal proof systems like Lean have the potential to eliminate errors from research papers, transforming peer review from a check on correctness to a judgment on a paper's novelty and impact.
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October 27, 2025

AI can learn logic. But can it learn folklore knowledge? - Svetlana Jitomirskaya

Epoch AI

AI
Key Takeaways:
  1. AI's Blind Spot is "Folklore": The next great challenge for AI isn't raw calculation, but acquiring the unwritten, intuitive "folklore knowledge" that separates experts from students.
  2. Mathematicians Become Creative Directors: As AI handles the technical grind, the human role in mathematics will shift from execution to creative direction—formulating novel problems and abstract models.
  3. The End of Errors: Formal verification tools like Lean, powered by AI translators, are on the verge of revolutionizing math by creating a fully verifiable, error-free database of human knowledge, changing how proofs are published and reviewed.
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October 28, 2025

The Best AI Agents are Competing for Rank (and Profit) | Andrew Hill, Recall CEO

The DCo Podcast

AI
Key Takeaways:
  1. AI Needs a Referee. Agents are programmed to win, not necessarily to follow the rules. Their tendency to "game the system" makes external, on-chain verification protocols essential for alignment and trust.
  2. Trading is Just the Tip of the Spear. Crypto trading is the perfect initial use case due to its clear, objective metrics. The real goal is a decentralized "skill marketplace" where any organization can fund a competition to find the best agent for any task.
  3. The Platform War is Here. A battle is unfolding between closed ecosystems like OpenAI, which aim for platform lock-in, and an open, decentralized future. This creates a massive opportunity for neutral evaluation layers to become the definitive source of truth for AI performance.
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October 27, 2025

AI can learn logic. But can it learn folklore knowledge? - Svetlana Jitomirskaya

Epoch AI

AI
Key Takeaways:
  1. AI's Blind Spot is "Folklore Knowledge." AI excels at digesting published literature but fails on problems requiring unwritten, community-held intuition, which remains a key human advantage for now. Jitomirskaya predicts her problem will take AI 10-20 years to solve.
  2. Mathematicians Won't Be Replaced, They'll Be Upgraded. The future role of a mathematician is less about routine work and more about creative problem formulation. AI tools like Lean will handle verification, shifting peer review from "Is it correct?" to "Is it interesting?"
  3. Math May Become a Sport. If AI eventually masters creativity, the human practice of mathematics may persist like chess—an activity pursued for its intrinsic value and intellectual challenge, even if a machine is the undisputed world champion.
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Crypto Podcasts

January 13, 2026

How Claude Code is Changing the World with Nick Emmons

The Rollup

Crypto
Key Takeaways:
  1. The transition from human-centric interfaces to agent-first protocols. As agents become the primary users, the internet will be rebuilt around machine-readable data and crypto-native payment rails.
  2. Integrate Model Context Protocol (MCP) servers into your workflow immediately. Use parallel Claude instances to act as both programmer and reviewer to bypass context window degradation.
  3. Software is no longer a product: it is a utility. Over the next year, the winners will be those who control the data graphs and the distribution channels, not the ones writing the code.
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January 12, 2026

Claude Opus 4.5’s Breakout Moment & Investing in 2026 with Qiao Wang

Empire

Crypto
Key Takeaways:
  1. The Macro Pivot: Proprietary data and enterprise switching costs are the only walls left standing as AI commoditizes the act of writing code.
  2. The Tactical Edge: Build internal tools using natural language agents to automate specific, low-volume workflows that third-party vendors ignore.
  3. The Bottom Line: The billion-dollar company with a single employee is no longer a fantasy; it is a mathematical certainty for those who master the prompt over the next twelve months.
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January 13, 2026

How Claude Code is Changing the World with Nick Emmons

The Rollup

Crypto
Key Takeaways:
  1. The migration from human-centric interfaces to agent-first protocols where software is a temporary utility rather than a permanent product.
  2. Use Git and MCP servers to give your agents a persistent memory and toolset, allowing them to work autonomously through complex loops.
  3. Software is no longer the prize; it is the commodity. Your value in the next year depends on how well you direct the agents that build it.
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January 12, 2026

HIP-3 Market Design and Felix’s Role | Charlie, Felix Protocol

0xResearch

Crypto
Key Takeaways:
  1. The Macro Strategic Pivot: Vertical Consolidation. Protocols are moving away from modularity toward integrated stacks to capture maximum fee revenue.
  2. The Tactical Edge: Monitor BLP Rates. Watch the spread between Felix and Hyperliquid’s native lending rates. Capital will migrate to the platform offering the lowest borrow cost for margin trading.
  3. The Bottom Line: Hyperliquid is winning by becoming a DeFi Super App rather than just a perp engine. Its success over the next year depends on its ability to manage UI fragmentation while keeping all revenue inside the Hype ecosystem.
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January 12, 2026

Is Canton a Real Blockchain? | Canton Founder Yuval Rooz

Bankless

Crypto
Key Takeaways:
  1. The Macro Transition: We are seeing a split between "Pure Crypto" for sovereignty and "Institutional Rails" for global capital markets.
  2. The Tactical Edge: Monitor Broadridge volume to gauge the actual velocity of institutional on-chain adoption.
  3. The Bottom Line: The next decade is not about crypto replacing banks. It is about banks adopting crypto's efficiency while keeping their legal moats.
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January 12, 2026

Who Actually Owns the Aave Brand -- the DAO or Labs? Uneasy Money

Unchained

Crypto
Key Takeaways:
  1. The "Fat App" thesis is evolving into the "Sovereign Brand" thesis where the front-end is the ultimate moat.
  2. Audit your protocol's meatspace dependencies—domains, trademarks, and front-ends—before they become points of failure.
  3. Decentralization isn't just about smart contracts; it is about ensuring the front door to your protocol cannot be locked by a single executive.
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