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AI Podcasts

November 17, 2025

Hash Rate - Ep 145 - TAO Subnets Templar (3), Basilica (39), Grail (81)

Hash Rate pod - Bittensor $TAO & Subnets

AI
Key Takeaways:
  1. **A New Market is Born:** Templar isn't just cheaper; it enables something that was previously impossible for 99% of the world. Democratizing pre-training means anyone can build a truly custom, sovereign AI.
  2. **Productization is Underway:** Covenant is no longer just a research project. With enterprise sales in motion, the focus is now on revenue. The team has committed that 100% of fees from custom training will be used to buy back its tokens.
  3. **Economics are Being Rewritten:** Basilica’s incentive mechanism is a direct critique of unsustainable models on other compute subnets. Its focus on profitability and positive TAO flow sets a new standard for economic design on Bittensor.
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November 17, 2025

Bryan Johnson: Don’t Die, Beating Entropy, AI Alignment & The Two-Species Future

Bankless

AI
Key Takeaways:
  1. AI Forces a Moral Reboot. The emergence of superintelligence renders our current societal goals dangerously obsolete. Survival must become the new prime directive.
  2. Existence is a Team Sport. The "Don't Die" philosophy is a collective mission ("we don't die") to ensure species-wide survival, not a selfish quest for individual immortality.
  3. Prepare for the Biological Sandbox. Humanity is moving from manipulating physical atoms and digital bits to programming our own biology—a frontier with both unimaginable potential and catastrophic risk.
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November 17, 2025

Emmett Shear on Building AI That Actually Cares: Beyond Control and Steering

a16z

AI
Key Takeaways:
  1. Stop Trying to “Steer” AGI. The control paradigm is a dead end. The goal isn’t a more obedient tool; it’s a trustworthy teammate. We must shift from engineering control to cultivating care.
  2. Alignment is a Process, Not a Product. True alignment isn't a fixed set of rules. It’s a dynamic process of moral learning, akin to raising a child. AIs that only follow rules are brittle and dangerous.
  3. Build for Cooperation, Not Command. The technical path forward involves training AIs in rich, multi-agent environments where they must learn cooperation and theory of mind—the foundational skills for becoming a good member of a group.
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November 16, 2025

Rawson Haverty presents "US & China AI: Lessons from Across the Pacific" | dAGI Summit 2025

Delphi Digital

AI
Key Takeaways:
  1. US Leads in Capital-Intensive Frontier AI; China Excels at Industrial Diffusion. The US leverages deep capital markets for its massive compute buildout and AGI research, while China uses state direction to embed AI into its vast industrial base via open-source models and hardware.
  2. Market Structure Dictates AI Strategy. The US "efficient oligopoly" model prioritizes global dominance and profit reinvestment by a few players. China's "subjugated swarm" model creates intense domestic competition, driving down prices and accelerating adoption at the cost of profitability.
  3. Geopolitical Tension May Be a Necessary Stabilizer. The competition between the US's freedom-oriented, frontier-pushing approach and China's stability-focused, diffusion-driven model creates a complementary tension that could be essential for navigating the "narrow corridor" between AI-driven totalitarianism and uncontrollable chaos.
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November 13, 2025

How Will AI Change Gaming Development? (A Dev’s Take)

The DCo Podcast

AI
Key Takeaways:
  1. Development timelines are collapsing from months to days. AI allows developers to swap entire asset libraries or generate new game concepts at unprecedented speed, turning a two-month art project into a day's work.
  2. The lifespan of any single game is shrinking. Prepare for a world of disposable entertainment. As AI floods the market with content, the strategy will pivot from creating one long-lasting hit to deploying a rapid succession of engaging experiences.
  3. Games are the next evolution of the attention economy. Just as memes became a core tool for community-building around tokens, easily created games will be the next engine for capturing and directing user attention in a hyper-competitive digital world.
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November 11, 2025

AI Nerves, Crypto Realism, Privacy Coins, & Lessons From Trading

1000x Podcast

AI
Key Takeaways:
  1. Adopt a Stock Picker's Mentality. The crypto market is no longer a monolith where a rising tide lifts all boats. Focus on assets with real products, user growth, and cash flow, as the gap between winners and losers will only widen.
  2. Shorting is a Tactical Assault, Not a Siege. Don't "invest" in a short. The only viable short strategies are tactical, targeting specific events like VC unlocks or news-driven spikes. Otherwise, even "total scams" can 5x against you.
  3. Cultivate a Goldfish's Memory. The most critical trading skill is learning how to change your mind. Cut losing trades, forget the loss (but remember the lesson), and redeploy capital without emotional baggage. Stubbornness is a portfolio killer.
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November 11, 2025

Grant Lee: Building Gamma’s AI Presentation Company to 100 Million Users

a16z

AI
Key Takeaways:
  1. Word-of-mouth isn't a feature; it's the engine. Before spending a dime on marketing, obsess over the first 30 seconds of the user experience until people can't help but share it.
  2. Being different is better than being better. Don't build incrementally better slideware. Redefine the core primitives of your category, as Gamma did by moving beyond the 16x9 slide.
  3. Hire painfully slowly to protect your DNA. Resisting the temptation to scale headcount with user growth is a superpower. The goal isn't to hit a hiring target; it's to hire the best people.
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November 7, 2025

Amjad Masad & Adam D’Angelo: How Far Are We From AGI?

a16z

AI
Key Takeaways:
  1. AGI Is a Definitional Debate. Progress toward an AI that can replace a remote worker is happening fast. However, achieving "true" human-like learning efficiency may require an entirely new paradigm beyond scaling current LLMs.
  2. The New Creator Economy Is Code. AI is turning software development into a mainstream creative pursuit, empowering a new class of solo entrepreneurs who can build what previously required entire teams.
  3. Incumbents Learned Their Lesson. Unlike past tech shifts, today's giants are aggressively adopting AI, making it both a sustaining *and* disruptive force. The market is large enough for both incumbents and startups to create massive value.
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November 6, 2025

Mark Zuckerberg & Priscilla Chan: How AI Will Cure All Disease

a16z

AI
Key Takeaways:
  1. Build the Tools, Not Just the House: CZI’s greatest leverage comes from creating open-source tools and datasets. By building the fundamental infrastructure, they empower the entire scientific community—from academic labs to startups—to accelerate discovery.
  2. Data Is the New Microscope: The future of biology hinges on a tight feedback loop between generating novel, purpose-built datasets and training domain-specific AI models on them. This synergy is unlocking insights that were previously impossible.
  3. Virtual Biology Is the Next Frontier: Simulating biology computationally with "virtual cells" will become the new standard for research, enabling scientists to test riskier hypotheses faster and cheaper, dramatically compressing the timeline for major breakthroughs.
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Crypto Podcasts

February 28, 2025

How Blackbird Is Unlocking Crypto's App Ecosystem | Ben Leventhal & Jesse Walden

Lightspeed

Crypto

Key Takeaways:

  • :
  • 1. Blackbird is pioneering a blockchain-based loyalty and payment system that could redefine restaurant economics by eliminating costly intermediaries.
  • 2. The dual-token system of Fly and F2 ensures both consumer engagement and network governance, offering a unique value proposition.
  • 3. For developers and investors, Blackbird exemplifies how blockchain can be leveraged to create real-world value and user ownership, setting a precedent for future applications.
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February 28, 2025

How To Win in Crypto Investing with Akshat Vaidya

The Rollup

Crypto

Key Takeaways:

  • :
  • 1. Understanding the cyclical nature of crypto markets is essential for strategic investment. Deploying capital during downturns can lead to significant gains.
  • 2. Integrity, humility, and adaptability are critical traits for founders seeking long-term success in the crypto space.
  • 3. Investors should focus on deep research to identify undervalued opportunities, particularly in DeFi and real-world assets.
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February 27, 2025

Kaito’s Airdrop: Genius or Giveaway Gone Wrong? | Analyst Round Table

0xResearch

Crypto

Key Takeaways:

  • :
  • 1. Bybit’s Large-Scale Hack Highlights the Need for Robust Security: The $1.4 billion ETH breach underscores the importance of advanced security measures and resilient infrastructure in preventing and mitigating massive crypto exploits.
  • 2. Sustainable Airdrop Models are Crucial for Long-Term Success: Kaido’s extensive airdrop strategy reveals the tension between immediate community engagement and the necessity for sustainable token distribution practices to ensure lasting protocol viability.
  • 3. Regulatory Clarity Will Shape the Future of Token Launches: As regulatory bodies like the SEC begin to provide clearer guidelines, the crypto industry must adapt to new rules that can legitimize token offerings and foster a more stable market environment.
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February 27, 2025

Why MegaETH Leaves Consensus to Ethereum

The DCo Podcast

Crypto

Key Takeaways:

  • :
  • 1. Enhanced Security through Ethereum: By outsourcing consensus to Ethereum, MegaETH leverages a highly secure and decentralized network, minimizing vulnerabilities associated with centralized consensus mechanisms.
  • 2. Performance Optimization: Avoiding its own consensus process allows MegaETH to reduce latency and boost transaction speeds, making it a high-performance blockchain solution.
  • 3. Strategic Leveraging of Established Protocols: Developers and investors should consider the benefits of utilizing established consensus protocols like Ethereum’s to ensure robust security while focusing on other aspects of blockchain performance.
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February 25, 2025

The State Of Crypto & AI | Illia Polosukhin & Bowen Wang

Lightspeed

Crypto
AI
Infrastructure

Key Takeaways:

  • :
  • 1. NEAR is pioneering a unified blockchain infrastructure integrating AI, eliminating the need for multiple chains and enhancing user experience.
  • 2. The launch of NEAR 2.0 with fully sharded architecture and reduced block times positions NEAR as a scalable and high-performance blockchain platform.
  • 3. NEAR’s focus on chain abstraction and Trusted Execution Environments sets it apart from other blockchain and Layer 2 solutions, offering a more seamless and secure user experience.
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February 25, 2025

Futarchy Deep Dive: Can Markets Make Better Decisions? | Proph3t

Bell Curve

Crypto
AI
Others

Key Takeaways:

  • :
  • 1. Futarchy harnesses market efficiency to potentially outperform traditional governance in decision-making.
  • 2. Crypto’s regulatory resistance is essential for implementing innovative governance models like futarchy.
  • 3. Enhanced liquidity and decentralized capital formation are critical for the scalability and success of futarchy-based organizations.
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