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AI Podcasts

December 20, 2025

Are AI Benchmarks Telling The Full Story? [SPONSORED]

Machine Learning Street Talk

AI
Key Takeaways:
  1. Strategic Shift: The market will increasingly demand AI models evaluated on human-centric metrics, not just technical benchmarks. Companies prioritizing user experience and safety will gain a competitive edge.
  2. Builder/Investor Note: Investigate companies developing or utilizing advanced, demographically representative human evaluation frameworks. These are crucial for building defensible, user-aligned AI products.
  3. The "So What?": Over the next 6-12 months, expect a growing focus on AI safety, ethical alignment, and nuanced human preference data. The "Wild West" of AI evaluation is ending, paving the way for more robust, trustworthy systems.
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December 17, 2025

Rethinking Pre-Training for Agentic AI [Aakanksha Chowdhery] - 759

The TWIML AI Podcast with Sam Charrington

AI
Key Takeaways:
  1. Strategic Implication: The next frontier in AI is agentic, and progress hinges on fundamental pre-training innovation, not just post-training optimizations.
  2. Builder/Investor Note: Focus on teams with deep experience in scaling and debugging large models, as this is a high-capital, high-risk endeavor. Builders should prioritize developing new benchmarks for agentic capabilities.
  3. The "So What?": The industry needs to move beyond next-token prediction and static benchmarks to unlock truly capable, self-correcting AI agents in the next 6-12 months.
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December 17, 2025

Code World Model: Building World Models for Computation – Jacob Kahn, FAIR Meta

AI Engineer

AI
Key Takeaways:
  1. Shift in AI Development: The focus moves from syntax-aware code generation to execution-aware reasoning, enabling more robust and intelligent code agents.
  2. Builder/Investor Note: Prioritize tools and platforms that support explicit execution modeling and highly asynchronous, high-throughput RL training for agentic systems.
  3. The "So What?": AI that can simulate complex systems internally will drastically reduce development and testing costs, accelerating innovation in software and distributed systems over the next 6-12 months.
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December 17, 2025

AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs

AI Engineer

AI
Key Takeaways:
  1. Strategic Shift: AI-driven kernel generation is not replacing human genius but augmenting it, allowing experts to focus on novel breakthroughs while AI automates the application of known optimizations across a complex hardware landscape.
  2. Builder/Investor Note: Focus on robust validation and hardware-in-the-loop systems. Claims of "AI inventing new algorithms" in this domain are premature. The real value is in automating the "bag of tricks" for heterogeneous compute.
  3. The "So What?": This technology is critical for scaling agentic AI workloads. Expect significant investment in tools that abstract hardware complexity and enable efficient, automated optimization, driving down the cost of AI inference in the next 6-12 months.
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December 18, 2025

AI Consulting in Practice – NLW, Super ai

AI Engineer

AI
Key Takeaways:
  1. The Agent Economy is Here: Enterprises are moving past pilots with AI agents. Builders should focus on orchestration layers and human-agent interaction design.
  2. ROI Measurement is the Next Frontier: Investors should look for solutions that help organizations accurately track and attribute AI value beyond traditional metrics.
  3. Strategic AI, Not Spot Solutions: The biggest wins come from systematic, cross-organizational AI strategies that target new capabilities and revenue growth, not just incremental time savings.
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December 18, 2025

How to build an AI native company (even if your company is 50 years old) – Dan Shipper, Every

AI Engineer

AI
Key Takeaways:
  1. The 100% AI adoption threshold is a step-function change, not incremental. Companies that commit fully will outpace those with partial integration.
  2. Builders should prioritize "compounding engineering" by codifying knowledge into reusable prompts. This builds an organizational memory that accelerates future development exponentially.
  3. Re-evaluate team structures and roles. Single engineers can own complex products, and even technical managers can contribute code, shifting how organizations operate.
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December 17, 2025

“How We Can Eliminate Crime” | Ben Horowitz and Garrett Langley

a16z

AI
Key Takeaways:
  1. Effective crime reduction requires a shift from reactive punishment to proactive, intelligence-driven deterrence, making it highly probable for criminals to be caught.
  2. The market for AI-powered public safety technology, particularly solutions that integrate data for precision and accountability, presents a significant opportunity. Public-private partnerships are a key funding mechanism.
  3. Over the next 6-12 months, expect to see more cities adopt advanced surveillance and AI tools, driven by private funding, as they seek to improve safety and address staffing shortages without resorting to ineffective, broad-stroke policies.
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December 18, 2025

Two Futures | Runtime 2025

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next decade will be defined by who builds the core infrastructure for intelligence. This is where the most significant value and influence will accrue.
  2. Builder/Investor Note: Direct capital and talent towards foundational AI components—chips, models, and interoperable systems. Avoid the temptation to only build at the application layer.
  3. The So What?: The window for shaping the future of intelligence is now. Engage in the deepest, most complex challenges to secure a footprint in this new era.
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December 18, 2025

The EU and the not-so-simple macroeconomics of AI – Luis Garicano

Epoch AI

AI
Key Takeaways:
  1. Strategic Implication: The global AI race is a zero-sum game for foundational models. Europe's best strategy is a "smart second mover" approach, focusing on the implementation layer by ensuring interoperability and data portability.
  2. Builder/Investor Note: Invest in AI that achieves true autonomy and enhances expert productivity. Be wary of markets stifled by over-regulation, which can impede AI adoption and growth.
  3. The "So What?": Europe faces a critical juncture. Without embracing AI-driven growth, its demographic and debt problems will worsen, leading to higher interest rates without the corresponding economic expansion.
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Crypto Podcasts

February 24, 2025

How Sapien Lets Anyone Earn by Creating Datasets

Outpost | Crypto AI

AI
Crypto
Infrastructure

Key Takeaways:

  • 1. Decentralized data labeling can significantly reduce costs while enhancing data quality through global expert networks.
  • 2. The synergy between crypto and AI unlocks new possibilities for scalable and efficient AI model training.
  • 3. Proprietary, purpose-built datasets are becoming essential for enterprises to maintain a competitive edge in AI development.
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February 23, 2025

Crypto Circus Never Ends: Hacks, Grifts, and Kanye’s Coin?

Unchained

Crypto
DeFi

Key Takeaways:

  • :
  • 1. Major Hacks Undermine Trust: The Bybit hack exemplifies the vulnerabilities in crypto security and the sophisticated methods of state-affiliated hackers.
  • 2. Insider Scandals Expose Systemic Flaws: The Libra scandal reveals deep-seated issues in meme coin launches, highlighting the need for greater transparency and regulation.
  • 3. Regulatory Shifts Offer Hope: Positive moves by the SEC and the CFTC signal a more supportive regulatory landscape, encouraging legitimate crypto innovation.
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February 21, 2025

Is Hashflow The Next Hyperliquid?

The Rollup

DeFi
Crypto
Infrastructure

Key Takeaways:

  • 1. ZK Technology is Transformative: Zero-Knowledge proofs are not only scalable and secure but are also finding essential applications in decentralized finance, particularly in proving exchange solvency without sacrificing performance.
  • 2. Hashflow Leads with Innovation: By leveraging ZK, Hashflow is positioned as a frontrunner in creating high-performance, secure exchanges that offer a user-friendly experience, potentially setting a new standard for the industry.
  • 3. Real-Time Proving is the Future: The advancement towards real-time proving will revolutionize cross-chain interactions and user experiences, making decentralized exchanges as fast and reliable as their centralized counterparts.
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February 21, 2025

$LIBRA Memecoin Scandal Rocks Argentina & The U.S. Fed’s Next Move! Pivot?

Bankless

Crypto
Others

Key Takeaways

  • Heightened Fraud Risks: The $LIBRA scandal underscores the perpetual risk of manipulation in memecoin markets, urging investors to exercise extreme caution.
  • Evolving Airdrop Strategies: Airdrops are becoming more sophisticated, but misalignment between expectations and reality continues to challenge their effectiveness.
  • Regulatory Balance Needed: While the SEC’s efforts to curb fraud are crucial, the crypto industry must develop robust self-regulation to complement external oversight

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February 21, 2025

Monetary Properties of SOL and ETH

The Rollup

Crypto
DeFi

Key Takeaways

  • Ethereum Outshines Solana: Ethereum’s superior decentralization and monetary properties make it a more reliable asset compared to Solana.
  • Decentralization is Crucial: The degree of decentralization directly impacts an asset’s stability and future predictability, influencing investor confidence.
  • Bitcoin’s Influence Remains Strong: Despite Ethereum’s strengths, Bitcoin’s dominance sets the benchmark for decentralized digital assets, shaping the competitive landscape for other cryptocurrencies.

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February 21, 2025

A New Era For Crypto In The U.S | Rebecca Rettig

Lightspeed

Crypto
DeFi

Key Takeaways:

  • 1. Regulatory Clarity is Crucial: Effective engagement with the SEC can pave the way for more robust and compliant crypto innovations.
  • 2. Decentralization Enhances Stability: Solana’s efforts to decentralize through Jeto Labs contribute to a more resilient and trustworthy network.
  • 3. DeFi as a Game-Changer: The growth of DeFi offers unprecedented opportunities for financial autonomy and market efficiency, driving future crypto adoption.
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