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AI Podcasts

December 13, 2025

Minimax M2 – Olive Song, MiniMax

AI Engineer

AI
Key Takeaways:
  1. **The "Small is Mighty" Paradigm:** Don't underestimate smaller, specialized models. M2 proves that smart engineering, real-world feedback, and iterative reasoning can outperform larger models in specific, high-value domains.
  2. **Builders, Embrace Iteration:** Design your agents with "interleaved thinking." The ability to self-correct and adapt to noisy environments is critical for real-world utility.
  3. **The "So What?":** The next wave of AI agents will be defined by their robustness, cost-effectiveness, and ability to generalize across dynamic environments. M2 is a blueprint for building practical, scalable AI that developers will actually integrate into their daily workflows.
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December 11, 2025

No Priors Ep. 143 | With ElevenLabs Co-Founder Mati Staniszewski

No Priors: AI, Machine Learning, Tech, & Startups

AI
Key Takeaways:
  1. Strategic Shift: The future of human-computer interaction is voice-first, moving from static content to dynamic, personalized, and agentic experiences.
  2. Builder/Investor Note: Defensibility in AI is increasingly found in deep product layers, specialized architectural breakthroughs (especially in audio), and robust ecosystems, not just raw model scale.
  3. The "So What?": Over the next 6-12 months, expect to see significant advancements in proactive AI agents, immersive media, and personalized education, with voice as the core interface.
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December 10, 2025

The Unicorn Founder Who Delegated Everything.

a16z

AI
Key Takeaways:
  1. The AI-Delegation Revolution is Here: Start experimenting with AI tools like ChatGPT for delegation now. The future involves proactive machine assistants deeply integrated into your workflow.
  2. Builders & Investors: Focus on "How to Delegate": The biggest constraint isn't finding assistants, but teaching clients how to delegate effectively. Tools and services that educate delegators will win.
  3. Reclaim Your Ambition: By offloading the mundane, you free up mental bandwidth to think bigger, pursue more ambitious goals, and ultimately, control your most valuable asset: time.
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December 12, 2025

AI Eats the World: Benedict Evans on the Next Platform Shift

a16z

AI
Key Takeaways:
  1. Strategic Implication: The AI bubble is inevitable. Focus on defensible positions: deep product integration, proprietary data, and distribution, rather than just raw model performance.
  2. Builder/Investor Note: The opportunity lies in productizing AI for specific "jobs to be done" within niche industries, creating intuitive UIs, and building in validation, not just building another foundational model.
  3. The "So What?": We're about to figure out the true "job to be done" for many industries. AI will unbundle existing businesses by exposing their hidden inefficiencies or non-obvious defensibilities.
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December 13, 2025

The Mathematical Foundations of Intelligence [Professor Yi Ma]

Machine Learning Street Talk

AI
Key Takeaways:
  1. Embrace Parsimony and Self-Consistency: Adopt these principles as guiding forces in AI design. Build models that not only compress data efficiently but also maintain a high degree of self-consistency to ensure accurate and reliable world models.
  2. Focus on Abstraction, Not Just Memorization: Prioritize developing systems that can abstract knowledge beyond mere memorization. Move beyond surface-level compression and aim for models that can discover and reason about the underlying principles of the world.
  3. Understand and Reproduce the Brain’s Mechanisms: Focus on understanding and reproducing the mechanisms in the human brain that enable deductive reasoning, logical thinking, and the creation of new scientific theories to truly push AI to the next level.
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December 10, 2025

Nav Kumar: Trishool, AI Alignment, Subnet 23, Mechanistic Interpretability, Rogue LLMs | Ep. 75

Ventura Labs

AI
Key Takeaways:
  1. **Prioritize AI Safety Research:** Invest aggressively in understanding and mitigating AI risks to safeguard humanity against potential rogue LLMs.
  2. **Support Decentralized AI Alignment:** Champion decentralized platforms like Bit Tensor and initiatives like Trishool that promote open and transparent AI alignment research.
  3. **Embrace Mechanistic Interpretability:** Drive the development of tools that enable us to understand and control the internal workings of AI models, ensuring alignment with human values.
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December 10, 2025

Everyone Needs an Assistant. Here’s Why.

a16z

AI
Key Takeaways:
  1. Embrace Delegation as a Foundational Skill: Whether you leverage AI or human support, mastering delegation is paramount for unlocking personal and professional potential.
  2. Prioritize Time Ownership: Recognize time as your most valuable asset and design your life and calendar around your highest goals.
  3. Start Small, Scale Intentionally: Begin with affordable AI tools and gradually incorporate human assistance as your budget and needs evolve, building trust and compounding leverage over time.
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December 8, 2025

Building The Chip That Could Unlock AGI | Naveen Rao

a16z

AI
Key Takeaways:
  1. **Embrace Analog:** Explore and invest in analog computing solutions to overcome the energy limitations of current digital AI systems.
  2. **Prioritize Causality:** Shift focus towards AI models that incorporate time and causality, potentially unlocking more advanced and human-like intelligence.
  3. **Support Hardware Innovation:** Invest in and foster startups like Unconventional AI that are tackling fundamental challenges in AI hardware.
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December 8, 2025

Why AI Will Have To Run On Blockchains

The DCo Podcast

AI
Key Takeaways:
  1. Blockchain is essential for AI to ensure censorship resistance and uninterrupted accessibility.
  2. Trustworthy AI agents require on-chain governance to manage assets securely and transparently.
  3. AI agents can drastically accelerate blockchain adoption and optimize corporate processes.
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Crypto Podcasts

January 21, 2026

Markets Are Entering A Wartime Economy | Cem Karsan

Forward Guidance

Crypto
Key Takeaways:
  1. The transition from a supply-side model to a populist-driven wartime economy makes inflation a permanent feature rather than a bug.
  2. Rotate out of traditional portfolios into non-correlated volatility strategies and hard assets.
  3. The next decade belongs to those who recognize that the rules-based order has been replaced by a raw competition for strategic resources.
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January 21, 2026

How Nansen’s New Trading Agent Makes It Easier to Follow the Smart Money Onchain

Unchained

Crypto
Key Takeaways:
  1. The commoditization of technical infrastructure means alpha moves from who has the data to who has the best prompts.
  2. Test agentic workflows with small capital amounts to identify where natural language outperforms manual execution.
  3. The next 12 months will see a transition from manual click-and-sign trading to intent-based portfolio management.
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January 21, 2026

Quadrillions: How to Win the World | Chris Maurice

Empire

Crypto
Key Takeaways:
  1. The transition from public peer-to-peer narratives to private B2B infrastructure that connects local bonds to global stablecoins.
  2. Build for the back end of the product by integrating with local financial institutions that already own the user relationship.
  3. The next year will see the rise of global dollar-denominated accounts, making the US dollar a truly borderless commodity.
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January 21, 2026

Market Structure, Macro Volatility, and the Next Phase of Crypto | Michael Anderson & Vance Spencer

Bell Curve

Crypto
Key Takeaways:
  1. The transition from L1 wars to on-chain businesses means capital is moving toward protocols with clear revenue-sharing models.
  2. Monitor Bitmine’s ETH accumulation and the launch of Blackwell GPU clusters. Position in protocols that bridge the gap between AI infrastructure financing and stablecoin liquidity.
  3. The next year belongs to the capital assassins who can blend meme-driven distribution with hard-nosed corporate finance.
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January 20, 2026

LIVE: MegaETH, Pump, NYSE | 0xResearch

0xResearch

Crypto
Key Takeaways:
  1. The Macro Migration: Value is moving from base layers to applications that own the end-user relationship. This transition favors integrated platforms over modular protocols.
  2. The Tactical Edge: Monitor platforms that successfully integrate vertical services like Phantom or Pump.fun. These Everything Apps are the most likely candidates for sustainable revenue growth.
  3. The Bottom Line: The next six months will favor teams that prioritize revenue and user stickiness over speculative token launches.
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January 19, 2026

Why Grayscale Sees ATHs Before Q3, With ETH Outperforming: Bits + Bips

Unchained

Crypto
Key Takeaways:
  1. The erosion of central bank independence turns fiscal debt into a marketing campaign for hard-capped digital assets.
  2. Accumulate Ethereum and top-tier smart contract platforms that offer staking yields before the $40 trillion advised wealth pool begins its structural rotation.
  3. The next year will be defined by the transition from speculative retail trading to structural institutional accumulation driven by a global flight from debasing fiat.
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