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AI Podcasts

December 13, 2025

Minimax M2 – Olive Song, MiniMax

AI Engineer

AI
Key Takeaways:
  1. **The "Small is Mighty" Paradigm:** Don't underestimate smaller, specialized models. M2 proves that smart engineering, real-world feedback, and iterative reasoning can outperform larger models in specific, high-value domains.
  2. **Builders, Embrace Iteration:** Design your agents with "interleaved thinking." The ability to self-correct and adapt to noisy environments is critical for real-world utility.
  3. **The "So What?":** The next wave of AI agents will be defined by their robustness, cost-effectiveness, and ability to generalize across dynamic environments. M2 is a blueprint for building practical, scalable AI that developers will actually integrate into their daily workflows.
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December 11, 2025

No Priors Ep. 143 | With ElevenLabs Co-Founder Mati Staniszewski

No Priors: AI, Machine Learning, Tech, & Startups

AI
Key Takeaways:
  1. Strategic Shift: The future of human-computer interaction is voice-first, moving from static content to dynamic, personalized, and agentic experiences.
  2. Builder/Investor Note: Defensibility in AI is increasingly found in deep product layers, specialized architectural breakthroughs (especially in audio), and robust ecosystems, not just raw model scale.
  3. The "So What?": Over the next 6-12 months, expect to see significant advancements in proactive AI agents, immersive media, and personalized education, with voice as the core interface.
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December 10, 2025

The Unicorn Founder Who Delegated Everything.

a16z

AI
Key Takeaways:
  1. The AI-Delegation Revolution is Here: Start experimenting with AI tools like ChatGPT for delegation now. The future involves proactive machine assistants deeply integrated into your workflow.
  2. Builders & Investors: Focus on "How to Delegate": The biggest constraint isn't finding assistants, but teaching clients how to delegate effectively. Tools and services that educate delegators will win.
  3. Reclaim Your Ambition: By offloading the mundane, you free up mental bandwidth to think bigger, pursue more ambitious goals, and ultimately, control your most valuable asset: time.
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December 12, 2025

AI Eats the World: Benedict Evans on the Next Platform Shift

a16z

AI
Key Takeaways:
  1. Strategic Implication: The AI bubble is inevitable. Focus on defensible positions: deep product integration, proprietary data, and distribution, rather than just raw model performance.
  2. Builder/Investor Note: The opportunity lies in productizing AI for specific "jobs to be done" within niche industries, creating intuitive UIs, and building in validation, not just building another foundational model.
  3. The "So What?": We're about to figure out the true "job to be done" for many industries. AI will unbundle existing businesses by exposing their hidden inefficiencies or non-obvious defensibilities.
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December 13, 2025

The Mathematical Foundations of Intelligence [Professor Yi Ma]

Machine Learning Street Talk

AI
Key Takeaways:
  1. Embrace Parsimony and Self-Consistency: Adopt these principles as guiding forces in AI design. Build models that not only compress data efficiently but also maintain a high degree of self-consistency to ensure accurate and reliable world models.
  2. Focus on Abstraction, Not Just Memorization: Prioritize developing systems that can abstract knowledge beyond mere memorization. Move beyond surface-level compression and aim for models that can discover and reason about the underlying principles of the world.
  3. Understand and Reproduce the Brain’s Mechanisms: Focus on understanding and reproducing the mechanisms in the human brain that enable deductive reasoning, logical thinking, and the creation of new scientific theories to truly push AI to the next level.
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December 10, 2025

Nav Kumar: Trishool, AI Alignment, Subnet 23, Mechanistic Interpretability, Rogue LLMs | Ep. 75

Ventura Labs

AI
Key Takeaways:
  1. **Prioritize AI Safety Research:** Invest aggressively in understanding and mitigating AI risks to safeguard humanity against potential rogue LLMs.
  2. **Support Decentralized AI Alignment:** Champion decentralized platforms like Bit Tensor and initiatives like Trishool that promote open and transparent AI alignment research.
  3. **Embrace Mechanistic Interpretability:** Drive the development of tools that enable us to understand and control the internal workings of AI models, ensuring alignment with human values.
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December 10, 2025

Everyone Needs an Assistant. Here’s Why.

a16z

AI
Key Takeaways:
  1. Embrace Delegation as a Foundational Skill: Whether you leverage AI or human support, mastering delegation is paramount for unlocking personal and professional potential.
  2. Prioritize Time Ownership: Recognize time as your most valuable asset and design your life and calendar around your highest goals.
  3. Start Small, Scale Intentionally: Begin with affordable AI tools and gradually incorporate human assistance as your budget and needs evolve, building trust and compounding leverage over time.
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December 8, 2025

Building The Chip That Could Unlock AGI | Naveen Rao

a16z

AI
Key Takeaways:
  1. **Embrace Analog:** Explore and invest in analog computing solutions to overcome the energy limitations of current digital AI systems.
  2. **Prioritize Causality:** Shift focus towards AI models that incorporate time and causality, potentially unlocking more advanced and human-like intelligence.
  3. **Support Hardware Innovation:** Invest in and foster startups like Unconventional AI that are tackling fundamental challenges in AI hardware.
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December 8, 2025

Why AI Will Have To Run On Blockchains

The DCo Podcast

AI
Key Takeaways:
  1. Blockchain is essential for AI to ensure censorship resistance and uninterrupted accessibility.
  2. Trustworthy AI agents require on-chain governance to manage assets securely and transparently.
  3. AI agents can drastically accelerate blockchain adoption and optimize corporate processes.
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Crypto Podcasts

March 18, 2025

Joe McCann on Why Bitcoin Is the King and Memecoins Are Over—For Now

Unchained

Crypto

Key Takeaways:

  • 1. While the current landscape for meme coins and certain trading strategies seems saturated, innovation and new implementations will drive the next wave of opportunities.
  • 2. Macroeconomic forces, particularly institutional deleveraging, are significant drivers of recent market fluctuations, but long-term fundamentals remain strong for Bitcoin and select altcoins like Solana.
  • 3. The convergence of AI and crypto holds immense potential, with orchestration playing a key role in unlocking value and efficiency across various applications.
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March 18, 2025

Why Solana’s Inflation Proposal Didn’t Pass | Weekly Roundup

Lightspeed

Crypto

Key Takeaways:

  • 1. Solana's governance processes are still evolving, requiring careful consideration of community sentiment and communication strategies.
  • 2. The Solana Foundation’s delegation program is a critical area for evaluation and potential restructuring to address decentralization concerns.
  • 3. Ethereum faces crucial decisions regarding its L1 and L2 strategy, with scaling the L1 being essential for long-term value capture.
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March 18, 2025

Alex Gluchowski and Sreeram Kannan on Their Collaborative Scaling Vision

The Rollup

Crypto

Key Takeaways:

  • 1. ZK technology is essential for scaling verifiability and enabling privacy, which are critical for broader blockchain adoption.
  • 2. The zkSync and EigenLayer partnership creates a synergistic combination of cryptographic and cryptoeconomic security, strengthening the ecosystem and ensuring greater resilience.
  • 3. The implementation of EigenLayer's novel slashing mechanism enhances the security and trustworthiness of decentralized services, paving the way for a more robust and reliable decentralized future.
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March 17, 2025

How Arbitrum is Pushing the Limits | Steven Goldfeder

0xResearch

Crypto

Key Takeaways:

  • 1. Timeboost could reshape the MEV landscape on Arbitrum, benefiting both regular users and the chain itself.
  • 2. Interoperability hinges on improving user experience, not just on developing complex technical solutions.
  • 3. Arbitrum’s long-term vision and commitment to ecosystem neutrality are key differentiators in the competitive L2 market.
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March 17, 2025

The State Of Crypto Lending | Membrane Labs

Empire

Crypto

Key Takeaways:

  • 1. While the crypto lending landscape has evolved since 2022, with improved risk management and new players, systemic risks remain.
  • 2. The convergence of centralized and decentralized finance creates new opportunities but also introduces novel challenges and potential vulnerabilities.
  • 3. Custodians stepping into lending services, coupled with increased regulatory clarity, could unlock significant growth in the crypto lending market.
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March 17, 2025

How Mode Network is the Ultimate Breeding Ground for the Cross Section of Crypto and AI | Explained

blocmates.

Crypto

Key Takeaways:

  • 1. Mode Network's focus on user experience, AI integration, and robust data infrastructure positions it as a promising platform for DeFi mass adoption.
  • 2. The innovative veTokenomics model aligns incentives and empowers community governance, fostering a thriving ecosystem.
  • 3. The convergence of DeFi and AI has the potential to unlock new financial opportunities and reshape the way users interact with blockchain technology.
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