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AI Podcasts

December 17, 2025

Rethinking Pre-Training for Agentic AI [Aakanksha Chowdhery] - 759

The TWIML AI Podcast with Sam Charrington

AI
Key Takeaways:
  1. Pre-Training is the New Frontier: The next leap in AI capabilities, particularly for agentic systems, will come from fundamental advancements in pre-training, not just post-training tweaks.
  2. Builders & Investors: Focus on teams rethinking loss objectives, curating high-quality reasoning data, and developing dynamic benchmarks for agentic capabilities. Be wary of "agentic" claims that lack foundational pre-training innovation.
  3. The "So What?": Over the next 6-12 months, expect a push for new benchmarks and data strategies that explicitly train models for multi-step planning, long-form reasoning, and error recovery, moving beyond simple next-token prediction.
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December 16, 2025

What We Learned Deploying AI within Bloomberg’s Engineering Organization – Lei Zhang, Bloomberg

AI Engineer

AI
Key Takeaways:
  1. Strategic Implication: AI fundamentally changes the economics of software development. Organizations must re-evaluate what constitutes "high-quality" engineering and adapt their processes.
  2. Builder/Investor Note: Prioritize platforms that provide guardrails and guidance for AI tool usage, focusing on deterministic verification and robust testing. Uncontrolled AI deployment risks technical debt.
  3. The "So What?": The next 6-12 months will see a bifurcation: companies that strategically integrate AI into their engineering culture and platforms will gain significant efficiency, while those that don't will struggle with quality and adoption.
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December 16, 2025

Your Support Team Should Ship Code – Lisa Orr, Zapier

AI Engineer

AI
Key Takeaways:
  1. Workflow Automation is the New Frontier: The real value of AI in developer tools comes from orchestrating entire workflows, not just individual point solutions.
  2. Embed for Adoption: Tools must integrate seamlessly into existing workflows and IDEs (like Cursor) to achieve high usage.
  3. Support as a Code-Shipping Powerhouse: Empowering non-traditional roles with AI-driven code generation leverages their unique, real-time context, creating significant operational leverage.
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December 17, 2025

Code World Model: Building World Models for Computation – Jacob Kahn, FAIR Meta

AI Engineer

AI
Key Takeaways:
  1. Semantic Shift: The future of AI in code moves from text generation to deep semantic understanding and execution simulation.
  2. Builder Opportunity: Develop next-generation debugging tools and code agents that leverage internal simulation for faster, more efficient development cycles.
  3. Investor Focus: Prioritize models and platforms that demonstrate explicit execution modeling, as this capability will redefine software development and create new market leaders.
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December 17, 2025

AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs

AI Engineer

AI
Key Takeaways:
  1. Infrastructure Shift: AI-driven kernel optimization addresses a critical bottleneck in scaling AI compute, enabling more efficient use of diverse hardware.
  2. Builder/Investor Note: Focus on solutions with robust, hardware-verified performance metrics and a clear human-in-the-loop strategy. AI is a powerful tool for automating optimization, not a magic bullet for novel algorithmic breakthroughs.
  3. The "So What?": This technology frees expert engineers from tedious optimization, allowing them to focus on higher-level research and truly innovative algorithmic design, accelerating the pace of AI development in the next 6-12 months.
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December 16, 2025

Finding The 1% of Stocks That Matter | Henry Ellenbogen Interview

Invest Like The Best

AI
Key Takeaways:
  1. Strategic Implication: The era of "free money" inflated the number of perceived compounders; a return to positive real rates demands a sharper focus on businesses demonstrating genuine financial discipline and competitive advantage.
  2. Builder/Investor Note: Seek out "Act 2" entrepreneurs and companies that can leverage AI to transform existing physical or IP-based advantages, not just create new AI products. Be prepared to buy more when market sentiment turns negative on strong businesses.
  3. The "So What?": The next 6-12 months will differentiate companies that merely adopt AI from those that strategically integrate it to build durable, uncatchable cost and distribution advantages.
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December 17, 2025

“How We Can Eliminate Crime” | Ben Horowitz and Garrett Langley

a16z

AI
Key Takeaways:
  1. The Future of Policing is Intelligent: Integrating AI, drones, and smart cameras creates a precise, accountable, and safer policing model for both officers and communities.
  2. Invest in the "How": Builders and investors should focus on technologies that enhance certainty of capture, streamline judicial processes, and support public-private partnerships to modernize urban safety infrastructure.
  3. Safety Fuels Mobility: Eliminating crime is not just about law enforcement; it's about restoring the fundamental safety required for economic mobility and a functional society.
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December 18, 2025

Two Futures | Runtime 2025

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next decade's value will accrue to those building foundational AI infrastructure and the "invisible layers" that connect intelligent systems.
  2. Builder/Investor Note: Focus capital and talent on core AI models, specialized domain intelligence, and the underlying computational fabric. Superficial applications risk rapid commoditization.
  3. The So What?: This is the defining period for the architecture of global intelligence. Participation now determines future influence and relevance.
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December 16, 2025

⚡️Jailbreaking AGI: Pliny the Liberator & John V on Red Teaming, BT6, and the Future of AI Security

Latent Space

AI
Key Takeaways:
  1. Strategic Shift: AI security must move beyond superficial guardrails to a full-stack, offensive red-teaming approach that accounts for the expanding attack surface of AI agents and their tool access.
  2. Builder/Investor Note: Builders should prioritize integrating offensive security early in development. Investors should be wary of "security theater" and favor solutions that embrace open-source collaboration and address the entire AI application stack.
  3. The "So What?": The accelerating pace of AI development means static security solutions will quickly become obsolete. Proactive, community-driven, and full-stack security research is essential for navigating the next 6-12 months of AI evolution.
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Crypto Podcasts

January 24, 2026

Gold Sets the Bar, But Bitcoin Can Catch Up. Here’s How: Bits + Bips

Unchained

Crypto
Key Takeaways:
  1. The institutionalization of Bitcoin has temporarily sacrificed its digital gold status for liquidity, creating a massive opportunity for those who can stomach the volatility before the next decoupling.
  2. Monitor Japanese government bond yields as a leading indicator for global risk tolerance.
  3. Bitcoin is currently a liquidity sponge, not a bunker. Expect it to follow the Trump Put and tech earnings until its volatility profile mirrors a currency rather than a speculative stock.
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January 23, 2026

The Intersection of AI and Crypto: What Worked, What Didn’t, and What’s Next | Roundup

Bell Curve

Crypto
Key Takeaways:
  1. The market is moving from the "Compute Layer" to the "Agentic Layer." Owning the GPU is less valuable than owning the agent that controls the wallet.
  2. Build agent-first interfaces. Stop designing for human clicks and start structuring your data so an LLM can execute transactions on your behalf.
  3. The next 12 months belong to on-chain agents that handle treasury ops and commerce. The "decentralized GPU" narrative is dead. The "AI Agent with a bank account" narrative is just beginning.
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January 23, 2026

The “Quantum Threat” Behind Bitcoin’s Sudden Sell-Off

Bankless

Crypto
Key Takeaways:
  1. The transition from global cooperation to regional protectionism is driving a capital outflow loop that favors hard assets over sovereign debt.
  2. Monitor the development of quantum-resistant signatures on alternative L1s to hedge against Bitcoin’s potential cryptographic obsolescence.
  3. The next year will be defined by the race to tokenize real-world assets and the struggle to maintain protocol relevance as TradFi giants enter the arena.
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January 22, 2026

DePIN’s Biggest New Deal: Valeo x NATIX | Alireza Ghods

Proof of Coverage Media

Crypto
Key Takeaways:
  1. The transition from digital-only AI to Physical AI requires a massive bridge of high-fidelity video data.
  2. Monitor DePIN projects that move from "map-to-earn" to "train-to-earn" for foundational models.
  3. NATIX is no longer just a mapping company; it is the data refinery for the next generation of autonomous machines.
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January 21, 2026

Markets Are Entering A Wartime Economy | Cem Karsan

Forward Guidance

Crypto
Key Takeaways:
  1. The transition from a supply-side model to a populist-driven wartime economy makes inflation a permanent feature rather than a bug.
  2. Rotate out of traditional portfolios into non-correlated volatility strategies and hard assets.
  3. The next decade belongs to those who recognize that the rules-based order has been replaced by a raw competition for strategic resources.
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January 21, 2026

How Nansen’s New Trading Agent Makes It Easier to Follow the Smart Money Onchain

Unchained

Crypto
Key Takeaways:
  1. The commoditization of technical infrastructure means alpha moves from who has the data to who has the best prompts.
  2. Test agentic workflows with small capital amounts to identify where natural language outperforms manual execution.
  3. The next 12 months will see a transition from manual click-and-sign trading to intent-based portfolio management.
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